Environmental Toxicology and Pharmacology,
Journal Year:
2023,
Volume and Issue:
104, P. 104307 - 104307
Published: Nov. 1, 2023
The
present
study
aimed
to
quantify
the
concentration
levels
of
potentially
toxic
elements
(PTEs)
such
as
aluminum,
arsenic,
cadmium,
chromium,
copper,
nickel,
lead,
zinc,
and
mercury,
well
microplastics
occurrence
in
various
tissues
fish
seafood
species,
commercialized
Lower
Danube
River
Basin.
A
health
risk
assessment
analysis
was
performed
based
on
PTEs
muscle
tissue.
Estimated
daily
intake
(EDI),
target
hazard
quotient
(THQ),
index
(HI),
cancer
(TR)
were
calculated.
It
observed
that
species
within
category
registered
highest
PTEs.
For
instance,
tissue
bivalve
Mytilus
galloprovincialis
(from
Black
Sea),
value
case
Zn
(37.693
mg/kg),
presence
polystyrene
polymer
identified.
values
associated
with
EDI,
THQ,
HI,
TR
PTE
exposure
significantly
lower
than
1.
Environmental Toxicology and Pharmacology,
Journal Year:
2023,
Volume and Issue:
98, P. 104068 - 104068
Published: Jan. 19, 2023
Microplastic
(MP)
and
heating
(T)
suspected
to
modulate
biological
effects
of
aquatic
contaminants.
Salinomycin
(Sal)
is
veterinary
antibiotic
anticancer
agent.
The
goal
this
study
was
examine
the
multistress
effect
MP,
Sal
T
on
bioindicator
bivalve
mollusc.
Unio
tumidus
were
treated
with
MP
(1
mg
L-1),
(0.6
µg
their
combination
under
18°
C
(Mix)
25°
(MixT)
for
14
days.
digestive
glands
analyzed.
did
not
cause
changes
Mn-
Cu,Zn-SOD,
lipid
peroxidation
Cyp-450-depended
EROD
levels,
whereas
catalase,
GST
protein
carbonyls
(Sal-group)
increased
compared
control.
In
Mix-group,
enzymes,
particularly
(by
34%
115%
respectively)
up-regulated.
However,
in
MixT-group,
they
corresponding
control
or
lesser
(EROD,
catalase).
Our
findings
emphasize
need
take
into
account
interactions
environmental
risk
assessment.
The Science of The Total Environment,
Journal Year:
2023,
Volume and Issue:
890, P. 164075 - 164075
Published: May 23, 2023
Caffeine
(Caff)
is
one
of
the
most
widely
used
substances
in
human
diet
and
a
well-recognized
drug.
Its
input
into
surface
waters
remarkable,
but
biological
effects
on
aquatic
organisms
are
unclear,
particularly
combination
with
pollutants
suspected
modulatory
activity,
like
microplastics
(MP).
The
aim
this
study
was
to
reveal
impact
marine
mussel
Mytilus
galloprovincialis
(Lamark,
1819)
Caff
(20.0
μg
L-1)
environmentally
relevant
(Mix)
MP
1
mg
L-1
(size
35-50
μm)
after
exposure
for
14
days.
Untreated
exposed
separately
groups
were
also
examined.
Cell
viability
cell
volume
regulation
hemocytes
digestive
cells,
as
well
indexes
oxidative
stress,
glutathione
(GSH/GSSG)
metallothioneins
levels,
caspase-3
activity
gland
assessed.
Mix
reduced
Mn-superoxide
dismutase,
catalase,
S-transferase
activities
level
lipid
peroxidation,
increased
viability,
GSH/GSSG
ratio
(by
1.4-1.5-fold),
their
Zn
content,
while
did
not
affect
stress
metallothionein-related
chelation.
Protein
carbonyls
targeted
all
exposures.
distinguishing
feature
group
decline
(2-fold)
low
viability.
multi-stress
effect
shown
by
worsening
cells
confirmed
discriminant
analysis
biochemical
indexes.
special
capabilities
M.
sentinel
organism
make
it
an
excellent
bio-indicator
reflecting
sub-chronic
exposures
potentially
harmful
substances.
identification
modulation
individual
combined
increases
need
base
monitoring
programs
studies
Ecological Indicators,
Journal Year:
2023,
Volume and Issue:
155, P. 111058 - 111058
Published: Oct. 7, 2023
Microplastics
(MPs),
which
are
small
plastic
particles
measuring
less
than
5
mm
in
size,
have
emerged
as
a
significant
environmental
concern
marine
ecosystems
worldwide.
The
presence
of
MPs
aquatic
environments
has
increased
due
to
the
contributions
from
anthropogenic
and
terrestrial
sources,
raising
concerns
about
their
abundance
organisms.
primarily
originate
photo-degradation
larger
debris
(macroplastics),
with
release
into
environment
often
occurring
through
breakdown
additive
compounds.
ingestion
poses
eco-toxicological
risks
organisms,
causing
damage
gastrointestinal
(GI)
tracts
stomachs
affected
Approximately
80
%
can
be
classified
either
primary
such
those
generated
during
production
skincare
products,
tires,
use
carriers
for
pharmaceutical
or
secondary
sources
resulting
improper
disposal
plastics
near
coastal
areas
water
bodies.
issue
potential
effects
on
ecosystem
demands
attention.
