Eriodictyol regulates white adipose tissue browning and hepatic lipid metabolism in high fat diet-induced obesity mice via activating AMPK/SIRT1 pathway DOI

Song-Xia Lin,

Xiaoyi Li,

Qi-Cong Chen

et al.

Journal of Ethnopharmacology, Journal Year: 2024, Volume and Issue: 337, P. 118761 - 118761

Published: Aug. 30, 2024

Language: Английский

Recent Developments in Citrus aurantium L.: An Overview of Bioactive Compounds, Extraction Techniques, and Technological Applications DOI Open Access
Joaquín Fernández-Cabal, Kevin Alejandro Avilés-Betanzos, Juan Valerio Cauich‐Rodríguez

et al.

Processes, Journal Year: 2025, Volume and Issue: 13(1), P. 120 - 120

Published: Jan. 5, 2025

This review provides an overview of recent developments in Citrus aurantium L. (sour or bitter orange), focusing on its bioactive compounds, innovative extraction techniques, and technological applications. C. is rich compounds such as flavonoids (naringin, hesperidin, kaempferol, quercetin), essential oils (β-pinene, limonene), vitamin C, which represents significant biological activities including antioxidant, antimicrobial, anti-inflammatory, anticancer effects. The discusses traditional methods, solvent hydrodistillation, alongside newer, eco-friendly approaches like ultrasound-assisted extraction, microwave-assisted supercritical fluid natural deep eutectic solvents. It also highlights cutting-edge molecular imprinting polymer-based enable the more efficient enrichment purification specific synephrine. Finally, examines diverse industrial applications these sectors foods, pharmaceuticals, cosmetics, while emphasizing growing need for sustainable technologies.

Language: Английский

Citations

3

Eriocitrin promotes browning of white adipose tissue and activates brown adipose tissue through regulating HSF1/PGC-1α pathways DOI

Qi-Cong Chen,

Chao Wu,

Wei‐Feng Cai

et al.

Journal of Functional Foods, Journal Year: 2025, Volume and Issue: 127, P. 106758 - 106758

Published: March 25, 2025

Language: Английский

Citations

0

Multiomics Analyses of Citrus aurantium L. Var. Amara and Ginger Reveals Lipid Metabolism, Bile Acid Biosynthesis, and Gut Microbiome Rebalance Supporting Their Anti‐Obesity Effects DOI Open Access
Ying Yang, Wentao Shao,

Huang Shu

et al.

Biomedical Chromatography, Journal Year: 2025, Volume and Issue: 39(5)

Published: March 27, 2025

ABSTRACT Both the flower of Citrus aurantium L. var. amara (CAVA) and rhizome Zingiber officinale Roscoe (ginger) are food medicinal homologous plants that have been used in China for aiding gastric digestion preventing obesity. However, combinatorial use two on obesity remains elusive. Our endeavor aimed to identify optimal synergistic ratio between CAVA ginger explore underlying mechanism their anti‐obesity effects. Aqueous extracts were prepared separately then combined into nine different ratios. The constituents unambiguously characterized by employing LC–MS. High‐fat diet (HFD)–induced obese C57BL/6J mice established administered with combinations CAVA‐G 6 weeks. trajectory mice's body weights was analyzed. Besides, hematoxylin eosin (HE) staining liver oil red O adipose tissue performed. ELISA assay employed measure serum levels total cholesterol (TC), triglyceride (TG), low‐density lipoprotein (LDL‐C), high‐density (HDL‐C). Moreover, metabolic profiling conducted through UPLC‐Q‐TOF/MS analysis. Gut microbiota analysis performed via 16S rRNA gene sequencing. Pattern recognition Pearson correlation pinpoint key endogenous metabolites microbiota. Two groups combination treatment (C3 A1) significantly prevented increase weight mice. According our analysis, best effect achieved when 37:63. TC LDL‐C dramatically decreased C3 group, whereas level TG reduced A1 group. Interestingly, HDL‐C increased Compared model a 16 25 biomarkers identified A1, respectively. These mainly implicated lipid metabolism primary bile acid biosynthesis. abnormal diversity gut induced HFD feeding. Treatment or relative abundance Akkermansia Novosphingobium , while reducing Dorea Bacteroides Roseburia . Of note, this is first report involved findings will layer foundation usage

Language: Английский

Citations

0

Rose Petal Extract Ameliorates Obesity in High Fat Diet-Induced Obese Mice DOI
Jaeeun Jung, Minhee Lee,

Seong-Hoo Park

et al.

Preventive Nutrition and Food Science, Journal Year: 2024, Volume and Issue: 29(2), P. 125 - 134

Published: June 28, 2024

In Asia,

Language: Английский

Citations

3

Dysregulation of lipid metabolism in chronic kidney disease and the role of natural products DOI

Yang-Yi Jiang,

Xiaoli Jiang, Haining Yu

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2024, Volume and Issue: 398(1), P. 261 - 278

Published: Aug. 20, 2024

Language: Английский

Citations

0

Eriodictyol regulates white adipose tissue browning and hepatic lipid metabolism in high fat diet-induced obesity mice via activating AMPK/SIRT1 pathway DOI

Song-Xia Lin,

Xiaoyi Li,

Qi-Cong Chen

et al.

Journal of Ethnopharmacology, Journal Year: 2024, Volume and Issue: 337, P. 118761 - 118761

Published: Aug. 30, 2024

Language: Английский

Citations

0