Harnessing bioactive nanocurcumin and curcumin nanocomposites to combat microbial pathogens: a comprehensive review

Critical Reviews in Biotechnology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 23

Published: Feb. 20, 2025

The alarming rise in bacterial infections including those caused by multidrug-resistant pathogens has garnered the attention of scientific community, compelling them to explore as novel and effective alternatives combat these infections. Moreover, emerging viruses such Influenza A virus subtype H1N1 (A/H1N1), Middle East Respiratory Syndrome Coronavirus (MERS-CoV), Ebolavirus, recent coronavirus (SARS-CoV-2), etc. also a significant impact all over world. Therefore, management without any side effects is one most important challenges for community. Hence, development antimicrobial agents need hour. In this context, Curcuma longa, commonly known turmeric, been used traditional medicine centuries manage treat Its bioactive constituent, curcumin due its multifunctional bioactivities. Apart from properties, it possesses potent antioxidant anti-inflammatory activities. However, available reports suggest that low solubility, stability, biocompatibility limit use. on other hand, reported limitations associated with use can be resolved transforming into nano-form, specifically nanoparticles. Recent advancements have brought nanoparticles spotlight, showcasing superior properties broad spectrum applications. review, we mainly focused potential nanocurcumin, mechanisms underpinning their actions. aspects toxicity safety guidelines nano-based products discussed.

Language: Английский

Paradigm shift in orthopedic implants from metals to polymers

Iranian Polymer Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 19, 2024

Language: Английский