A graphene oxide/polyaniline nanocomposite biosensor: synthesis, characterization, and electrochemical detection of bilirubin

RSC Advances, Journal Year: 2023, Volume and Issue: 13(51), P. 36280 - 36292

Published: Jan. 1, 2023

The level of free bilirubin is a considerable index for the characterization jaundice-related diseases. Herein, biosensor was fabricated via immobilization oxidase (BOx) on graphene oxide (GO) and polyaniline (PANI) that were electrochemically co-precipitated indium tin (ITO) conductive glass. structural enzyme electrode characterized by FTIR, XRD, Raman spectroscopy, while spectral thermal properties investigated UV-vis thermogravimetric analysis (TGA). Owing to activity BOx/GO@PANI/ITO biosensor, it could detect with good selectivity sensitivity in low response time. electrochemical studied using impedance spectroscopy (EIS) cyclic voltammetry (CV). At polarization potential 0.2 V vs. Ag/AgCl, sensor illustrated only 2 s at 30 °C pH 7.5. LOD LOQ calculated found be 0.15 nM 2.8 nM, respectively. signal showed linear concentration range 0.01-250 μM. 5 °C, demonstrated half-time 120 days, through which utilized 100 times this temperature conditions. By common colorimetric method, data levels serum determination coefficient (R2) 0.97.

Language: Английский

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Severe plastic deformation: Nanostructured materials, metal-based and polymer-based nanocomposites: A review

Heliyon, Journal Year: 2023, Volume and Issue: 9(12), P. e22559 - e22559

Published: Nov. 23, 2023

Significant deformation of the metal structure can be achieved without breaking or cracking metal. There are several methods for plastics. The most important these angular channel pressing process, high-pressure torsion, multidirectional forging extrusion-cyclic compression cumulative climbing connection consecutive concreting and smoothing method, pipe torsion. nanocomposite is a multiphase material which size one its phases less than 100 nm in at least dimension. Due to some unique properties, metal-based nanocomposites widely used engineering applications such as automotive aerospace industries. Polymer-based two-phase systems with polymer-based reinforcing (usually ceramic). These materials have simpler synthesis process variety industry, gas pipelines, sensors. Severe plastic (SPD) known best method producing bulk ultrafine grained nanostructured excellent properties. Different were developed that suitable sheet solid materials. During past decade, efforts been made create effective processes cylindrical tubes. In this paper, we review intended tubes, their effects on properties severe briefly introduced common materials, sheets, pipes, well background nanocomposites, concisely microstructural mechanical discussed. paper will focus introduction tube processes, then comparison them based advantages disadvantages from viewpoints processing

Language: Английский

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Application of Carbon Nanotubes and Graphene-Based Nanoadsorbents in Water Treatment

BioNanoScience, Journal Year: 2023, Volume and Issue: 13(4), P. 1418 - 1436

Published: Aug. 19, 2023

Language: Английский

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Nanomaterials as transmitters of non-viral gene vectors: A review

Case Studies in Chemical and Environmental Engineering, Journal Year: 2023, Volume and Issue: 8, P. 100372 - 100372

Published: May 8, 2023

With the rapid development of nanotechnology in recent decade, novel DNA and RNA delivery systems for gene therapy have become available that can be used instead viral vectors. These non-viral vectors made a variety materials, including inorganic nanoparticles, carbon nanotubes, liposomes, protein peptide-based as well nanoscale polymeric materials. They advantages over decreased immune response, additionally offer flexibility design, allowing them to functionalized targeted specific sites biological system with low cytotoxicity.gene keeps hopes life treatment wide range diseases such cancer, nano particles are now known promising carriers effective safe genes cells or tissues. This could provide alternative therapies conventional approaches use viruses carriers. The expression genetic material DNA, into tissues has raised considerable therapeutic diagnostic purposes. But getting nucleic acids cell also faces challenges. challenges less non-virus drug method than free therefore considered risky more appropriate. expanding nonverbal carriers, we will look at few these penicillin, PEI, PLGA, silica, block copolymer, Quantum dot, gold particles, common tubes. Problems include polymer solid lipid investigated. Gene-based is intentional modulation treat pathological conditions. accomplished by introducing exogenous mRNA, small interfering (siRNA), microRNA (miRNA) antisense oligonucleotides. Given large size negative charge macromolecules, their typically mediated In this Review, introduce barriers vivo discuss advances sciences, acid chemistry yielded systems, some which currently undergoing testing clinical trials. diversity highlights progress gene-based using approaches.

Language: Английский

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Properties and Application of Nanostructure in Liquid Crystals: Review

BioNanoScience, Journal Year: 2023, Volume and Issue: 13(2), P. 819 - 839

Published: March 24, 2023

Language: Английский

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