Prevalence of metabolic syndrome in patients with inflammatory bowel disease: a meta-analysis on a global scale DOI Creative Commons
Krishnamachari Janani, Parsa Saberian,

Hardik Patel

et al.

Journal of Health Population and Nutrition, Journal Year: 2025, Volume and Issue: 44(1)

Published: April 9, 2025

Metabolic syndrome (MetS) is a cluster of metabolic abnormalities that increase the risk cardiovascular diseases (CVD). Patients with inflammatory bowel disease (IBD) may be at higher developing MetS due to chronic inflammation, altered adipokine profiles, and effects corticosteroid treatment. However, prevalence in IBD patients remains inconsistent across studies. This meta-analysis aims estimate compare its occurrence between Crohn's (CD) ulcerative colitis (UC). A systematic search was conducted PubMed, Scopus, Embase, Web Science from their inception up January 19, 2025. Eligible observational studies reporting were included. Meta-analysis performed using random-effects model, heterogeneity assessed via I² statistic. Comprehensive Meta-Analysis (CMA) software, version 4.0 used for analysis. The pooled 21.8% (95% CI: 14.3-31.6%). UC (32.7%, 95% 16.0-55.5%) compared CD (14.1%, 8.6-22.3%). had significantly odds than those (OR = 1.38, 1.03-1.85, P 0.02). Additionally, older without (MD: 9.89, 5.12-14.67, < 0.01). In summary, this reveals notable among IBD, particularly UC, where CD. analysis also shows tend older, suggesting age as contributing factor. These findings underscore need routine screening care, especially elderly patients.

Language: Английский

Prevalence of metabolic syndrome in patients with inflammatory bowel disease: a meta-analysis on a global scale DOI Creative Commons
Krishnamachari Janani, Parsa Saberian,

Hardik Patel

et al.

Journal of Health Population and Nutrition, Journal Year: 2025, Volume and Issue: 44(1)

Published: April 9, 2025

Metabolic syndrome (MetS) is a cluster of metabolic abnormalities that increase the risk cardiovascular diseases (CVD). Patients with inflammatory bowel disease (IBD) may be at higher developing MetS due to chronic inflammation, altered adipokine profiles, and effects corticosteroid treatment. However, prevalence in IBD patients remains inconsistent across studies. This meta-analysis aims estimate compare its occurrence between Crohn's (CD) ulcerative colitis (UC). A systematic search was conducted PubMed, Scopus, Embase, Web Science from their inception up January 19, 2025. Eligible observational studies reporting were included. Meta-analysis performed using random-effects model, heterogeneity assessed via I² statistic. Comprehensive Meta-Analysis (CMA) software, version 4.0 used for analysis. The pooled 21.8% (95% CI: 14.3-31.6%). UC (32.7%, 95% 16.0-55.5%) compared CD (14.1%, 8.6-22.3%). had significantly odds than those (OR = 1.38, 1.03-1.85, P 0.02). Additionally, older without (MD: 9.89, 5.12-14.67, < 0.01). In summary, this reveals notable among IBD, particularly UC, where CD. analysis also shows tend older, suggesting age as contributing factor. These findings underscore need routine screening care, especially elderly patients.

Language: Английский

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