Effect of glucose selenol on hepatic lipid metabolism disorder induced by heavy metal cadmium in male rats DOI

Xinyi Yang,

Jinzhou Huang, Juan Wang

et al.

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Journal Year: 2024, Volume and Issue: unknown, P. 159589 - 159589

Published: Dec. 1, 2024

Language: Английский

Synergistic Effects of Copper and Bile Acids on Cholesterol Reduction in Eggs of Laying Hens DOI Creative Commons
Han Chen, Yifan Li,

Shoukang Cao

et al.

Poultry Science, Journal Year: 2025, Volume and Issue: unknown, P. 105202 - 105202

Published: April 1, 2025

Language: Английский

Citations

0

Pro-Apoptotic and Mitochondria-Disrupting Effects of 4-methylthiazole in K562 Leukemia Cells: A Mechanistic Investigation DOI
Neslihan Meriç,

Ezgi Kar,

Fatih Kar

et al.

Tissue and Cell, Journal Year: 2025, Volume and Issue: 95, P. 102937 - 102937

Published: April 27, 2025

Language: Английский

Citations

0

Lycopene prevents the intestinal toxicity caused by cyclophosphamide via NCOA4-induced ferroptosis pathway DOI
Xiaoran Liu, Yun Dai,

Yupei Yao

et al.

Journal of Functional Foods, Journal Year: 2025, Volume and Issue: 129, P. 106862 - 106862

Published: April 28, 2025

Language: Английский

Citations

0

1α,25-hydroxyvitamin D3 alleviated rotavirus infection induced ferroptosis in IPEC-J2 cells by regulating the ATF3-SLC7A11-GPX4 axis DOI
Zhao Ye, Xiaoxiao Zhu,

Qingkuo Lan

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 283, P. 137484 - 137484

Published: Nov. 9, 2024

Language: Английский

Citations

1

A New Insight into the Mechanism of Atrazine-Induced Neurotoxicity: Triggering Neural Stem Cell Senescence by Activating Integrated Stress Response Pathway DOI Creative Commons
Jian Chen, Xueyan Dai, Kanwar Kumar Malhi

et al.

Research, Journal Year: 2024, Volume and Issue: 7

Published: Jan. 1, 2024

Atrazine (AT), a widely utilized chemical herbicide, causes widespread contamination of agricultural water bodies. Recently, exposure to AT has been linked the development age-related neurodegenerative diseases (NDs), suggesting its neurotoxicity potential. As an endocrine disruptor, targets hypothalamus, crucial part neuroendocrine system. However, toxicological mechanism hypothalamus and correlation with ND remain unexplored. Our results indicated that caused significant morphological structural damage leading loss mature intact neurons microglial activation. Furthermore, hypothalamic neural stem cells (HtNSCs) were recruited areas neuronal by AT. Through in vivo vitro experiments, we clarified outcomes AT-induced HtNSC recruitment alongside mature/intact neurons. Mechanistically, induces senescence these HtNSCs activating integrated stress response signaling. This consequently hinders repair damaged inhibiting proliferation differentiation. Overall, our findings underscore pivotal role pathway damage. Additionally, present study offers novel perspectives understand mechanisms provides preliminary evidence linking NDs.

Language: Английский

Citations

1

The integrated effect of Roflumilast and Selenium Nanoparticles on nephrotoxicity generated by Cisplatin through the regulation of the antioxidant and apoptotic pathways DOI
Nashwa Barakat,

E. G. M. Ismail,

Faten Zahran

et al.

Journal of Trace Elements in Medicine and Biology, Journal Year: 2024, Volume and Issue: 86, P. 127555 - 127555

Published: Oct. 18, 2024

Language: Английский

Citations

0

Klotho improves Der p1-induced bronchial epithelial cell damage by inhibiting endoplasmic reticulum stress to regulate mitochondrial function DOI
Chunguang Wang, Zhimei Liu,

Xiaofei Xie

et al.

Tissue and Cell, Journal Year: 2024, Volume and Issue: 93, P. 102646 - 102646

Published: Nov. 30, 2024

Language: Английский

Citations

0

Effect of glucose selenol on hepatic lipid metabolism disorder induced by heavy metal cadmium in male rats DOI

Xinyi Yang,

Jinzhou Huang, Juan Wang

et al.

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Journal Year: 2024, Volume and Issue: unknown, P. 159589 - 159589

Published: Dec. 1, 2024

Language: Английский

Citations

0