Longitudinal Trends and Drivers of Antimicrobial Resistance in Campylobacter Worldwide (1954-2023) DOI Creative Commons
Shulei Jia, Xuebin Xu, Mengqi Qu

et al.

Zoonoses, Journal Year: 2025, Volume and Issue: 5(1)

Published: Jan. 1, 2025

Objective: The zoonotic pathogen Campylobacter is a major foodborne bacterial species worldwide. distribution and drivers of antimicrobial resistance (AMR) in global strains remain largely unknown. Therefore, comprehensive analysis longitudinal trends driving factors AMR necessary at level. Methods: We downloaded from public repositories 66,771 genomes (24,115 C. coli 42,656 jejuni ) 53 countries/regions during 1954–2023, performed analysis. Results: categorized the isolates into 2,771 sequence types (STs), 45 which were shared among humans, chickens, pigs, cattle, environment. uncovered spatial temporal characteristics across classes on scale, observed increased aminoglycoside, tetracycline, fluoroquinolone past 23 years. Some antibiotic, climate, socioeconomic indicators collected World Bank might potentially have driven rise various to varying degrees. Conclusions: In summary, we present genetic atlas , provides valuable insights for understanding transmission dynamics this species.

Language: Английский

Longitudinal Trends and Drivers of Antimicrobial Resistance in Campylobacter Worldwide (1954-2023) DOI Creative Commons
Shulei Jia, Xuebin Xu, Mengqi Qu

et al.

Zoonoses, Journal Year: 2025, Volume and Issue: 5(1)

Published: Jan. 1, 2025

Objective: The zoonotic pathogen Campylobacter is a major foodborne bacterial species worldwide. distribution and drivers of antimicrobial resistance (AMR) in global strains remain largely unknown. Therefore, comprehensive analysis longitudinal trends driving factors AMR necessary at level. Methods: We downloaded from public repositories 66,771 genomes (24,115 C. coli 42,656 jejuni ) 53 countries/regions during 1954–2023, performed analysis. Results: categorized the isolates into 2,771 sequence types (STs), 45 which were shared among humans, chickens, pigs, cattle, environment. uncovered spatial temporal characteristics across classes on scale, observed increased aminoglycoside, tetracycline, fluoroquinolone past 23 years. Some antibiotic, climate, socioeconomic indicators collected World Bank might potentially have driven rise various to varying degrees. Conclusions: In summary, we present genetic atlas , provides valuable insights for understanding transmission dynamics this species.

Language: Английский

Citations

0