Quantitative association of SARS-CoV-2 in wastewater and clinically confirmed cases in different areas of the Tokyo 2020 Olympic and Paralympic Village

The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 960, P. 178209 - 178209

Published: Jan. 1, 2025

International mass gathering events, such as the Olympic and Paralympic Games, face risk of cross-border transmission infectious diseases. We previously reported that wastewater-based epidemiology (WBE), which has attracted attention a COVID-19 surveillance tool, was implemented in Tokyo 2020 Village to gain comprehensive understanding incidence village. In present study, we explored quantitative association wastewater viral load clinically confirmed cases various areas From July 14 through September 8, 2021, 360 passive samples 329 grab were collected from seven distinct within village manholes examined for SARS-CoV-2 RNA by Efficient Practical virus Identification System with Enhanced Sensitivity (EPISENS) methods. The detection rates showed significant (P < 0.001, φ = 0.32, chi-square test), sampling showing higher positive rate. Based on Receiver Operating Characteristic (ROC) curve analysis cases, most sensitive cutoff point judged be limit quantification (LOQ) three-day samples. Under this optimal condition, sensitivity specificity 0.78 0.40, respectively. study demonstrated effectiveness building-level based cases. Wastewater can powerful tool monitor diseases among temporary residents, tourists participants international provided proper analytical methods are employed.

Language: Английский

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Environmental Dissemination of SARS-CoV-2: An Analysis Employing Crassphage and Next-Generation Sequencing Protocols

Food and Environmental Virology, Journal Year: 2025, Volume and Issue: 17(1)

Published: Jan. 7, 2025

Language: Английский

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Lifting of travel restrictions brings additional noise in COVID-19 surveillance through wastewater-based epidemiology in post-pandemic period

Water Research, Journal Year: 2025, Volume and Issue: 274, P. 123114 - 123114

Published: Jan. 7, 2025

The post-pandemic world still faces ongoing COVID-19 infections, although international travel has returned to pre-pandemic conditions. Wastewater-based epidemiology (WBE) is considered an efficient tool for the population-wide surveillance of infections during pandemic. However, performance WBE in era with restrictions lifted remains unknown. Utilizing weekly county-level wastewater data from June 2021-November 2022 222 counties 49 states (covering 104 million people) United States America, we retrospectively evaluated correlations between SARS-CoV-2 RNA (C

Language: Английский

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Localised wastewater SARS-CoV-2 levels linked to COVID-19 cases: A long-term multisite study in England

The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 962, P. 178455 - 178455

Published: Jan. 1, 2025

Wastewater-based surveillance (WBS) can monitor for the presence of human health pathogens in population. During COVID-19, WBS was widely used to determine wastewater SARS-CoV-2 RNA concentration (concentrations) providing information on community COVID-19 cases (cases). However, studies examining relationship between concentrations and tend be localised or focussed small-scale institutional settings. Few have examined this multiple settings, over long periods, with large sample numbers, nor attempted quantify detail how catchment characteristics affected these. This 18-month study (07/20-12/21) explored correlation quantitative using censored regression. Our analysis >94,000 samples collected from 452 diverse sampling sites (259 Sewage Treatment Works (STW) 193 Sewer Network Sites (SNS)) covering ~65 % English Wastewater were linked ~6 million diagnostically confirmed cases. High coefficients found (STW: median r = 0.66, IQR: 0.57-0.74; SNS: 0.65, 0.54-0.74). The (regression coefficient) variable catchments. Catchment (e.g. size population grab vs automated sampling) had significant but small effects regression coefficients. last six months reduced became highly coincided a shift towards younger cases, vaccinated rapid emergence variant Omicron. programme rapidly introduced at scale during COVID-19. Laboratory methods evolved catchments characteristics. Despite diversity, findings indicate that provides an effective proxy establishing dynamics across wide variety communities. While there is potential predicting concentration, may more smaller scales.

Language: Английский

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Modelling COVID-19 epidemic curve in Taipei City, Taiwan by a Citywide Wastewater SARS-CoV-2 Surveillance

Journal of Hazardous Materials Advances, Journal Year: 2025, Volume and Issue: unknown, P. 100635 - 100635

Published: Feb. 1, 2025

Language: Английский

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