Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 163043 - 163043
Published: April 1, 2025
Language: Английский
Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 163043 - 163043
Published: April 1, 2025
Language: Английский
Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 490, P. 137753 - 137753
Published: Feb. 25, 2025
Language: Английский
Citations
1Separation and Purification Technology, Journal Year: 2025, Volume and Issue: unknown, P. 132917 - 132917
Published: April 1, 2025
Language: Английский
Citations
0ACS Applied Bio Materials, Journal Year: 2025, Volume and Issue: unknown
Published: May 2, 2025
Covalent organic frameworks (COFs) show great potential as drug delivery systems (DDSs) due to their customizable structures, stability, and capacity for pore surface functionalization. However, natural hydrophobicity limits dispersion in water, posing challenges biological applications. We address this issue by initially reducing a COF (Az-COF) an amine-linked form (Az-AL-COF) subsequently sulfonating it obtain Az-AL-SO3H-COF, water-dispersible derivative. Water contact angle (WCA) analysis confirmed increased hydrophilicity across the series of 84.5, 61.2, 54.7° Az-COF, Az-AL-COF, respectively. Using doxorubicin (Dox) model drug, modified COFs exhibited pH-sensitive release, with greater release at acidic pH (5.6) compared neutral (7.4). Cytotoxicity assays revealed that Az-AL-SO3H-COF was biocompatible normal cells (MCF-10) while effectively suppressing growth cancer (MDA-MB-231). The Dox-loaded sulfonated (Dox@Az-AL-SO3H-COF) showed selective cytotoxicity against cells, highlighting its pH-responsive, DDS treatment.
Language: Английский
Citations
0Journal of Physics Conference Series, Journal Year: 2025, Volume and Issue: 3008(1), P. 012031 - 012031
Published: May 1, 2025
Abstract The [4+4]-type Covalent Organic Frameworks material TAPP-TFPB-COF was synthesized by using 1, 2, 4, 5-Tetrakis-(4-formylphenyl) benzene (TFPB) and 5,10,15,20- Tetra(p-amino-phenyl) porphyrin (TAPP) as monomers via Schiff base reaction. macroscopic structure is a two-dimensional layered assembled stacked in layers to form three-dimensional with micrometer size. Its pore size 1.20 nm regular its specific surface area 1107.3 m 2 g − 1 . It has good adsorption capacity for the model dye RhB at room temperature. In addition, could continue degrade photocatalysis under visible light irradiation after saturation of adsorption. had stability reusability. able achieve continuous removal dark conditions.
Language: Английский
Citations
0Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 163043 - 163043
Published: April 1, 2025
Language: Английский
Citations
0