Water,
Journal Year:
2025,
Volume and Issue:
17(4), P. 468 - 468
Published: Feb. 7, 2025
Sulfamethazine
(SM2),
a
prevalent
sulfonamide
antibiotic,
is
commonly
detected
as
an
environmental
pollutant.
Microbial
degradation
serves
important
approach
to
treating
SM2
contamination.
In
this
study,
SM2-degrading
strain,
identified
Bacillus
cereus
J2,
was
isolated
from
the
activated
sludge
that
had
been
cultured
using
exclusive
carbon
source,
which
demonstrated
exceptional
capabilities.
Under
optimized
conditions
(30
°C,
initial
OD600
=
0.1,
pH
8),
strain
J2
completely
degraded
50
mg/L
within
36
h.
The
also
showed
high
efficiency
for
other
sulfonamides,
such
sulfamethoxazole
and
sulfadiazine,
could
grow
normally
in
mixed
system
containing
these
compounds.
growth
kinetics
with
source
conformed
well
Haldane
model
(R2
0.925),
revealing
strain’s
maximum
specific
rate
determined
be
0.066
h−1
(µmax)
at
concentration
of
51.35
mg/L.
Seven
intermediate
products
were
TQ-LCMS
analysis,
suggesting
three
potential
pathways
SM2.
These
findings
suggest
holds
significant
promise
bioremediation
SM2-contaminated
environments.
