Assessing Variability in Children’s Exposure to Contaminants in Food: A Longitudinal Non-Targeted Analysis Study in Miami, Florida

Journal of Xenobiotics, Journal Year: 2025, Volume and Issue: 15(1), P. 11 - 11

Published: Jan. 14, 2025

Food is essential for human survival; however, food can be an important route of exposure to contaminants. This study investigated the presence and distribution anthropogenic contaminants in consumed by families with small children South Florida, United States, evaluating seasonal socio-economic variabilities chemical composition. QuEChERS protocols, followed non-targeted analysis (NTA) using LC-Orbitrap HRMS system, were used comprehensive screening organic The compounds annotated identified Compound Discoverer (CD) software, contaminant distributions analyzed boxplots Principal Component Analysis (PCA). results showed significant differences (p < 0.05). In wet season, a predominance polymers surfactants, such as dodecanedioic acid N-dodecylacrylamide, found food, which might due increased transport industrial pollutants during precipitation, while plasticizers (e.g., bis(2-ethylhexyl) phthalate) drugs warfarin) more prevalent dry could related less dilution effects this period. A higher abundance 1-nitrosopiperidine, present cured meats, was noted from upper classes, lower class benzocaine, common topical anesthetic.

Language: Английский

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Mass and particle size distribution of household dust on children’s hands

Journal of Exposure Science & Environmental Epidemiology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 10, 2025

Abstract Background Children are vulnerable to household dust exposure; however, date, a handful of studies simultaneously report both the mass and particle size found on children’s hands after natural indoor play activities. Objective Evaluate new approach measure loading characterize child’s using Coulter Counter. Methods The volume particles rinsed off was measured through counting sizing (using Counter), followed by multiplying density collected from home. This then normalized per total hand surface area obtain hands. Results were compared region (North Carolina, Florida, Arizona), age groups (6 months 6 years), social demographics (gender, race, ethnicity) for 101 children. estimated median 1.54 g/cm 3 , with an average 1.58 (SD = 0.43). overall 11.13 μg/cm 2 (per area), range 0.004–167.6 . No statistical difference observed region, age, nor (p > 0.05). majority (90%) rinses had diameter (D 90,v ) <35 μm; these small represent fraction mass. succeeded at obtaining loadings same sample, in contrast current methods that would have required multiple sample types. Impact Statement due their behavior; limited measurements available We propose facilitate measurements, while also dust, usage showed 90% μm, which is four times smaller than guidelines threshold (150 μm) risk assessments utilize estimates

Language: Английский

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Per- and Polyfluoroalkyl Ether Acid (PFEA) Concentrations in Indoor Dust are Higher in Homes Closer to a Fluorochemical Manufacturing Facility

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: March 31, 2025

Concentrations of 48 per- and polyfluoroalkyl substances (PFAS) were measured in settled dust samples from 65 homes GenX Exposure Study participants residing near a fluorochemical manufacturing facility North Carolina. Eight PFAS [perfluoro(3,5-dioxahexanoic) acid (aka PFO2HxA), perfluoro-2-(perfluoromethoxy)propanoic (PMPA), perfluoro-2-ethoxypropanoic (PEPA), 6:2 fluorotelomer phosphate diester (6:2 diPAP), 6:2/8:2 (6:2/8:2 perfluoropropanoic (PFPrA), perfluorodecanesulfonic (PFDS), 2-(N-ethyl-perfluorooctanesulfonamido)acetic (N-EtFOSAA)] detected >90% the samples. Dust concentrations six ether acids (PFEAs) produced at (PEPA, PMPA, perfluoro-2-methoxyacetic (PFMOAA), PFO2HxA, hexafluoropropylene oxide dimer (HFPO-DA aka GenX), ethanesulfonic acid, 2-[1-[difluoro(1,2,2,2-tetrafluoroethoxy)methyl]-1,2,2,2- tetrafluoroethoxy]-1,1,2,2-tetrafluoro- (Nafion byproduct 2) significantly negatively associated with home distance facility. Homes closer to had higher summed mass 12 targeted PFEAs (∑12PFEAs) but not ∑48PFAS. Trifluoroacetic (TFA), an ultrashort chain PFAS, three diPAPs (8:2/6:2 diPAP, 8:2 diPAP) major contributors ∑48PFAS, these compounds did show relationships distance. Based on our previous findings associating well water human serum, current indicate could be important exposure source.

Language: Английский

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Non-targeted analysis of odor components and hazardous volatiles in children's raincoats

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 296, P. 118220 - 118220

Published: April 19, 2025

Language: Английский

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