Synergizing Ecotoxicology and Microbiome Data Is Key for Developing Global Indicators of Environmental Antimicrobial Resistance DOI Creative Commons
John Paul Makumbi, Samuel K. Leareng, Rian Pierneef

et al.

Microbial Ecology, Journal Year: 2024, Volume and Issue: 87(1)

Published: Nov. 29, 2024

Abstract The One Health concept recognises the interconnectedness of humans, plants, animals and environment. Recent research strongly supports idea that environment serves as a significant reservoir for antimicrobial resistance (AMR). However, complexity natural environments makes efforts at AMR public health risk assessment difficult. We lack sufficient data on key ecological parameters influence AMR, well primary proxies necessary evaluating risks to human health. Developing environmental ‘early warning systems’ requires models with well-defined parameters. This is support implementation clear targeted interventions. In this review, we provide comprehensive overview current tools used globally underlying knowledge gaps. highlight urgent need standardised, cost-effective frameworks are adaptable across different regions enhance comparability reliability. These must also account previously understudied sources, such horticulture, emerging threats like climate change. addition, integrating traditional ecotoxicology modern ‘omics’ approaches will be essential developing more informing mitigation strategies.

Language: Английский

Carbapenem-Resistant Pseudomonas aeruginosa’s Resistome: Pan-Genomic Plasticity, the Impact of Transposable Elements and Jumping Genes DOI Creative Commons
Theodoros Karampatakis, Katerina Tsergouli, Payam Behzadi

et al.

Antibiotics, Journal Year: 2025, Volume and Issue: 14(4), P. 353 - 353

Published: March 31, 2025

Pseudomonas aeruginosa, a Gram-negative, motile bacterium, may cause significant infections in both community and hospital settings, leading to substantial morbidity mortality. This opportunistic pathogen can thrive various environments, making it public health concern worldwide. P. aeruginosa’s genomic pool is highly dynamic diverse, with pan-genome size ranging from 5.5 7.76 Mbp. versatility arises its ability acquire genes through horizontal gene transfer (HGT) via different genetic elements (GEs), such as mobile (MGEs). These MGEs, collectively known the mobilome, facilitate spread of encoding resistance antimicrobials (ARGs), heavy metals (HMRGs), virulence (VGs), metabolic functions (MGs). Of particular are acquired carbapenemase (ACGs) other β-lactamase genes, classes A, B [metallo-β-lactamases (MBLs)], D carbapenemases, which lead increased antimicrobial resistance. review emphasizes importance mobilome understanding aeruginosa.

Language: Английский

Citations

2

Antibiotic resistance genes in anaerobic digestion: Unresolved challenges and potential solutions DOI
Chunxiao Wang, Xiaole Yin, Xiaoqing Xu

et al.

Bioresource Technology, Journal Year: 2025, Volume and Issue: unknown, P. 132075 - 132075

Published: Jan. 1, 2025

Language: Английский

Citations

1

Visible light-assisted CoMoO₄/g-C₃N₄ photocatalyst for improved removal of antibiotic contaminants from wastewater DOI
Ji-Tae Kim, Nguyen Minh Viet, Hường Phạm Thị

et al.

Materials Chemistry and Physics, Journal Year: 2025, Volume and Issue: 334, P. 130433 - 130433

Published: Jan. 20, 2025

Language: Английский

Citations

1

Antibiotic resistance genes risks in relation to host pathogenicity and mobility in a typical hospital wastewater treatment process DOI
Chenye Xu, Chun Hu,

Fang Li

et al.

Environmental Research, Journal Year: 2024, Volume and Issue: 259, P. 119554 - 119554

Published: July 2, 2024

Language: Английский

Citations

5

Mapping antimicrobial resistance landscape at a city scale sewage network DOI Creative Commons
Clara Díaz-García, Miquel Sánchez‐Osuna, Albert Serra-Compte

et al.

The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 974, P. 179127 - 179127

Published: March 26, 2025

Language: Английский

Citations

0

A Review on the Prevalence and Treatment of Antibiotic Resistance Genes in Hospital Wastewater DOI Creative Commons

Lihua Lan,

Zhaoran Wang, Yuxin Chen

et al.

Toxics, Journal Year: 2025, Volume and Issue: 13(4), P. 263 - 263

Published: March 31, 2025

Antibiotic resistance is a global environmental and health threat. Approximately 4.95 million deaths were associated with antibiotic in 2019, including 1.27 that directly attributable to bacterial antimicrobial resistance. Hospital wastewater one of the key sources for spread clinically relevant genes (ARGs) into environment. Understanding current situation ARGs hospital great significance. Here, we review prevalence antibiotic-resistant bacteria (ARB) from other places treatment methods used. We further discuss intersection between COVID-19 during pandemic. This highlights issues dissemination critical It imperative implement more effective processes eliminate ARGs, particularly long period.

Language: Английский

Citations

0

Effective approach for removing antibiotic residues from wastewater using Bi 2 O 3 @C 3 N 4 photocatalyst DOI
Nguyen Minh Viet, Phong Nguyen Thanh, Nguyen Minh Phuong

et al.

Journal of Environmental Science and Health Part B, Journal Year: 2025, Volume and Issue: 60(3), P. 121 - 128

Published: Feb. 6, 2025

This study explores the photocatalytic decomposition of antibiotic residues, including tetracycline (TCR) and amoxicillin (AMR), from wastewater using Bi2O3@C3N4 photocatalyst. The characterization findings revealed that exhibited significantly improved light absorption properties enhanced charge separation efficiency. According to experimental results, high degradation efficiencies 77.6% for TCR 83.2% AMR in samples. It also displayed excellent reusability, with removal remaining at 71.3 78.8%, respectively, after five cycles. Additionally, photodegradation is suggested follow Z-scheme pathway. results this could be utilized removing pollutants wastewater, thereby reducing their impact on human health environment.

Language: Английский

Citations

0

Environmental High-Risk Efflux Pumps Mediate Concurrent Enhancement of Resistance and Virulence in Reclaimed Water from Urban Wastewater Treatment Plants DOI

Shanqi Shen,

Zhong Mao He,

Shaohua Zhao

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 493, P. 138236 - 138236

Published: April 16, 2025

Language: Английский

Citations

0

Feedstock-dependent antibiotic resistance gene patterns and expression profiles in industrial scale biogas plants revealed by meta-omics technology DOI Creative Commons
Roland Wirth, Prateek Shetty, Zoltán Bagi

et al.

Water Research, Journal Year: 2024, Volume and Issue: 268, P. 122650 - 122650

Published: Oct. 18, 2024

Language: Английский

Citations

3

First Report of Carbapenem-Resistant Klebsiella michiganensis Co-Harboring blaKPC-2 and TmexCD2-ToprJ2 Isolated from Wastewater at a Tertiary Hospital in Beijing DOI Creative Commons
Jason M. Long, Jiali Chen, Yue Yuan

et al.

Infection and Drug Resistance, Journal Year: 2024, Volume and Issue: Volume 17, P. 5117 - 5128

Published: Nov. 1, 2024

is an emerging human pathogen that causes nosocomial infections. Its prevalence and spread in the environment should not be ignored. This study identified characterized

Language: Английский

Citations

0