Chemical Reviews,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 10, 2024
Transition
metals
function
as
structural
and
catalytic
cofactors
for
a
large
diversity
of
proteins
enzymes
that
collectively
comprise
the
metalloproteome.
Metallostasis
considers
all
cellular
processes,
notably
metal
sensing,
metalloproteome
remodeling,
trafficking
(or
allocation)
ensure
functional
integrity
adaptability
Bacteria
employ
both
protein
RNA-based
mechanisms
sense
intracellular
transition
bioavailability
orchestrate
systems-level
outputs
maintain
metallostasis.
In
this
review,
we
contextualize
metallostasis
by
briefly
discussing
specialized
roles
play
in
biology.
We
then
offer
comprehensive
perspective
on
metalloregulatory
metal-sensing
riboswitches,
defining
general
principles
within
each
sensor
superfamily
capture
how
specificity
is
encoded
sequence,
selectivity
can
be
leveraged
downstream
synthetic
biology
biotechnology
applications.
This
followed
discussion
recent
work
highlights
selected
outputs,
including
remodeling
allocation
metallochaperones
to
client
compartments.
close
places
where
more
needed
fill
gaps
our
understanding
Bioengineered,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: Feb. 1, 2024
The
burden
of
food
contamination
and
wastage
has
significantly
contributed
to
the
increased
prevalence
foodborne
disease
insecurity
all
over
world.
Due
this,
there
is
an
urgent
need
develop
a
smarter
traceability
system.
Recent
advancements
in
biosensors
that
are
easy-to-use,
rapid
yet
selective,
sensitive,
cost-effective
have
shown
great
promise
meet
critical
demand
for
onsite
immediate
diagnosis
treatment
safety
quality
control
(i.e.
point-of-care
technology).
This
review
article
focuses
on
recent
development
different
monitoring.
In
general,
application
agriculture
pre-harvest
stage)
early
detection
routine
plant
infections
or
stress
discussed.
Afterward,
more
detailed
advancement
past
five
years
within
supply
chain
post-harvest
detect
types
contaminants
smart
packaging
highlighted.
A
section
discusses
perspectives
future
also
mentioned.
Materials Advances,
Journal Year:
2024,
Volume and Issue:
5(9), P. 3563 - 3586
Published: Jan. 1, 2024
Sustainability
is
a
priority
of
researchers
in
designing
and
manufacturing
biosensing
devices
current
research
activities.
Paper-based
multifunctional
biosensors
are
widely
developed
for
different
applications
to
realize
sustainable
future.
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(8), P. 10805 - 10812
Published: Feb. 21, 2024
Utilizing
the
mercury
(Hg2+)-triggered
deprotection
of
thioacetals
to
aldehyde
groups,
we
constructed
a
water-soluble
triphenylamine
(TPA)-based
polythioacetal
PTA-TPA
with
thioacetal
groups
in
backbones
for
efficient
sensing
Hg2+
aqueous
solutions.
is
conveniently
prepared
by
polycondensation
3,
6-dioxa-1,8-octanedithiol
(DODT)
4-(N,N-diphenylamino)
benzaldehyde
(TPA-CHO)
using
thiol-terminated
mPEG2k-SH
as
capping
agent.
The
interaction
activates
aggregation-induced
emission
(AIE)
process
TPA-CHO
molecules,
which
makes
enhanced,
and
color
changes
sky
blue,
while
other
metal
ions
do
not
interfere
process.
can
be
used
highly
selective
ultrafast
detection
system
low
limit
(LOD)
9.88
nM
fast
response
less
than
1
min.
In
addition,
test
strips
report
presence
an
LOD
×
10–5
M.
Intracellular
imaging
applications
have
demonstrated
that
acts
biocompatible
fluorescent
probe
HeLa
cells.
Overall,
fluorescence
probes
characteristics
easy
synthesis,
cost-effective,
speed,
high
selectivity,
sensitivity,
practical
applications.
Comprehensive Reviews in Food Science and Food Safety,
Journal Year:
2024,
Volume and Issue:
23(5)
Published: Aug. 13, 2024
Abstract
Food
safety
and
authenticity
analysis
play
a
pivotal
role
in
guaranteeing
food
quality,
safeguarding
public
health,
upholding
consumer
trust.
In
recent
years,
significant
social
progress
has
presented
fresh
challenges
the
realm
of
analysis,
underscoring
imperative
requirement
to
devise
innovative
expedient
approaches
for
conducting
on‐site
assessments.
Consequently,
cellulose
paper‐based
devices
(PADs)
have
come
into
spotlight
due
their
characteristics
microchannels
inherent
capillary
action.
This
review
summarizes
advances
PADs
various
products,
comprising
fabrication
strategies,
detection
methods
such
as
mass
spectrometry
multi‐mode
detection,
sampling
processing
considerations,
well
applications
screening
factors
assessing
developed
past
3
years.
According
above
studies,
face
limited
sample
processing,
inadequate
multiplexing
capabilities,
workflow
integration,
while
emerging
innovations,
use
simplified
pretreatment
techniques,
integration
advanced
nanomaterials,
instruments
portable
spectrometer
innovation
multimodal
methods,
offer
potential
solutions
are
highlighted
promising
directions.
underscores
facilitating
decentralized,
cost‐effective,
testing
methodologies
maintain
standards.
With
progression
interdisciplinary
research,
expected
become
essential
platforms
authentication
thereby
significantly
enhancing
global
consumers.
