A global view of altered ligand-receptor interactions in bone marrow aging based on single-cell sequencing DOI Creative Commons
Wenbo Chen, Xin Chen, Lei Yao

et al.

Computational and Structural Biotechnology Journal, Journal Year: 2024, Volume and Issue: 23, P. 2754 - 2762

Published: June 20, 2024

Language: Английский

Key players inducing skin diseases and skin aging and potential preventive or therapeutic strategies using phytochemicals DOI Creative Commons
Hamid M. Abdolmaleky, Jin‐Rong Zhou

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown, P. 100073 - 100073

Published: Feb. 1, 2025

Language: Английский

Citations

0
Mixtures of EGCG, bamboo leaf flavonoids, and broccoli seed water extracts exhibit anti-glycation and skin-protective effects DOI
Chang Sun, Zibin Liu,

Mengmeng Feng

et al.

Phytomedicine, Journal Year: 2025, Volume and Issue: 140, P. 156592 - 156592

Published: March 12, 2025

Language: Английский

Citations

0
Determination via an Integration Strategy of the Potential Dermal ECM Reconstruction Mechanism by Which the WAW Formula Alleviates Skin Aging DOI Creative Commons
Yingying Lin, Yunhee Chang,

Yoojae Maeng

et al.

Journal of Cosmetic Dermatology, Journal Year: 2025, Volume and Issue: 24(4)

Published: March 31, 2025

ABSTRACT Background Traditional Chinese medicine (TCM) treats skin conditions and delays aging using specific formulas. TCM links health to internal organ functions: kidney qi deficiency accelerates aging, whereas spleen leads dry, loose from insufficient blood. The renowned spleen‐tonifying kidney‐nourishing formula “Wan An Wan” moisturizes the skin, but its antiageing mechanism remains unclear. Aims aim of this study was investigate development strategy comprehensive methodological framework for incorporating into cosmetics assess action application potential WAW in mitigating aging. Results In vitro experiments revealed that after optimizing extraction active ingredients tailored formula, it effectively inhibited NO production tyrosinase activity increased filaggrin, AQP, HAS2 mRNA expression. Moreover, ingredients, including morroniside, were also analyzed separately. Mechanistic studies upregulated expression TGF‐β1 gene associated with ECM downregulated MMP‐2/MMP‐9 genes degradation, regulating cell behaviors such as migration, adhesion, proliferation thereby maintaining healthy state skin. Conclusions study, an overall applying care solutions established, value modern dermatologic applications revealed, innovative raw materials effects developed, new ideas fields dermatology provided.

Language: Английский

Citations

0
A global view of altered ligand-receptor interactions in bone marrow aging based on single-cell sequencing DOI Creative Commons
Wenbo Chen, Xin Chen, Lei Yao

et al.

Computational and Structural Biotechnology Journal, Journal Year: 2024, Volume and Issue: 23, P. 2754 - 2762

Published: June 20, 2024

Language: Английский

Citations

1