International Journal of Polymeric Materials,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 33
Published: Dec. 16, 2024
This
review
delves
into
the
efficacy
of
electrospun
nanofibers
as
structures
capable
neutralizing
Reactive
Oxygen
Species
(ROS),
thereby
aiding
in
acceleration
wound
repair.
ROS
occupy
a
dual
position
cellular
dynamics,
being
indispensable
for
intracellular
communication,
yet
they
potentially
exacerbate
oxidative
stress
which
can
stall
healing
trajectory.
The
method
electrospinning
synthesizes
distinguished
by
their
expansive
surface
area
relative
to
volume
and
notable
porosity,
rendering
them
optimally
suited
medical
endeavors,
particularly
frameworks
that
bolster
recuperation.
analysis
elucidates
diverse
roles
these
play,
from
enhancing
clot
formation
combating
microbial
invasion
mitigating
inflammation,
fostering
proliferation,
facilitating
angiogenesis—each
pivotal
component
effective
mending
wounds.
Journal of Functional Biomaterials,
Journal Year:
2025,
Volume and Issue:
16(1), P. 20 - 20
Published: Jan. 10, 2025
In
recent
years,
several
studies
have
focused
on
the
development
of
sustainable,
biocompatible,
and
biodegradable
films
with
potential
applications
in
wound
healing
dressing
systems.
Natural
macromolecules,
particularly
proteins,
emerged
as
attractive
alternatives
to
synthetic
polymers
due
their
biocompatibility,
biodegradability,
low
immunogenicity,
adaptability.
Among
these
keratin,
extracted
from
waste
wool,
fibroin,
derived
Bombyx
mori
cocoons,
exhibit
exceptional
properties
such
mechanical
strength,
cell
adhesion
capabilities,
suitability
for
various
fabrication
methods.
These
proteins
can
also
be
functionalized
antimicrobial,
antioxidant,
anti-inflammatory
compounds,
making
them
highly
versatile
biomedical
applications.
This
review
highlights
promising
keratin-
fibroin-based
innovative
platforms
healing,
emphasizing
advantages
prospects
they
offer
creating
next-generation
devices.
Polymers,
Journal Year:
2025,
Volume and Issue:
17(3), P. 425 - 425
Published: Feb. 6, 2025
Silk
fibroin
(SF)-based
hydrogels
were
prepared
by
the
simple
evaporation
method.
The
outcomes
of
SF-based
assessed
for
consideration
in
terms
practical
and
convenient
use.
Guar
gum
(GG)
sodium
benzoate
(SB)
are
blending
reagents
to
SF
solution
poured
into
petri
dish
make
hydrogels.
After
leaving
mixture
three
days
solidify,
all
peeled
off
characterized.
SF-blend
guar
(SF-GG)
SF-GG-blend
(SF-GG-SB)
could
be
constructed,
but
different
textures
levels
transparency.
SB
affected
solid
texture
resulted
a
higher
water
contact
angle
(WCA)
value
hydrogel
than
SF-GG.
results
from
Fourier
transform
infrared
spectroscopy
(FTIR)
indicated
main
functional
groups
substances
that
contained
Moreover,
some
interactions
between
also
detected.
A
thermogravimetric
analyzer
(TGA)
was
used
determine
decomposition
as
function
temperature.
DTG
thermograms,
which
exhibit
maximum
temperature,
revealed
interaction
forces
SF,
well
their
structure,
reason
thermal
stability
SF-GG-SB
have
tensile
strength
SF-GG
In
conclusion,
appearance,
texture,
hydrophilicity,
stability,
types
concentrations
substances.
This
suggests
properties
designed
adjusted
attain
desirable
fitting
target
applications.
Pharmaceuticals,
Journal Year:
2024,
Volume and Issue:
17(10), P. 1305 - 1305
Published: Sept. 30, 2024
Non-healing
diabetic
wounds
represent
a
significant
clinical
challenge
globally,
necessitating
innovative
approaches
in
drug
delivery
to
enhance
wound
healing.
Understanding
the
pathogenesis
of
these
is
crucial
for
developing
effective
treatments.
Bioactive
dressings
and
polymeric
nanofibers
have
emerged
as
promising
modalities,
with
silk
biomaterials
gaining
attention
their
unique
properties
Advanced Materials Technologies,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 17, 2024
Abstract
Extrusion‐based
3D
printing
technology
is
currently
demonstrating
considerable
potential
in
the
field
of
tissue
engineering
scaffolds,
enabling
construction
vitro
models
with
complex
structures
and
functions
using
a
wide
range
biomaterials
cells
at
low
cost.
In
recent
years,
researchers
have
spent
effort
developing
novel
bio‐inks
employing
greater
variety
cell
sources
to
enhance
biological
compatibility
functionality.
However,
majority
current
bio‐ink
materials
are
unprintable
due
their
viscosity
long
curing
time,
as
well
insufficient
shape
fidelity
before
secondary
cross‐linking
process.
The
study
aims
bridge
this
gap
by
optimizing
material
ratios
predicting
process
work.
This
article
presents
new
strategies
for
design,
fabrication,
analysis
composite
material.
optimal
ink
verified
design
experiments
(DOE)
experimental
evaluation
metrics
printability
(Pr)
values.
A
machine
learning
model
used
predict
area
determine
parameters.
influence
mechanism
different
concentrations
poly
(ethylene
glycol)
diacrylate
(PEGDA)
on
printed
fibers
investigated.
Finally,
results
an
example
demonstrate
multilayer
stents.
Thus,
approach
allows
rapid
cost‐effective
exploration
ratios,
while
also
providing
higher
more
accurate
fabrication
multidimensional
variables.
Polymers,
Journal Year:
2024,
Volume and Issue:
16(21), P. 3020 - 3020
Published: Oct. 28, 2024
Microparticles
derived
from
biomaterials
are
becoming
increasingly
popular
for
application
in
drug
delivery
systems.
In
this
study,
the
water-in-oil
(W/O)
emulsification–diffusion
method
was
used
to
create
cellulose
(C),
silk
fibroin
(SF),
and
C/SF
composite
microparticles.
We
then
observed
morphology
of
all
obtained
microparticles
using
scanning
electron
microscopy
(SEM),
evaluated
their
functional
groups
attenuated
total
reflection–Fourier
transform
infrared
spectroscopy
(ATR-FTIR),
conducted
thermogravimetric
analysis
a
analyzer
(TGA).
SEM
micrographs
indicated
that
native
SF
have
highest
spherical
shape
with
smooth
surfaces.
With
blue
dextran,
C
microparticle
smaller
than
microparticle,
while
drug-loaded
were
larger
microparticle.
The
morphological
surfaces
varied
surface
depending
on
ratio
used.
increased
as
content
increased.
Furthermore,
size
when
gradually
significant
structures
identified
based
ATR-FTIR
data,
suggestion
made
regarding
interaction
between
each
polymer.
When
compared
both
polymers,
exhibit
improved
thermal
stability.
XRD
patterns
prepared
particles
crystalline
directly
affected
by
released
profile.
at
1:3
had
lowest
release
content,
whereas
hydrophilicity
content.
As
result,
one
crucial
factor
affecting
medication
is
its
structure
According
results,
C,
SF,
show
promise
systems
drugs
controlled
release.
