Enzyme-assisted patulin detoxification: Recent applications and perspectives

Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 146, P. 104383 - 104383

Published: Feb. 18, 2024

Language: Английский

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Identification and application of a novel patulin degrading enzyme from Cyberlindnera fabianii

Food Research International, Journal Year: 2024, Volume and Issue: 192, P. 114846 - 114846

Published: July 27, 2024

Language: Английский

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Drug repurposing for diabetes mellitus: In silico and in vitro investigation of DrugBank database for α-glucosidase inhibitors

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 270, P. 132164 - 132164

Published: May 9, 2024

Language: Английский

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Unraveling the effective inhibition of α-terpinol and terpene-4-ol against Aspergillus carbonarius: Antifungal mechanism, ochratoxin A biosynthesis inhibition and degradation perspectives

Food Research International, Journal Year: 2024, Volume and Issue: 194, P. 114915 - 114915

Published: Aug. 13, 2024

Aspergillus carbonarius, a common food-contaminating fungus, produces ochratoxin A (OTA) and poses risk to human health. This study aimed assess the inhibitory activity of tea tree essential oil its main components, Terpene-4-ol (T4), α-terpineol (αS), 3-carene (3C) against A. carbonarius. The showed αS T4 were antifungal components oil, which primarily inhibit carbonarius growth through cell membrane disruption, reducing antioxidant enzyme activities (catalase, peroxidase, superoxide dismutase) interrupting tricarboxylic acid cycle. Furthermore, interacted with enzymes related OTA biosynthesis. Molecular docking molecular dynamics show that they bound mainly P450 minimum binding energy -7.232 kcal/mol, we infered blocking synthesis precursor OTβ. Our hypothesis was preliminarily verified by detection key substances in pathway. results UHPLC-QTOF-MS

Language: Английский

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Functional characterization and structural basis of an efficient ochratoxin A-degrading amidohydrolase

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 278, P. 134831 - 134831

Published: Aug. 18, 2024

Language: Английский

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Efficient Expression and Activity Optimization of Manganese Peroxidase for the Simultaneous Degradation of Aflatoxins AFB₁, AFB₂, AFG₁, and AFG₂

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 3, 2025

Aflatoxins (AFs), notorious mycotoxins that pose significant risks to human and animal health, make biodegradation extremely crucial as they offer a promising approach managing reducing their harmful impacts. In this study, we identified manganese peroxidase from

Language: Английский

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Integrated omics analyses elucidate acetaminophen biodegradation by Enterobacter sp. APAP_BS8

Journal of Environmental Management, Journal Year: 2025, Volume and Issue: 375, P. 124215 - 124215

Published: Jan. 21, 2025

Language: Английский

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Mechanism of patulin biodegradation by a reductase from Saccharomyces cerevisiae and its potential application to apple juice

Food Research International, Journal Year: 2025, Volume and Issue: 206, P. 116066 - 116066

Published: Feb. 25, 2025

Language: Английский

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Identification and characterization of aldo-keto reductase responsible for patulin degradation in Saccharomyces cerevisiae

Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 143706 - 143706

Published: March 1, 2025

Language: Английский

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Nucleic Acid Cascade Amplification Empowered Self-Powered Sensing Platform Based on the Confined Bioconjugate Catalysis Strong Redox Boosting Mechanism

Published: Jan. 1, 2025

Language: Английский

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