Mn-ZIF nanozymes kill tumors by generating hydroxyl radical as well as reversing the tumor microenvironment DOI Creative Commons
Jiyu Han,

Hairong Ma,

Songtao Ai

et al.

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 13, 2024

Tumor tissues are well known for their unique high hydrogen peroxide (H 2 O ) microenvironment. How to exploit this tumor microenvironment cell killing is a question. In study, Mn-doped metal-organic framework (Mn-ZIF) was constructed. It possesses good peroxidase (POD) activity, which can oxidize tumor-localized H into hydroxyl radicals (·OH), that the ability directly kill cells. More surprisingly, in vivo experiments researchers not only observed tumor-killing effect of Mn-ZIF, but also found it changes macrophage phenotype region. There an increase polarization towards M1 subtype. This suggests Mn-ZIF comes from its POD regulates immune conclusion, preparation provides new way comprehensive therapy.

Language: Английский

Nickel-based dual single atom electrocatalysts for the nitrate reduction reaction DOI
Cuizhu Ye, Ziyi Guo, Yongfang Zhou

et al.

Journal of Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 677, P. 933 - 941

Published: Aug. 16, 2024

Citations

4
The effect of two critical operating factors on the enhanced catalytic conversion of aqueous NO3– to NH4+ by Pt-Co@NC and theoretical verification of its surface reaction mechanism DOI Creative Commons
Nurbek Nurlan, Jaewoo Jeong, Meiirzhan Nurmyrza

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159874 - 159874

Published: Jan. 1, 2025

Language: Английский

Citations

0
Recent advances in metal single−atom catalysts for ammonia electrosynthesis DOI
Zhan Lu, Jijie Zhang, Yuting Wang

et al.

Materials Horizons, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

This review provides insight into the development of advanced metal single-atom catalysts for ammonia electrosynthesis.

Language: Английский

Citations

0
Heterostructured Sn/Co oxides for electrocatalytic reduction of nitrate to ammonia DOI

Yinjun Ran,

Tianhao Li,

Chenghuan Zhong

et al.

Journal of Alloys and Compounds, Journal Year: 2025, Volume and Issue: unknown, P. 180522 - 180522

Published: April 1, 2025

Language: Английский

Citations

0
Electrochemically nitrate remediation by single-atom catalysts: advances, mechanisms, and prospects DOI Open Access
Zhe Li,

Chuanju Yang,

Bin Xu

et al.

Energy Materials, Journal Year: 2024, Volume and Issue: 4(4), P. 400046 - 400046

Published: Jan. 1, 2024

Electrocatalytic nitrate reduction reaction (NITRR) is highly desirable for remediating (NO3-) pollution and producing ammonia (NH3) under mild conditions. To date, great efforts have been made to fabricate selective, efficient, stable electrocatalysts NITRR. Among the numerous strategies, single-atom catalysts (SACs) received extensive interest investigations due their cost-effective maximum atomic utilization. However, further development of SACs-based NITRR remains hindered by a poor understanding in-depth mechanisms. Consequently, this review summarizes recent advances SACs NITRR, including Cu-SACs, Fe-SACs, Zn-SACs, Co-SACs, alloys. In addition, characterization techniques pathways are presented give robust Finally, we analyze current challenges in fabricating while key factors improving performances also examined.

Language: Английский

Citations

1
Nitrate reduction to nitrogen in wastewater using mesoporous carbon encapsulated Pd–Cu nanoparticles combined with in-situ electrochemical hydrogen evolution DOI

Wenlue Cai,

Chen Chen, Chenyu Bao

et al.

Journal of Environmental Management, Journal Year: 2024, Volume and Issue: 362, P. 121346 - 121346

Published: June 1, 2024

Language: Английский

Citations

0
Mn-ZIF nanozymes kill tumors by generating hydroxyl radical as well as reversing the tumor microenvironment DOI Creative Commons
Jiyu Han,

Hairong Ma,

Songtao Ai

et al.

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 13, 2024

Tumor tissues are well known for their unique high hydrogen peroxide (H 2 O ) microenvironment. How to exploit this tumor microenvironment cell killing is a question. In study, Mn-doped metal-organic framework (Mn-ZIF) was constructed. It possesses good peroxidase (POD) activity, which can oxidize tumor-localized H into hydroxyl radicals (·OH), that the ability directly kill cells. More surprisingly, in vivo experiments researchers not only observed tumor-killing effect of Mn-ZIF, but also found it changes macrophage phenotype region. There an increase polarization towards M1 subtype. This suggests Mn-ZIF comes from its POD regulates immune conclusion, preparation provides new way comprehensive therapy.

Language: Английский

Citations

0