Advances in Organic Fluorescent and Colorimetric Probes for The Detection of Cu ²⁺ and Their Applications in Cancer Cell Imaging (2020–2024)

Critical Reviews in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 27

Published: Jan. 21, 2025

Organic fluorescence and colorimetric probes have emerged as vital tools for detecting metal ions, due to their high sensitivity, selectivity, rapid response times. Copper, an essential trace element, plays a critical role in biological systems, yet its imbalance can lead severe disorders such neurodegenerative diseases, cancer, Wilson's disease. Over the past few years, advancements probe design unlocked innovative avenues not only Cu2+ environmental samples but also visualizing distribution through imaging. These offering robust performance under diverse conditions. Fluorescence imaging using these pivotal cancer diagnosis, prognosis, treatment monitoring by real-time visualization of tumor morphology biomolecular interactions at cellular tissue levels. This review aims explore diversity organic developed detection Cu2+, with particular focus on applications from 2020 2024. The discussion highlights use various cells SiHa, HCT 116, GES-1, RAW 264.7, HepG2, HeLa, MCF-7 DrG cell lines, tissues, small living organisms. By targeting cancer-specific pathways copper-related physiological changes, significantly advanced fields diagnostics therapeutics. comprehensive analysis emphasizes potential powerful tool elucidating roles health disease, paving way future advances biomedical research.

Language: Английский

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Recent Developments in Colorimetric and Fluorimetric Chemosensors for the Detection of Mn ²⁺ Ions: A Review (2010–2024)

Critical Reviews in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 21

Published: Feb. 19, 2025

Manganese is an essential metal ion involved in various biological and environmental processes, but its excess can lead to toxicity, particularly affecting the nervous system. Therefore, developing selective sensitive detection methods for Mn2+ ions of paramount importance. Colorimetric fluorimetric chemosensors have emerged as promising tools due their simplicity, cost-effectiveness, real-time monitoring capabilities. This review discusses recent advances colorimetric that exhibit distinct color or fluorescence changes upon interaction with ions. The explores different organic nanomaterials, focusing on mechanisms sensing, sensitivity, selectivity, practical applications monitoring, healthcare, food safety. article also provides insights into future research directions aimed at overcoming these challenges, improving chemosensor performance, expanding applicability diverse real-world scenarios.

Language: Английский

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Recent Progress in ESIPT-Based Fluorescent Chemosensors for Detection of Zn2+, Mg2+ and Cu2+

Dyes and Pigments, Journal Year: 2024, Volume and Issue: unknown, P. 112509 - 112509

Published: Oct. 1, 2024

Language: Английский

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Nonconventional Luminescent Polymers with Efficient Emission in Dilute Solutions for Lysosome Targeting and Al³⁺ Detection

ACS Applied Polymer Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 29, 2025

Language: Английский

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A turn-on fluorescent chemical sensor based on imidazole-Schiff base structure for highly selective and accurate detection of Al3+ ions in living cells

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: March 3, 2025

An imidazole-Schiff base fluorescent probe EBI was designed and synthesized for the sensitive selective detection of Al³⁺. The exhibits good anti-interference performance against Al³⁺ in presence multiple metal ions. reaction reached platform about 30 min after adding Al³⁺, fluorescence limit 1.62 nM. coordination ratio to is 1:1, between carbonyl group, hydroxyl –HN–N=C– limits molecular distortion quenching effect photoelectron transfer, thus inducing enhancement green fluorescence. can be recovered used alternately by EDTA In addition, EBI–Al³⁺ PO₄³⁻ also evident selected anion range. applied successful monitoring living cells.

Language: Английский

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Recent Advances in Dual-Channel Colorimetric and Fluorometric Probes for Selective Sn2+ Detection: Bioimaging and Environmental Perspectives

Dyes and Pigments, Journal Year: 2025, Volume and Issue: unknown, P. 112800 - 112800

Published: April 1, 2025

Language: Английский

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Pyridine-based fluorescent and colorimetric probes: Advances in metal ion detection and cancer cell imaging (2020–2024)

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113716 - 113716

Published: April 1, 2025

Language: Английский

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