Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 150, P. 104597 - 104597
Published: June 15, 2024
Language: Английский
Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 150, P. 104597 - 104597
Published: June 15, 2024
Language: Английский
Heliyon, Journal Year: 2023, Volume and Issue: 9(3), P. e13986 - e13986
Published: Feb. 24, 2023
Pesticide usage has increased to fulfil agricultural demand. Pesticides such as organophosphorus pesticides (OPPs) are ubiquitous in world food production. Their widespread unavoidable detrimental consequences for humans, wildlife, water, and soil environments. Hence, the development of more convenient efficient pesticide residue (PR) detection methods is paramount importance. Visual detecting approaches have acquired a lot interest among different sensing systems due inherent advantages terms simplicity, speed, sensitivity, eco-friendliness. Furthermore, various detections been proven enable real-life PR surveillance environment water. Fluorometric (FL), colourimetric (CL), enzyme-inhibition (EI) techniques emerged viable options. These technologies do not need complex operating processes or specialist equipment, simple colour change allows visual monitoring result. on-site water environments discussed this paper. This paper further reviews prior research on integration CL, FL, EI-based with nanoparticles (NPs), quantum dots (QDs), metal-organic frameworks (MOFs). Smartphone PRs also reviewed. Finally, conventional nanoparticle (NPs) based strategies compared.
Language: Английский
Citations
29Angewandte Chemie International Edition, Journal Year: 2023, Volume and Issue: 62(50)
Published: Nov. 3, 2023
Chemo-dynamic therapy (CDT) based on the Fenton or Fenton-like reaction has emerged as a promising approach for cancer treatment. However, autophagy-mediated self-protection mechanisms of cells pose significant challenge to efficacy CDT. Herein, we developed metal-DNA nanocomplexes (DACs-Mn) enhance CDT via DNAzyme inhibition autophagy. Specifically, Mn-based catalyst in DACs-Mn was used generate highly hydroxyl radicals (⋅OH) that kill cells, while ATG5 incorporated into inhibited expression autophagy-associated proteins, thereby improving By disrupting self-protective pathway under severe oxidative stress, this novel found synergistically both vitro and vivo models, effectively amplifying tumor-specific damage. Notably, Metal-DNA can also induce immunogenic cell death (ICD), inhibiting tumor metastasis. bilateral model mice, combined autophagy followed by immune checkpoint blockade shown potential effective treatment modality primary metastatic tumors.
Language: Английский
Citations
28Analytica Chimica Acta, Journal Year: 2023, Volume and Issue: 1286, P. 342045 - 342045
Published: Nov. 20, 2023
Language: Английский
Citations
28Food Chemistry, Journal Year: 2024, Volume and Issue: 447, P. 139020 - 139020
Published: March 15, 2024
Language: Английский
Citations
14Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 150, P. 104597 - 104597
Published: June 15, 2024
Language: Английский
Citations
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