The Impact of the COVID-19 Pandemic on the Antibiotic Resistance of Gram-Negative Pathogens Causing Bloodstream Infections in an Intensive Care Unit DOI Creative Commons
Andreea Loredana Golli, Simona Georgiana Popa, Alice Elena Ghenea

et al.

Biomedicines, Journal Year: 2025, Volume and Issue: 13(2), P. 379 - 379

Published: Feb. 6, 2025

Background/Objectives: In this research, we aimed to analyze the trend of antimicrobial resistance pattern Gram-negative isolated in blood samples collected from patients with severe invasive infections hospitalized intensive care unit selected periods during and after COVID-19. Methods: A retrospective study bacterial pathogens was performed on 481 admitted ICU between 2020 2023. The patterns were analyzed using Vitek 2 Compact system. Results. total 686 isolates obtained. most frequently detected Klebsiella spp. (30.91%), Acinetobacter (24.64%), Escherichia coli (18.95%). Almost 50% all multidrug-resistant, a statistically significant increase post-pandemic (p < 0.05). Post-pandemic, highlighted significantly higher percentage strains 0.05), antibiotic rate against colistin 0.001) tigecycline = 0.005). very high MDR found, 0.001). lower recorded for case ceftazidime 0.03) aminoglycosides (gentamicin—p 0.01, amikacin—p An carbapenem-resistant spp., Enterobacter observed, decrease Proteus 0.01). Conclusions: Our findings revealed last-line antibiotics post-COVID-19 era.

Language: Английский

The Impact of the COVID-19 Pandemic on the Antibiotic Resistance of Gram-Negative Pathogens Causing Bloodstream Infections in an Intensive Care Unit DOI Creative Commons
Andreea Loredana Golli, Simona Georgiana Popa, Alice Elena Ghenea

et al.

Biomedicines, Journal Year: 2025, Volume and Issue: 13(2), P. 379 - 379

Published: Feb. 6, 2025

Background/Objectives: In this research, we aimed to analyze the trend of antimicrobial resistance pattern Gram-negative isolated in blood samples collected from patients with severe invasive infections hospitalized intensive care unit selected periods during and after COVID-19. Methods: A retrospective study bacterial pathogens was performed on 481 admitted ICU between 2020 2023. The patterns were analyzed using Vitek 2 Compact system. Results. total 686 isolates obtained. most frequently detected Klebsiella spp. (30.91%), Acinetobacter (24.64%), Escherichia coli (18.95%). Almost 50% all multidrug-resistant, a statistically significant increase post-pandemic (p < 0.05). Post-pandemic, highlighted significantly higher percentage strains 0.05), antibiotic rate against colistin 0.001) tigecycline = 0.005). very high MDR found, 0.001). lower recorded for case ceftazidime 0.03) aminoglycosides (gentamicin—p 0.01, amikacin—p An carbapenem-resistant spp., Enterobacter observed, decrease Proteus 0.01). Conclusions: Our findings revealed last-line antibiotics post-COVID-19 era.

Language: Английский

Citations

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