[Erratum] Brain Imaging and neurostimulation in health and disorders: status report DOI Creative Commons
Abrahão Fontes Baptista, Adenauer G. Casali, Adriana Leico Oda

et al.

Brain Imaging and Stimulation, Journal Year: 2024, Volume and Issue: 3, P. e5952 - e5952

Published: Oct. 15, 2024

INTRODUCTION: Despite being considered least important for clinical practice in the pyramid of evidence recommendations, sometimes scientists' expert opinions could help to better understand summarization updated publications. OBJECTIVE: To provide a major summarized update about brain imaging and stimulation nervous system health disease. METHODS: Comprehensive review developed by experts each subarea knowledge neuroimaging non-invasive system. A team researchers clinic was invited present an on their area expertise. RESULTS: In basics techniques, we approach general quantitative electroencephalography, functional magnetic resonance imaging, near-infrared spectroscopy, experimental paradigms studies. Were included associations between transcranial electromyography, evaluate activity. Furthermore, showed several actualized central peripheral neuromodulation techniques. And finally, presented different performance uses neuromodulation. CONCLUSION: our knowledge, this is concentrated that can benefit neuroscience clinicians from levels experience.

Language: Английский

Natural Oscillatory Frequency Slowing in the Premotor Cortex of Early-Course Schizophrenia Patients: A TMS-EEG Study DOI Creative Commons
Francesco Donati, Ahmad Mayeli,

Kamakashi Sharma

et al.

Brain Sciences, Journal Year: 2023, Volume and Issue: 13(4), P. 534 - 534

Published: March 24, 2023

Despite the heavy burden of schizophrenia, research on biomarkers associated with its early course is still ongoing. Single-pulse Transcranial Magnetic Stimulation coupled electroencephalography (TMS-EEG) has revealed that main oscillatory frequency (or "natural frequency") reduced in several frontal brain areas, including premotor cortex, chronic patients schizophrenia. However, no study explored natural at beginning illness. Here, we used TMS-EEG to probe intrinsic properties left cortex early-course schizophrenia (<2 years from onset) and age/gender-matched healthy comparison subjects (HCs). State-of-the-art real-time monitoring EEG responses TMS noise-masking procedures were employed ensure data quality. We found was significantly compared HCs. No correlation between age, clinical symptom severity, or dose antipsychotic medications time TMS-EEG. This finding extends previous evidence supports hypothesis a deficit cortical synchronization as core mechanism underlying this disorder. Future work should further explore putative role frequencies pathophysiological for

Language: Английский

Citations

8
Towards the definition of a standard in TMS-EEG data preprocessing DOI Creative Commons
Adriana Brancaccio, Davide Tabarelli, Agnese Zazio

et al.

NeuroImage, Journal Year: 2024, Volume and Issue: unknown, P. 120874 - 120874

Published: Sept. 1, 2024

Language: Английский

Citations

3
After 55 Years of Neurorehabilitation, What Is the Plan? DOI Creative Commons
Hélène Viruega, Manuel Gaviria

Brain Sciences, Journal Year: 2022, Volume and Issue: 12(8), P. 982 - 982

Published: July 26, 2022

Neurological disorders often cause severe long-term disabilities with substantial activity limitations and participation restrictions such as community integration, family functioning, employment, social interaction participation. Increasing understanding of brain functioning has opened new perspectives for more integrative interventions, boosting the intrinsic central nervous system neuroplastic capabilities in order to achieve efficient behavioral restitution. Neurorehabilitation must take into account many aspects individual through a comprehensive analysis actual potential cognitive, behavioral, emotional physical skills, while increasing awareness self person being dealt with. The exclusive adoption by rehabilitator objective functional measures overlooks values goals disabled person. Indeed, each their own rhythm, unique life history personality construct. In this challenging context, it is essential deepen assessment subjective measures, which adequately reflect patient’s perspective shape genuinely tailored instead standardized neurorehabilitation approaches. overly complex panorama, where confounding prognostic factors also strongly influence recovery, healthcare needs rethink formats.

Language: Английский

Citations

12
Classical, spaced, or accelerated transcranial magnetic stimulation of motor cortex for treating neuropathic pain: A 3-arm parallel non-inferiority study DOI
Thibaut Mussigmann, Benjamin Bardel, Silvia Casarotto

et al.

Neurophysiologie Clinique, Journal Year: 2024, Volume and Issue: 54(6), P. 103012 - 103012

Published: Sept. 14, 2024

Language: Английский

Citations

1
Transcranial Magnetic Stimulation DOI
Luigi Cattaneo

Neuromethods, Journal Year: 2024, Volume and Issue: unknown, P. 461 - 508

Published: Dec. 11, 2024

Citations

1
Phase-dependent stimulation response is shaped by the brain’s transient collective dynamics DOI Creative Commons
Sophie Benitez Stulz, Boris Gutkin, Matthieu Gilson

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: May 9, 2023

Abstract Exogenous stimulation is a promising tool for investigating and altering cognitive processes in the brain, with potential clinical applications. Following experimental observations, we hypothesise that effect of crucially depends on endogenous dynamics brain. Our study explores how local global dynamical properties, like phase regional oscillatory activity transient network states, modulate single pulse large-scale network. findings demonstrate strongly interplay between stimulated phase, state, brain region. Importantly, show not only state-dependent but can also induce state switching. Lastly, predicting by using machine learning shows state-aware measures increase performance up to 40%. results suggest fine characterisation complex setups essential improving reliability exogenous stimulation.

