Journal of Polymers and the Environment, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 30, 2024
Language: Английский
Nature Reviews Bioengineering, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 28, 2025
Language: Английский
Citations
1
Carbohydrate Polymer Technologies and Applications, Journal Year: 2025, Volume and Issue: unknown, P. 100708 - 100708
Published: Feb. 1, 2025
Language: Английский
Citations
1
Polymer Reviews, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 65
Published: Nov. 20, 2024
The biomedical industry has witnessed a transformative evolution with the advent of 3D printing technology. However, inherent limitations, such as inability to produce dynamic human tissues due absence temporal dimension, have persisted, resulting in static and inanimate printed products. To address this challenge enable creation living constructs, concept 4D emerged, marking paradigm shift additive manufacturing. In printing, time becomes fourth breathing life into previously creations. This review paper explores journey from pivotal role manufacturing process. Specifically, it highlights integration time-dependent responsive materials, focusing on stimuli-responsive hydrogels, cornerstone advancements. These materials exhibit remarkable ability adapt respond various stimuli, encompassing physical, chemical, biological signals. delves recent publications synergy between these stimuli shedding light their intricate interactions potential applications. One primary areas interest lies medical applications, notably tissue engineering, where holds immense promise. utilization creating biomimetic scaffolds that can dynamically complex environments. Furthermore, discusses technical considerations prospects technology, emphasizing its revolutionize landscape. amalgamation opens new avenues for personalized medicine, localized drug delivery, regenerative therapies, bridging gap requirements modern healthcare. present offers complete examination evolution, challenges, paving way innovations field.
Language: Английский
Citations
6
Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 12
Published: Jan. 10, 2025
Medical implants are designed to replace missing parts or improve body functions and must be capable of providing structural support therapeutic intervention for a medical condition. Advances in materials science have enabled the development devices made from metals, polymers, bioceramics, composites, each with its specific advantages limitations. This review analyzes incorporation biopolymers, proteins, other biomacromolecules into implants, focusing on their role biological integration functions. It synthesizes advancements surface modification, discusses as carriers controlled drug release, explores application nanoceramics composites osseointegration tissue regeneration. Biomacromolecule systems interacting device components agents - such growth factors (GFs), antibiotics, allowing control over substance release. Incorporating these enables localized treatments regeneration, osseointegration, post-surgery infection control, disease pre-existing conditions. The highlights materials' customization opportunities, by covering mechanical perspectives. Developing hybrid delivery align recent efforts interdisciplinary personalized medicine implant innovations. For instance, trend was observed integrating inorganic (especially nanoceramics, e.g., hydroxyapatite) organic phases better interaction tissues faster recovery. article supports understanding how can create more personalized, functional, durable, biocompatible devices.
Language: Английский
Citations
0
Polymer International, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 29, 2025
Abstract The degradation of polymer‐based materials is crucial for their end‐of‐life management, particularly in biomedical applications where controlled rates are essential. Addressing this need, study explores the incorporation newly designed polyanhydrides (PAs) into multicomponent blends to enhance hydrolytic biodegradation. Two distinct PAs – poly[(propionic anhydride)‐ co ‐(succinic anhydride)] (PASA) and ‐(sebacic (PASEA) were synthesized through melt‐condensation polymerization. These then incorporated solution blend films composed poly( l ‐lactide) (PLLA), ε ‐caprolactone) (PCL) cellulose acetate butyrate (CAB), aiming serve as an accelerator films. PASA PASEA PLLA/PCL/CAB resulted formation phase‐separated domains a notable shift carbonyl frequency band Fourier transform infrared spectra, indicating phase separation intermolecular packing between homopolymers system. Significant changes molecular weight surface morphology with observed after 0, 3 6 months storage. observations confirmed role accelerating erosion, evidenced by presence craze lines at both macrophase‐ microphase‐separated domains. This highlights potential PA additives stability film. Such enhancements valuable designing rates, which important precise timing within body © 2025 Society Chemical Industry.
Language: Английский
Citations
0
Journal of Biomaterials Science Polymer Edition, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 27
Published: Feb. 7, 2025
In orthopaedic clinical applications, creating biocomposite bone substitutes to take the place of autologous transplants is still difficult. Studies have demonstrated for decades that poly (lactic-co-glycolic acid) [PLGA], a common polymer, has many benefits make it strong contender replacement. These include biodegradability, good mechanical qualities, and ability induce new production. Although calcium-based materials are frequently used as fillers in implantation, efficiency ceramic containing calcium may be hampered by number issues, including low microporosity quick rates degradation. order overcome these obstacles, scientists investigating ways improve implant performance combining PLGA with other materials, especially terms encouraging improved connections nearby cells. An overview chemical properties different PLGA-based scaffold composites, well drawbacks PLGA-Calcium implants tissue engineering goals this review. It also highlights possible advantages consequences using 3D printing technology outcomes.
Language: Английский
Citations
0
Polymer, Journal Year: 2025, Volume and Issue: unknown, P. 128168 - 128168
Published: Feb. 1, 2025
Language: Английский
Citations
0
ACS Biomaterials Science & Engineering, Journal Year: 2025, Volume and Issue: unknown
Published: March 11, 2025
Roughly 1.71 billion people worldwide suffer from large bone abnormalities, which are the primary cause of disability. Traditional grafting procedures have several drawbacks that impair their therapeutic efficacy and restrict use in clinical settings. A great deal work has been done to create fresh, more potent strategies. Under these circumstances, a crucial technique for regeneration major lesions emerged: tissue engineering (BTE). BTE involves biomaterials can imitate natural design bone. To yet, no biological material able fully meet parameters perfect implantable material, even though varieties created investigated regeneration. Against this backdrop, researchers focused interest over past few years on subject nanotechnology nanostructures regenerative medicine. The ability nanoengineered particles overcome current constraints strategies─such as decreased cell proliferation differentiation, insufficient mechanical strength materials, production extrinsic factors required effective osteogenesis revolutionized field engineering. effects nanoparticles characteristics application materials main topics our review, summarizes most recent vitro vivo research context BTE.
Language: Английский
Citations
0
Journal of Industrial and Engineering Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: March 1, 2025
Language: Английский
Citations
0
Bioactive Materials, Journal Year: 2025, Volume and Issue: 50, P. 189 - 214
Published: April 10, 2025
Language: Английский
Citations
0