Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 485, P. 136860 - 136860
Published: Dec. 12, 2024
Language: Английский
Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 485, P. 136860 - 136860
Published: Dec. 12, 2024
Language: Английский
Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 487, P. 137196 - 137196
Published: Jan. 13, 2025
Language: Английский
Citations
2Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 5, 2025
The production and weathering processes of nanoparticles (NPs) introduce charged functional groups on their surface. Previous studies have found that the surface charge properties NPs play a critical role in toxic effects mechanisms are generally attributed to different accumulations transmembrane potentials. Currently, we still lack sufficient knowledge about effects, owing unique structures these polymers. In this study, positively (PS-NH2, 50 nm) at 0.05-0.5 μg mL-1 promoted proliferation hepatic tumors oncogenic KrasG12V zebrafish larvae they also increased viability human hepatocellular carcinoma cells, whereas negatively (PS-COOH, did not. We present evidence indicating potential carcinogenicity PS-NH2 is related special polymer-molecular interactions caused by its positive charge. affinity PS-COOH chains for peptides typically enhances enzyme stability upregulates expression. However, strongly competes with hydrogen bonds first rate-limiting PCK1 gluconeogenesis, thus downregulating expression promoting aerobic glycolysis pathway, which most tumor cells prefer. This study indicates positive-charge modified environment may bring additional carcinogenic risks.
Language: Английский
Citations
1Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 29, 2025
Concern over nanoplastic contamination of wetland ecosystems has been increasing. However, little is known about the effect photoaging on distribution and biological response nanoplastics. Here, palladium-labeled polystyrene nanoplastics (PS-Pd NPs) at 0.05-50 mg/L were exposed to constructed microcosms containing floating (Eichhornia crassipes) submerged (Vallisneria natans) macrophytes. Results demonstrate that PS-Pd NPs' concentration in surface water after 2-4 weeks exposure was decreased by 98.4% as compared with 1st week. Photoaging enhanced charge colloidal stability NPs, a subsequent increase content NPs middle layer 264.6 207.4%, respectively. Additionally, significantly accumulation E. crassipes roots 6.9-65.0% it V. natans shoots 59.7-123.0%. inhibited growth 43.8% 50 mg/L. Mechanistically, induced oxidative stress natans, leading disruption metabolic pathway. Interestingly, NP nitrification due alteration related bacterial community (Ellin6067 13.19%). These findings deepen our understanding environmental fate risk plastic particles ecosystems.
Language: Английский
Citations
0Published: Jan. 1, 2025
Language: Английский
Citations
0Published: Jan. 1, 2025
Language: Английский
Citations
0TrAC Trends in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 118270 - 118270
Published: April 1, 2025
Language: Английский
Citations
0Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 493, P. 138369 - 138369
Published: April 22, 2025
Language: Английский
Citations
0The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 953, P. 176223 - 176223
Published: Sept. 11, 2024
Language: Английский
Citations
1Pesticide Biochemistry and Physiology, Journal Year: 2024, Volume and Issue: 206, P. 106202 - 106202
Published: Nov. 2, 2024
Language: Английский
Citations
1Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 485, P. 136860 - 136860
Published: Dec. 12, 2024
Language: Английский
Citations
1