Language: Английский

Citations

3
Motor Cortical Correlates of Paired Associative Stimulation Induced Plasticity: A TMS-EEG Study DOI Creative Commons
Matteo Costanzo, Giorgio Leodori,

Carolina Cutrona

et al.

Brain Sciences, Journal Year: 2023, Volume and Issue: 13(6), P. 921 - 921

Published: June 7, 2023

Paired associative stimulation (PAS) is a non-invasive brain technique that modulates synaptic plasticity in the human motor cortex (M1). Since previous studies have primarily used motor-evoked potentials (MEPs) as outcome measure, cortical correlates of PAS-induced remain unknown. Therefore, aim this observational study was to investigate standard PAS induced primary by using combined TMS-EEG approach cohort eighteen healthy subjects. In addition expected long-lasting facilitatory modulation MEPs amplitude, intervention also significant increase transcranial magnetic stimulation-evoked (TEPs) P30 and P60 amplitude. No correlation between magnitude changes TEP components MEP amplitude were observed. However, linear regression analysis revealed component amplitudes significantly predicted facilitation after PAS. The findings our offer novel insight into neurophysiological associated with at M1 level suggest complex relationship TEPs following

Language: Английский

Citations

3
Brain oscillatory modes as a proxy of stroke recovery DOI Open Access
Sylvain Harquel, Friedhelm C. Hummel

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Feb. 4, 2023

Background: Stroke is the leading cause of long-term disability, making search for successful rehabilitation treatment one most important public health issues. A better understanding neural mechanisms underlying impairment and recovery, development associated biomarkers critical tailoring treatments with ultimate goal maximizing therapeutic outcomes. Here, we studied longitudinal changes in brain oscillatory modes, linked to GABAergic system activity, determined their importance residual upper-limb motor functions recovery. Methods: Transcranial Magnetic Stimulation (TMS) was combined multichannel Electroencephalography (EEG) analyze TMS-induced oscillations a cohort 66 stroke patients from acute late subacute phase after stroke. Results: data-driven parallel factor analysis (PARAFAC) approach tensor decomposition allowed detect modes notably driven by α frequency band, which evolved longitudinally across stages. Notably, observed modulations α-mode, known be were extent Conclusions: Overall, evaluation provides novel insights into functional reorganization networks its mechanisms. propose that α-mode decrease corresponds beneficial disinhibition between early stages fosters structural plasticity facilitates Monitoring this phenomenon at individual patient level will provide information phenotyping patients, developing electrophysiological refining therapies based on personalized excitatory/inhibitory neuromodulation using noninvasive or invasive stimulation techniques.

Language: Английский

Citations

2
Fronto-central resting-state 15-29Hz transient beta events change with therapeutic transcranial magnetic stimulation for posttraumatic stress disorder and major depressive disorder DOI Open Access

Alexander Morris,

Simona Temereanca, Amin Zandvakili

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: March 16, 2023

ABSTRACT Repetitive transcranial magnetic stimulation (rTMS) is an established treatment for major depressive disorder (MDD) and shows promise posttraumatic stress (PTSD), yet effectiveness varies. Electroencephalography (EEG) can identify rTMS-associated brain changes. EEG oscillations are often examined using averaging approaches that mask finer time-scale dynamics. Recent advances show some emerge as transient increases in power, a phenomenon termed “Spectral Events,” event characteristics correspond with cognitive functions. We applied Spectral Event analyses to potential biomarkers of effective rTMS treatment. Resting 8-electrode was collected from 23 patients MDD PTSD before after 5Hz targeting the left dorsolateral prefrontal cortex. Using open-source toolbox ( https://github.com/jonescompneurolab/SpectralEvents ), we quantified features tested associated Events delta/theta (1-6 Hz), alpha (7-14 beta (15-29 Hz) bands occurred all patients. rTMS-induced improvement comorbid were pre-to post-treatment changes fronto-central electrode features, including frontal frequency spans durations, central maxima power. Furthermore, pre-treatment duration correlated negatively symptom improvement. Beta events may provide new clinical response advance understanding rTMS.

Language: Английский

Citations

1
Monitoring Changes in TMS-Evoked EEG and EMG Activity During 1 Hz rTMS of the Healthy Motor Cortex DOI Creative Commons
Stefan Schoisswohl, Carolina Kanig, Mirja Osnabruegge

et al.

eNeuro, Journal Year: 2024, Volume and Issue: 11(4), P. ENEURO.0309 - 23.2024

Published: April 1, 2024

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain technique capable of inducing neuroplasticity as measured by changes in peripheral muscle electromyography (EMG) or electroencephalography (EEG) from pre-to-post stimulation. However, temporal courses neuromodulation during ongoing rTMS are unclear. Monitoring cortical dynamics via TMS-evoked responses using EMG (motor-evoked potentials; MEPs) and EEG (transcranial-evoked TEPs) might provide further essential insights into its mode action – course potential modulations. The objective this study was to first evaluate the validity online rTMS-EEG rTMS-EMG analyses, second scrutinize TEPs MEPs rTMS. As subject high inter-individual effect variability, we aimed for single-subject analyses Ten healthy human participants were stimulated with 1,000 pulses 1 Hz over motor cortex, while recorded continuously. Validity assessed sensor source space. Electrophysiological evaluated model fitting approaches on group- level. appearance consistent past findings single pulse experiments. Heterogeneous progressions, fluctuations saturation effects activity observed depending TEP component. Overall, global increased Single-subject analysis revealed activity. present favor dose-response considerations attempts personalization protocols.

Language: Английский

Citations

0