Metagenomic analysis deciphers airborne pathogens with enhanced antimicrobial resistance and virulence factors in composting facilities DOI Creative Commons
Mo Chen,

Lijun Xing,

Shanshan Gao

et al.

Environment International, Journal Year: 2025, Volume and Issue: 201, P. 109569 - 109569

Published: May 30, 2025

The composting process has been shown to effectively reduce antimicrobial resistance (AMR) in animal manure, but its influence on surrounding airborne AMR remains unknown, particularly with regard human-pathogenic antibiotic-resistant bacteria (HPARB). In this study, air and paired compost samples were collected from a full-scale facility, the antibiotic resistome, microbiome, HPARB systematically analyzed both two habitats using metagenomic analysis. Current result uncovered profiles of air, showing that significantly more assembled than samples. Airborne pathogens harboredan increased abundance diversity genes (ARGs) virulence factor (VFGs) comparison compost-borne HPARB. core resistome represents 18.58% overall ARG subtypes, contributing 86.31% abundance. A higher number enriched ARGs (2.16- 13.36-times higher), including mexF, tetW, vanS, observed compared As an important human pathogen, Mycobacterium tuberculosis was prevalent carried (6) VFG (130) subtypes those compost. risk score detected for facility hospital urban environments. This study revealed enhanced through comparative experiments between habitats. It highlighted unrecognized risks associated site provided scientific basis accurately assessing health outcomes caused by occupational exposure.

Language: Английский

Antibiotic Resistance Genes in Aquatic Systems: Sources, Transmission, and Risks DOI
Tingting Zhang,

Linyi Fan,

Yanan Zhang

et al.

Aquatic Toxicology, Journal Year: 2025, Volume and Issue: 284, P. 107392 - 107392

Published: April 29, 2025

Language: Английский

Citations

0
Metagenomic analysis deciphers airborne pathogens with enhanced antimicrobial resistance and virulence factors in composting facilities DOI Creative Commons
Mo Chen,

Lijun Xing,

Shanshan Gao

et al.

Environment International, Journal Year: 2025, Volume and Issue: 201, P. 109569 - 109569

Published: May 30, 2025

The composting process has been shown to effectively reduce antimicrobial resistance (AMR) in animal manure, but its influence on surrounding airborne AMR remains unknown, particularly with regard human-pathogenic antibiotic-resistant bacteria (HPARB). In this study, air and paired compost samples were collected from a full-scale facility, the antibiotic resistome, microbiome, HPARB systematically analyzed both two habitats using metagenomic analysis. Current result uncovered profiles of air, showing that significantly more assembled than samples. Airborne pathogens harboredan increased abundance diversity genes (ARGs) virulence factor (VFGs) comparison compost-borne HPARB. core resistome represents 18.58% overall ARG subtypes, contributing 86.31% abundance. A higher number enriched ARGs (2.16- 13.36-times higher), including mexF, tetW, vanS, observed compared As an important human pathogen, Mycobacterium tuberculosis was prevalent carried (6) VFG (130) subtypes those compost. risk score detected for facility hospital urban environments. This study revealed enhanced through comparative experiments between habitats. It highlighted unrecognized risks associated site provided scientific basis accurately assessing health outcomes caused by occupational exposure.

Language: Английский

Citations

0