Comparative analysis of croup severity and treatment in pediatric patient: a study of COVID-19 positive vs. negative cases during peak Omicron DOI Creative Commons
Fatemeh Pourjoula, Seyed Hossein Mirlohi, Niloofar Ghanbari

et al.

BMC Pediatrics, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 15, 2025

The Omicron variant of SARS-CoV-2 has been associated with unique clinical presentations in children, including croup-like symptoms such as barking cough, hoarseness, and respiratory distress. This study aimed to compare the clinical, laboratory, treatment characteristics hospitalized pediatric patients croup who tested positive or negative for COVID-19 during wave. A retrospective, descriptive-analytical was conducted on 111 at Bahrami Children's Hospital Medical Center Iran from January 21 March 20, 2022. Patients were categorized into two groups: PCR-positive (Omicron group, n = 30) PCR-negative (non-Omicron 81). Data demographics, severity, laboratory indices, treatments, outcomes extracted analyzed using SPSS version 20. mean age group significantly younger (16.93 ± 24.80 months) compared non-Omicron (32.58 37.26 months; p 0.049). Symptom severity higher moderate severe observed 73.4% patients, 32.1% (p 0.001). had longer hospital stays (2.59 3.93 vs. 2.11 2.75 days; 0.016) required more nebulized epinephrine (2.47 1.27 1.77 1.003 0.003) repeat corticosteroid doses (83.3% 38.3%; 0.0001). Laboratory findings showed no significant differences between groups (all > 0.05). Children surge exhibited increased symptom intensive treatment, experienced those without COVID-19. These emphasize need heightened awareness tailored management strategies Omicron-related populations.

Language: Английский

Comparative analysis of croup severity and treatment in pediatric patient: a study of COVID-19 positive vs. negative cases during peak Omicron DOI Creative Commons
Fatemeh Pourjoula, Seyed Hossein Mirlohi, Niloofar Ghanbari

et al.

BMC Pediatrics, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 15, 2025

The Omicron variant of SARS-CoV-2 has been associated with unique clinical presentations in children, including croup-like symptoms such as barking cough, hoarseness, and respiratory distress. This study aimed to compare the clinical, laboratory, treatment characteristics hospitalized pediatric patients croup who tested positive or negative for COVID-19 during wave. A retrospective, descriptive-analytical was conducted on 111 at Bahrami Children's Hospital Medical Center Iran from January 21 March 20, 2022. Patients were categorized into two groups: PCR-positive (Omicron group, n = 30) PCR-negative (non-Omicron 81). Data demographics, severity, laboratory indices, treatments, outcomes extracted analyzed using SPSS version 20. mean age group significantly younger (16.93 ± 24.80 months) compared non-Omicron (32.58 37.26 months; p 0.049). Symptom severity higher moderate severe observed 73.4% patients, 32.1% (p 0.001). had longer hospital stays (2.59 3.93 vs. 2.11 2.75 days; 0.016) required more nebulized epinephrine (2.47 1.27 1.77 1.003 0.003) repeat corticosteroid doses (83.3% 38.3%; 0.0001). Laboratory findings showed no significant differences between groups (all > 0.05). Children surge exhibited increased symptom intensive treatment, experienced those without COVID-19. These emphasize need heightened awareness tailored management strategies Omicron-related populations.

Language: Английский

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