Modified biochar improved simultaneous nitrate removal and soluble microbial products regulation in low carbon wastewater: Insights from the biocarrier and community function

Journal of Water Process Engineering, Journal Year: 2024, Volume and Issue: 65, P. 105762 - 105762

Published: July 17, 2024

Language: Английский

---

Characterization of the Activities of Vorinostat Against Toxoplasma gondii

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(2), P. 795 - 795

Published: Jan. 18, 2025

Toxoplasma gondii is a globally widespread pathogen of significant veterinary and medical importance, causing abortion or congenital disease in humans other warm-blooded animals. Nevertheless, the current treatment options are restricted sometimes result toxic side effects. Hence, it essential to discover drugs that demonstrate potent anti-Toxoplasma activity. Herein, we found vorinostat, pan-HDAC inhibitor, exhibited an IC50 value 260.1 nM against T. RH strain selectivity index (SI) > 800 with respect HFF cells. Vorinostat disrupted entire lytic cycle vitro. Proteome analysis indicated vorinostat remarkably perturbed protein expression gondii, proteins involved “DNA replication” “membrane” were significantly dysregulated. Furthermore, enhanced ROS production induced parasite apoptosis. Importantly, could prolong survival murine model. Our findings reveal effective both vitro vivo, suggesting its potential as therapeutic option for human toxoplasmosis.

Language: Английский

---

Superoxide mediated Mn(II) oxidation of an alkali-tolerant bacterium Pseudorhizobium flavum MXJ-1

Journal of Environmental Sciences, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

---

Draft genome of Pseudomonas sp. XK-1, a marine bacterium capable of degrading lignin and Mn(II) oxidation

Microbiology Resource Announcements, Journal Year: 2024, Volume and Issue: 13(7)

Published: June 12, 2024

ABSTRACT We report the draft genome sequence of marine bacteria, Pseudomonas sp. XK-1. Strain XK-1 could facilitate Mn(II) oxidation with lignin as sole carbon source. The length is 4,751,776 bp, a G + C content 62.61%. Genome analyses reveal and manganese cycling driven by bacteria.

Language: Английский

---

Isolation of halotolerant Pseudomonas sp. KW-2 for the effective degradation p-arsanilic acid and immobilization its released inorganic arsenic

Process Safety and Environmental Protection, Journal Year: 2024, Volume and Issue: 192, P. 1271 - 1282

Published: Nov. 6, 2024

Language: Английский

---