One Health Bulletin,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 23, 2024
Antimicrobial
resistance
(AMR)
has
become
a
serious
threat
to
global
public
health.
By
2050,
AMR
is
estimated
cause
1.91
million
deaths
annually,
with
related
mortality
reaching
8.22
million.
The
challenges
posed
by
extend
beyond
the
healthcare
system
include
animal
health
and
environmental
factors
such
as
livestock
farming,
urbanization,
climate
change.
“One
Health”
approach,
an
interdisciplinary
cross-regional
collaborative
strategy,
integrates
management
of
human,
animal,
It
considered
crucial
framework
for
addressing
complex
providing
both
scientific
preventive
strategies
combat
AMR.
From
October
12
13,
2024,
Second
One
Health
Conference
Resistance
Containment
was
successfully
held
in
Hangzhou,
Zhejiang
Province,
China,
under
theme
“Hand
Hand
Contain
AMR”.
conference
brought
together
experts
from
various
fields
engage
in-depth
discussions
on
control,
consensus
take
action
towards
advancing
community.
This
strengthened
multi-sectoral
collaboration,
promoted
cross-departmental
cross-national
cooperation,
enhanced
awareness
AMR,
explored
control
mechanisms,
provided
theoretical
practical
guidance
mitigating
also
called
increased
investment
research
development
efforts
containment.
Biomimetics,
Journal Year:
2024,
Volume and Issue:
9(7), P. 425 - 425
Published: July 12, 2024
In
light
of
rising
public
health
threats
like
antifungal
and
antimicrobial
resistance,
alongside
the
slowdown
in
new
development,
biomimetics
have
shown
promise
as
therapeutic
agents.
Multidrug-resistant
fungi
pose
significant
challenges
they
quickly
develop
making
traditional
antifungals
less
effective.
Developing
is
also
complicated
by
need
to
target
eukaryotic
cells
without
harming
host.
This
review
examines
biomimetic
materials
that
mimic
natural
biological
mechanisms
for
targeted
efficient
action.
It
covers
a
range
agents,
including
peptides,
alginate-based
antifungals,
chitosan
derivatives,
nanoparticles,
plant-derived
polyphenols,
probiotic
bacteria.
These
agents
work
through
such
disrupting
cell
membranes,
generating
reactive
oxygen
species,
inhibiting
essential
fungal
processes.
Despite
their
potential,
remain
terms
ensuring
biocompatibility,
optimizing
delivery,
overcoming
potential
resistance.
Production
scalability
economic
viability
are
concerns.
Future
research
should
enhance
stability
efficacy
these
materials,
integrate
multifunctional
approaches,
sophisticated
delivery
systems.
Interdisciplinary
efforts
needed
understand
interactions
between
cells,
host
environment.
Long-term
environmental
impacts,
resistance
mechanisms,
standardized
testing
protocols
require
further
study.
conclusion,
while
represent
revolutionary
approach
combating
multidrug-resistant
fungi,
extensive
development
fully
realize
potential.
One Health Bulletin,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 23, 2024
Antimicrobial
resistance
(AMR)
has
become
a
serious
threat
to
global
public
health.
By
2050,
AMR
is
estimated
cause
1.91
million
deaths
annually,
with
related
mortality
reaching
8.22
million.
The
challenges
posed
by
extend
beyond
the
healthcare
system
include
animal
health
and
environmental
factors
such
as
livestock
farming,
urbanization,
climate
change.
“One
Health”
approach,
an
interdisciplinary
cross-regional
collaborative
strategy,
integrates
management
of
human,
animal,
It
considered
crucial
framework
for
addressing
complex
providing
both
scientific
preventive
strategies
combat
AMR.
From
October
12
13,
2024,
Second
One
Health
Conference
Resistance
Containment
was
successfully
held
in
Hangzhou,
Zhejiang
Province,
China,
under
theme
“Hand
Hand
Contain
AMR”.
conference
brought
together
experts
from
various
fields
engage
in-depth
discussions
on
control,
consensus
take
action
towards
advancing
community.
This
strengthened
multi-sectoral
collaboration,
promoted
cross-departmental
cross-national
cooperation,
enhanced
awareness
AMR,
explored
control
mechanisms,
provided
theoretical
practical
guidance
mitigating
also
called
increased
investment
research
development
efforts
containment.
