A thermoresponsive system of niclosamide for colon specific delivery in ulcerative colitis: Bioavailability and safety investigation
Journal of Drug Delivery Science and Technology,
Journal Year:
2025,
Volume and Issue:
unknown, P. 106641 - 106641
Published: Jan. 1, 2025
Language: Английский
Formulations with Boric Acid or Aryl-Organoboron Compounds for Treating Diabetic Foot Ulcers
Scientia Pharmaceutica,
Journal Year:
2025,
Volume and Issue:
93(1), P. 14 - 14
Published: March 19, 2025
Boron-containing
compounds
(BCCs)
have
been
proposed
for
the
treatment
of
diabetes
and
its
complications.
Recent
studies
reported
an
improvement
in
design
development
pharmaceutical
formulations
(often
gels)
containing
boric
acid
applied
to
foot
ulcers
humans
diagnosed
with
diabetes.
The
mechanisms
action
include
antimicrobial
effects,
modulation
inflammation
metabolism,
induction
cell
differentiation.
On
other
hand,
recent
suggested
that
boronic
acids
are
potent
antibacterial
antifungal
compounds,
effective
modulators
inflammation,
inducers
vascular
regeneration
as
well
healing,
they
confer
attractive
properties
such
adhesion,
interaction,
formation
complexes
formulations.
Moreover,
only
a
handful
conducted
animals
role
some
BCCs
enhancers
wound
including
their
actions
on
induced
and/or
infected
wounds
disrupted
metabolism.
Also,
it
should
be
mentioned
no
strong
interactions
between
present
described.
developed
combination
could
act
additive
complementary
therapy
diabetic
humans.
Further
required
support
hypothesis
this
acts
through
diverse
improve
healing
while
avoiding
or
limiting
local
disseminated
infection.
Furthermore,
safety
used
established,
these
current
protocols
treating
patients
ulcers.
Language: Английский
Improved biopharmaceutical performance of chlorpromazine-nanostructured lipid carriers: In vitro release, pharmacokinetics and toxicity testing
Khushi Muhammad,
No information about this author
Uswa Shafique,
No information about this author
Abad Khan
No information about this author
et al.
Journal of Drug Delivery Science and Technology,
Journal Year:
2025,
Volume and Issue:
unknown, P. 106885 - 106885
Published: April 1, 2025
Language: Английский
Comparative analysis of novel modified drug delivery systems for improving the oral bioavailability of water-insoluble tadalafil using copovidone, TPGS and hydroxypropyl-β-cyclodextrin
Biomedicine & Pharmacotherapy,
Journal Year:
2025,
Volume and Issue:
186, P. 118039 - 118039
Published: April 8, 2025
Language: Английский