Environmental Science & Technology,
Journal Year:
2023,
Volume and Issue:
57(14), P. 5782 - 5793
Published: March 29, 2023
The
placenta
is
pivotal
for
fetal
development
and
maternal–fetal
transfer
of
many
substances,
including
per-
polyfluoroalkyl
substances
(PFASs).
However,
the
intraplacental
distribution
PFASs
their
effects
on
placental
vascular
function
remain
unclear.
In
this
study,
302
tetrads
matched
subchorionic
(fetal-side),
parabasal
(maternal-side),
cord
serum,
maternal
serum
samples
were
collected
from
Guangzhou,
China.
Eighteen
emerging
legacy
five
biomarkers
measured.
Results
showed
that
higher
levels
perfluorooctanoic
(PFOA),
perfluorooctane
sulfonic
acid
(PFOS),
chlorinated
polyfluorinated
ether
acids
(Cl-PFESAs)
detected
in
compared
to
placenta.
There
significant
associations
placenta,
but
not
with
(up
32.5%)
lower
birth
size.
Birth
weight
was
negatively
associated
PFOA
(β:
−103.8,
95%
CI:
−186.3
−21.32)
6:2
Cl-PFESA
−80.04,
−139.5
−20.61),
primarily
Mediation
altered
angiopoietin-2
endothelial
growth
factor
receptor-2
evidenced
adverse
outcomes
PFOS
8:2
Cl-PFESA,
explaining
9.5%–32.5%
total
effect.
To
best
our
knowledge,
study
first
report
differential
mediating
provides
novel
insights
into
plate-specific
measurement
PFAS-associated
health
risk
assessment.
The Science of The Total Environment,
Journal Year:
2022,
Volume and Issue:
845, P. 157255 - 157255
Published: July 8, 2022
Per
and
Polyfluoroalkyl
Substances
(PFAS)
are
a
diverse
group
of
man-made
chemicals
with
range
industrial
applications
which
widespread
in
the
environment.
They
structurally
but
comprise
common
chemical
feature
at
least
one
(though
usually
more)
perfluorocarbon
moiety
(-CnF2n-)
attached
to
functional
such
as
carboxylic
or
sulphonic
acid.
The
strength
Carbon-Fluorine
bond
means
compounds
do
not
break
down
easily
can
thus
bioaccumulate.
PFAS
high
concern
regulators
public
due
their
potential
toxicity
persistence.
At
exposure
levels,
have
been
implicated
harmful
effects
on
human
environmental
health,
particularly
problems
in/with
development,
cholesterol
endocrine
disruption,
immune
system
function,
oncogenesis.
However,
most
toxicology
studies
use
far
higher
levels
than
generally
found
Additionally,
since
type
exposure,
used,
organisms
tested
all
vary
between
studies,
so
results.
Traditional
ecotoxicology
may
identify
environmentally
relevant
exposures.
Here
we
conduct
review
omics-based
using
laboratory
ecotoxicological
methodologies
show
that
biochemical
response
pathways
identified
multiple
studies.
A
major
pathway
was
pentose
phosphate
shunt
pathway.
Such
molecular
markers
sublethal
will
greatly
benefit
accurate
effective
risk
assessments
ensure
new
regulations
consider
full
health
receptors.
Sustainability,
Journal Year:
2023,
Volume and Issue:
15(23), P. 16173 - 16173
Published: Nov. 21, 2023
Per
and
polyfluoroalkyl
substances
(PFAS)
have
been
extensively
employed
in
a
broad
range
of
manufacturing
consumer
goods
due
to
their
highly
persistent
nature.
PFAS
exposure
is
recognized
pose
serious
health
hazards;
therefore,
addressing
pollution
water
has
become
top
priority
for
public
environmental
protection
organizations.
This
review
article
focuses
on
the
efficiency
different
removal
techniques
(activated
carbon,
biochar,
ion
exchange
resin,
membrane
filtration,
reverse
osmosis,
metal-organic
frameworks,
foam
fractionation,
ozone
destruction
techniques)
eliminating
types
short-
long-chain
from
water.
Hydrophobicity
electrostatic
interactions
are
revealed
be
primary
mechanisms
elimination
PFAS.
The
all
eradicate
short-chain
comparatively
lower
compared
most
efficient
but
some
drawbacks,
including
formation
precursors
high
operational
costs.
According
findings
study,
it
anticipated
that
combined
methods
will
required
effectively
remediate
PFAS-contaminated
The Journal of Physical Chemistry C,
Journal Year:
2023,
Volume and Issue:
127(6), P. 3204 - 3216
Published: Feb. 3, 2023
A
strategy
that
can
be
used
to
develop
metal–organic
frameworks
(MOFs)
capture
per-
and
poly-fluoroalkyl
substances
(PFAS)
from
water
is
functionalizing
them
with
fluorine
moieties.
We
investigated
different
fluorine-functionalization
strategies
their
performance
in
removing
PFAS
using
molecular
simulations.
Perfluorooctanoic
acid
(PFOA),
one
of
the
most
widely
encountered
sources,
was
as
probe
molecule.
Our
simulations
show
functionalization
by
incorporating
fluorinated
anions
bridging
ligands
MOFs
creates
additional
binding
sites
for
PFOA;
however,
same
also
attract
molecules,
which
casts
doubt
on
potential
use.
In
contrast,
trifluoromethyl
or
substitution
MOF
results
higher
hydrophobicity.
However,
pores
this
method
should
have
optimum
size
accommodate
PFOA.
Likewise,
post-synthetic
through
grafting
perfluorinated
alkanes
showed
increased
PFOA
affinity.
Fluorine-functionalized
high
hydrophobicity
optimized
pore
sizes
effectively
at
very
low
concentrations
Lubricants,
Journal Year:
2024,
Volume and Issue:
12(4), P. 114 - 114
Published: March 29, 2024
Per-
and
polyfluoroalkyl
substances
(PFAS),
also
known
as
forever
chemicals,
exhibit
exceptional
chemical
stability
resistance
to
environmental
degradation
thanks
their
strong
C-F
bonds
nonpolar
nature.
However,
widespread
use
persistence
have
a
devastating
impact
on
the
environment.
This
review
examines
roles
of
PFAS
in
tribological
applications,
specifically
lubricants
lubricating
systems.
article
focuses
conventional
advanced
lubricants,
including
ionic
liquids
(ILs)
modern
automotive
vehicles.
The
objective
this
paper
is
provide
comprehensive
overview
adverse
impacts
whilst
acknowledging
outstanding
performance
surface
coatings,
composite
materials,
additives
oils
greases.
pathways
through
which
are
introduced
into
environment
via
systems
such
seals
O-rings
identified,
alongside
subsequent
dispersion
routes
interfaces
across
they
interact.
Furthermore,
we
examine
toxicological
implications
exposure
terrestrial
aquatic
life
forms,
plants,
animals,
humans,
along
with
ecological
consequences
bioaccumulation
biomagnification
trophic
levels
ecosystems.
ends
potential
remediation
strategies
for
use,
treatment
technologies,
biodegradation,
recovery
recycling
methods,
search
more
environmentally
benign
alternatives.
