Efficacy and safety of Jiao Wei Xiao Shi decoction in patients with functional dyspepsia: A study protocol for a randomized controlled trial DOI Creative Commons
Feng Zhang, Siyu Huang,

Zilale Yusup

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: July 24, 2024

Abstract Background Functional dyspepsia (FD) is the most prevalent gastrointestinal disorder worldwide. Current medicine often faces limitations in treatment of FD. Traditional Chinese (TCM), with a history thousands years, offers great contribution to people Jiao Wei Xiao Shi decoction (JWXSD) traditional medical prescription. However, efficacy JWXSD FD lacking. Therefore, this study will evaluate and safety for Methods A randomized controlled trial be conducted at Beijing University Medicine. 72 participants randomly allocated three groups (JWXSD groups, Mosapride group Placebogroup) ratio 1:1:1. The primary outcome Nepean Dyspepsia Symptom Index (NDSI). secondary outcomes include Life Quality (NDLQI), Body Mass (BMI) Pittsburgh Sleep Index(PSQI). Primary evaluated weeks 1, 3, 4, 8, 12 16. Adverse events assessed during study. Discussion The from compare JWXSD, mosapride placebo participants. This provide clinical evidence that can help improve Trial registration Chinese Clinical Trial Registry: ChiCTR2400082798. Registered on April 2024.

Language: Английский

Speculation, climate or pandemic: Who drives the Chinese herbal medicine bubbles? DOI
Meng Qin,

Ai-Hsuan Su,

Ruifeng Li

et al.

China Economic Review, Journal Year: 2024, Volume and Issue: 87, P. 102213 - 102213

Published: June 7, 2024

Language: Английский

Citations

22
Curcumin is comparable to metformin for the treatment of PCOS in rats: a preclinical study DOI Creative Commons
Salam Shannag, Khawla Nuseir, Linda Tahaineh

et al.

Pharmacia, Journal Year: 2024, Volume and Issue: 71, P. 1 - 10

Published: Feb. 27, 2024

Background : Ploy cystic ovary syndrome (PCOS) is a common gynecological disorder affecting between 4–20% of females worldwide. Curcumin, the active ingredient in turmeric ( Curcuma longa Zingiberaceae) yellow polyphenol with wide range pharmacological activities such as antioxidant, anti-inflammatory, anti-tumor, neuroprotective and cardioprotective properties. Methods Letrozole was used to induce PCOS female Wistar rats. metformin, or combination both given assess their therapeutic effects. Body weight, estrogen, progesterone, testosterone, glucose levels were measured after disease induction at conclusion treatment. Additionally ovarian histomorphology examined sacrificing animals removal ovaries. Results Weight significantly reduced curcumin, metformin curcumin groups. Testosterone decreased, progesterone increased, normal morphology restored three Conclusions: therapeutically effective for comparable metformin.

Language: Английский

Citations

3
Predicting TCM patterns in PCOS patients: An exploration of feature selection methods and multi-label machine learning models DOI Creative Commons
Jiekee Lim, Jieyun Li, Xiao Feng

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(15), P. e35283 - e35283

Published: July 26, 2024

Traditional Chinese Medicine (TCM) offers individualized treatment for Polycystic Ovary Syndrome (PCOS) through pattern differentiation, but the subjectivity of TCM diagnoses can lead to inconsistent outcomes. Integrating machine learning (ML) an objective basis support diagnoses. This study aims evaluate various feature selection techniques and multi-label ML algorithms develop effective predictive model classifying patterns in PCOS patients, thereby enhancing diagnostic standardization personalization.

Language: Английский

Citations

2
Effect of Rhei Radix Et Rhizome on treatment of polycystic ovary syndrome by regulating PI3K/AKT pathway and targeting EGFR/ALB in rats DOI

Wanqi Yang,

Jiwan Qiu,

Jinhua Zi

et al.

Journal of Ethnopharmacology, Journal Year: 2024, Volume and Issue: 338, P. 119020 - 119020

Published: Nov. 2, 2024

Language: Английский

Citations

1
Efficacy and safety of Jiao Wei Xiao Shi decoction in patients with functional dyspepsia: A study protocol for a randomized controlled trial DOI Creative Commons
Feng Zhang, Siyu Huang,

Zilale Yusup

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: July 24, 2024

Abstract Background Functional dyspepsia (FD) is the most prevalent gastrointestinal disorder worldwide. Current medicine often faces limitations in treatment of FD. Traditional Chinese (TCM), with a history thousands years, offers great contribution to people Jiao Wei Xiao Shi decoction (JWXSD) traditional medical prescription. However, efficacy JWXSD FD lacking. Therefore, this study will evaluate and safety for Methods A randomized controlled trial be conducted at Beijing University Medicine. 72 participants randomly allocated three groups (JWXSD groups, Mosapride group Placebogroup) ratio 1:1:1. The primary outcome Nepean Dyspepsia Symptom Index (NDSI). secondary outcomes include Life Quality (NDLQI), Body Mass (BMI) Pittsburgh Sleep Index(PSQI). Primary evaluated weeks 1, 3, 4, 8, 12 16. Adverse events assessed during study. Discussion The from compare JWXSD, mosapride placebo participants. This provide clinical evidence that can help improve Trial registration Chinese Clinical Trial Registry: ChiCTR2400082798. Registered on April 2024.

Language: Английский

Citations

0