Silk Fibroin Material with Enhanced Performances Using Poly(D, L-Lactide-Co-Glycolide) DOI

Jingwen Lan,

Rukuan Liu, Sisi Liu

et al.

Polymer-Plastics Technology and Materials, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 8

Published: Dec. 12, 2024

Eco-friendly silk fibroin/poly(D,L-lactide-co-glycolide) (SF/PLGA) materials were successfully fabricated using a facile strategy. The characterized by scanning electron micrograph (SEM), X-ray diffraction (XRD) and infrared spectra (IR). Systematic investigations completed to examine the degradation rates in natural soil, cytocompatibility thermostability of materials. It is interesting find that after SF was hybridized PLGA, rate increased. Meanwhile, show good cytocompatibility. SEM, IR XRD results reveal there hardly any interaction between PLGA SF/PLGA material, physically mixed with PLGA. This study opens up new horizon design preparation SF-based for promising applications medical biodegradable material fields.

Language: Английский

How swelling affects microscale creasing and stick-slip friction of soft elastomers DOI Creative Commons
Sazzadul A. Rahat, Rong Long, Jonathan T. Pham

et al.

Tribology International, Journal Year: 2025, Volume and Issue: unknown, P. 110794 - 110794

Published: May 1, 2025

Language: Английский

Citations

0
Engineering a durable BDDE cross-linked collagen filler for skin rejuvenation DOI
Qi Wang,

Huiyu Yan,

Jingting Zhang

et al.

Biomedical Materials, Journal Year: 2024, Volume and Issue: 19(5), P. 055021 - 055021

Published: July 29, 2024

Abstract Skin aging, characterized by reduced regeneration, chronic inflammation, and heightened skin cancer risk, poses a significant challenge. Collagen fillers have emerged as potential solution for rejuvenation stimulating collagen regeneration. However, their clinical efficacy is limited inherent instability vulnerability to in vivo degradation collagenase. Chemical cross-linking presents promising approach enhance stability, but it carries risks such cytotoxicity, calcification, discoloration. Here, we introduce highly durable 1,4-butanediol diglycidyl ether (BDDE) cross-linked filler rejuvenation. BDDE effectively cross-links collagen, resulting with exceptional mechanical strength injectability. These demonstrate favorable stability durability, promoting proliferation, adhesion, spreading of human foreskin fibroblast-1 cells vitro. In studies confirm enhanced regeneration without inducing calcification. offer prospects medical cosmetology tissue

Language: Английский

Citations

3
Silk Fibroin Material with Enhanced Performances Using Poly(D, L-Lactide-Co-Glycolide) DOI

Jingwen Lan,

Rukuan Liu, Sisi Liu

et al.

Polymer-Plastics Technology and Materials, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 8

Published: Dec. 12, 2024

Eco-friendly silk fibroin/poly(D,L-lactide-co-glycolide) (SF/PLGA) materials were successfully fabricated using a facile strategy. The characterized by scanning electron micrograph (SEM), X-ray diffraction (XRD) and infrared spectra (IR). Systematic investigations completed to examine the degradation rates in natural soil, cytocompatibility thermostability of materials. It is interesting find that after SF was hybridized PLGA, rate increased. Meanwhile, show good cytocompatibility. SEM, IR XRD results reveal there hardly any interaction between PLGA SF/PLGA material, physically mixed with PLGA. This study opens up new horizon design preparation SF-based for promising applications medical biodegradable material fields.

Language: Английский

Citations

0