Nanostructures and nanoparticles as medical diagnostic imaging contrast agents: A review

Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 40, P. 102233 - 102233

Published: Aug. 5, 2024

Language: Английский

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Acoustic tweezers for targeted drug delivery

Advanced Drug Delivery Reviews, Journal Year: 2025, Volume and Issue: unknown, P. 115551 - 115551

Published: Feb. 1, 2025

Language: Английский

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Low-Intensity Focused Ultrasound-Responsive Phase-Transitional Liposomes Loaded with STING Agonist Enhances Immune Activation for Breast Cancer Immunotherapy

Cancers, Journal Year: 2024, Volume and Issue: 16(21), P. 3657 - 3657

Published: Oct. 30, 2024

Pharmacologically targeting the STING pathway offers a novel approach to cancer immunotherapy. However, small-molecule agonists face challenges such as poor tumor accumulation, rapid clearance, and short-lived effects within microenvironment, thus limiting their therapeutic potential. To address of specificity inadequate in breast treatment, herein, we report design development targeted liposomal delivery system modified with tumor-targeting peptide iRGD (iRGD-STING-PFP@liposomes). With LIFU irradiation, exploits acoustic cavitation, where gas nuclei form collapse hydrophobic region liposome lipid bilayer (transient pore formation), which leads significantly enhanced drug release.

Language: Английский

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The Neoteric Paradigm of Biomolecule-Functionalized Albumin-Based Targeted Cancer Therapeutics

AAPS PharmSciTech, Journal Year: 2024, Volume and Issue: 25(8)

Published: Nov. 5, 2024

Language: Английский

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