Microcystin‐Lr‐Induced Changes in Growth Performance, Intestinal Microbiota, and Lipid Metabolism of Black Soldier Fly Larvae (Hermetia illucens) DOI
Peng Gu,

Yi Ding,

Wanqing Zhang

et al.

Archives of Insect Biochemistry and Physiology, Journal Year: 2025, Volume and Issue: 118(2)

Published: Feb. 1, 2025

ABSTRACT Biological treatment by black soldier fly larvae (BSFL) has proven to be an effective method for the resource utilization of cyanobacteria, but effects microcystin‐LR (MC‐LR) in cyanobacteria on BSFL growth have not been adequately explored. To evaluate inhibitory effect and toxic mechanism MC‐LR BSFL, performance intestinal microbiota were examined after exposure 0, 10, 100, 1000 μg/kg MC‐LR. The larval weight survival rate each significantly inhibited 21.53% 21.49% compared with control group, respectively, at a concentration 16 days. Lipid accumulation, inflammation, oxidative stress observed three groups, dose‐dependent inflammation ocurring intestine. Compared superoxide dismutase catalase activity levels increased 74.91% 49.58%, which confirmed occurrence induced Furthermore, altered diversity relative abundance pathogenic bacteria (e.g., Paenibacillus , Clostridium_sensu_stricto_1 Lachnoclostridium ), risk disease contributed metabolic disorders. On other hand, qRT‐PCR analysis further activation peroxisome proliferator‐activated receptor signaling pathway, resulting upregulation fatty acid synthesis‐related genes, ultimately leading lipid accumulation apoptosis. These findings provide valuable insights into ecological risks associated during process cyanobacterial utilization.

Language: Английский

Microcystin‐Lr‐Induced Changes in Growth Performance, Intestinal Microbiota, and Lipid Metabolism of Black Soldier Fly Larvae (Hermetia illucens) DOI
Peng Gu,

Yi Ding,

Wanqing Zhang

et al.

Archives of Insect Biochemistry and Physiology, Journal Year: 2025, Volume and Issue: 118(2)

Published: Feb. 1, 2025

ABSTRACT Biological treatment by black soldier fly larvae (BSFL) has proven to be an effective method for the resource utilization of cyanobacteria, but effects microcystin‐LR (MC‐LR) in cyanobacteria on BSFL growth have not been adequately explored. To evaluate inhibitory effect and toxic mechanism MC‐LR BSFL, performance intestinal microbiota were examined after exposure 0, 10, 100, 1000 μg/kg MC‐LR. The larval weight survival rate each significantly inhibited 21.53% 21.49% compared with control group, respectively, at a concentration 16 days. Lipid accumulation, inflammation, oxidative stress observed three groups, dose‐dependent inflammation ocurring intestine. Compared superoxide dismutase catalase activity levels increased 74.91% 49.58%, which confirmed occurrence induced Furthermore, altered diversity relative abundance pathogenic bacteria (e.g., Paenibacillus , Clostridium_sensu_stricto_1 Lachnoclostridium ), risk disease contributed metabolic disorders. On other hand, qRT‐PCR analysis further activation peroxisome proliferator‐activated receptor signaling pathway, resulting upregulation fatty acid synthesis‐related genes, ultimately leading lipid accumulation apoptosis. These findings provide valuable insights into ecological risks associated during process cyanobacterial utilization.

Language: Английский

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