In
conclusion,
this
review
provides
comprehensive
overview
vulnerability
microplastics
environments,
consolidating
current
understanding
distribution,
fate,
ecological
impacts.
It
emphasizes
urgent
need
ongoing
research
proactive
measures
mitigate
long-term
consequences
microplastic
pollution
essential
services
they
provide.
Chemosphere,
Journal Year:
2023,
Volume and Issue:
345, P. 140478 - 140478
Published: Oct. 19, 2023
This
study
investigated
the
toxicity
of
polyethylene
microplastics
(MPs;
<0.02
mm)
and
CuSO4,
alone
in
combination,
on
freshwater
crayfish
Pontastacus
leptodactylus.
In
this
study,
were
exposed
to
PE-MPs
(0.0,
0.5,
1
mg
L-1)
CuSO4·5H2O
for
a
period
28
days.
Next,
multi-biomarkers,
including
biochemical,
immunological,
oxidative
stress
indicators
analyzed.
Results
showed
that
co-exposure
CuSO4
resulted
increased
aspartate
aminotransferase
(AST),
alanine
(ALT),
lactate
dehydrogenase
(LDH),
decreased
alkaline
phosphatase
(ALP),
butyrylcholinesterase
(BChE),
gamma-glutamyl-transferase
(GGT).
Triglycerides,
cholesterol,
glucose,
albumin
content
also
increased.
Although
no
significant
change
was
observed
lysozyme
phenoloxidase
activities
co-exposed
0.5
L-1
MPs
their
significantly
other
experimental
groups.
Oxidative
parameters
hepatopancreas
indicated
superoxide
dismutase
(SOD),
glutathione
peroxidase
(GPx),
malondialdehyde
(MDA)
levels,
but
catalase
(CAT),
glucose
6-phosphate
(G6PDH),
cellular
total
antioxidant
(TAC).
sub-chronic
confirmed.
The
confirmed
found
higher
concentrations
led
more
severe
effects.
Co-exposure
primarily
compromised
endpoints,
showing
when
both
pollutants
present
concentrations.
POX,
LYZ,
ALP,
GGT,
LDH,
CAT
suppressed
by
MPs.
However,
synergistic
increase
measured
biomarkers
The Science of The Total Environment,
Journal Year:
2024,
Volume and Issue:
918, P. 170568 - 170568
Published: Feb. 2, 2024
Among
personal
care
products,
quaternium-15
is
prominently
featured
as
a
preservative
in
items
such
shampoos,
soaps,
shaving
and
cosmetics.
The
widespread
use
of
these
products
people's
daily
routines
contributes
to
release
into
aquatic
ecosystems.
In
this
context,
the
primary
aim
study
was
assess
physiological
cellular
responses
digestive
gland
gills
Mytilus
galloprovincialis
exposure.
Cell
viability
ability
cells
regulate
their
volume
were
evaluated.
Additionally,
expression
genes
involved
oxidative
stress
response
assessed
further
substantiate
compound's
harmful
effects.
Results
indicated
significant
decrease
both
RVD
(regulatory
decrease)
capacity
when
exposed
hypotonic
solution.
Furthermore,
impairment
cell
function
corroborated
by
modulation
stress-related
gene
expression,
including
SOD,
Cat,
well
Hsp70
CYP4Y1.
Similar
alterations
observed
gills,
reflecting
impaired
functionality
vital
organ
well.
summary,
outcomes
provide
conclusive
evidence
toxicity
quaternium-15.
This
underscores
urgent
need
investigate
toxicological
effects
contaminant
on
ecosystems
emphasises
necessity
limiting
containing
Reviews in Aquaculture,
Journal Year:
2021,
Volume and Issue:
14(2), P. 1028 - 1045
Published: Nov. 22, 2021
Abstract
Microplastics
(MPs),
antibiotics
and
heavy
metals
unavoidably
contaminate
the
aquaculture
environment,
with
serious
ecological
human
health
consequences.
Antibiotic‐resistance
genes
(ARGs)
metal
resistance
(MRGs)
are
induced
in
microorganisms
environment
as
a
defence
mechanism
against
respectively.
Furthermore,
will
cause
bacteria
to
employ
antibiotic
through
co‐selection
(co‐resistance
or
cross‐resistance)
other
potential
mechanisms.
MPs
may
also
act
carriers
of
multidrug
environments
because
they
hotspots
for
enrichment
transmission
resistance.
Multidrug‐resistant
(MDR)
infiltrate
aquatic
organisms
via
food
chain
(eg
MDR‐microorganisms→myctophids→
tuna/
squid/
whales/
seabirds/
seals),
after
long‐term
enrichment,
gain
access
body,
posing
major
risk
health.
As
result,
this
review
article
summarises
contamination
MPs,
global
settings;
discusses
generation
ARGs,
MRGs
common
selection
mechanisms
development
emphasises
role
hot
spots
antibiotic‐resistance
selective
well
multi‐drug‐resistant
(MDRGs),
an
increasing
threat
even
