Metaplastic neuromodulation via transcranial direct current stimulation has no effect on corticospinal excitability and neuromuscular fatigue DOI Creative Commons

Madison R. Boda,

Lavender A. Otieno, Ashleigh E. Smith

et al.

Experimental Brain Research, Journal Year: 2024, Volume and Issue: 242(8), P. 1999 - 2012

Published: June 28, 2024

Abstract Transcranial direct current stimulation (tDCS) is a non-invasive brain tool with potential for managing neuromuscular fatigue, possibly due to alterations in corticospinal excitability. However, inconsistencies intra- and inter- individual variability responsiveness tDCS limit its clinical use. Emerging evidence suggests harnessing homeostatic metaplasticity induced via may reduce boost outcomes, yet little known regarding influence on fatigue healthy adults. We explored whether cathodal (ctDCS) prior exercise combined anodal (atDCS) could augment excitability attenuate fatigue. 15 young adults (6 males, 22 ± 4 years) participated four pseudo-randomised neuromodulation sessions: sham during exercise, atDCS ctDCS exercise. The constituted an intermittent maximal voluntary contraction (MVC) of the right first dorsal interosseous (FDI) 10 min. Neuromuscular was quantified as attenuation MVC force, while motor evoked (MEP) amplitude provided assessment MEP increased fatiguing whilst across time, force decreased. There were no differences amplitudes or between sessions. These outcomes highlight ambiguity ameliorate individuals.

Language: Английский

Metaplastic neuromodulation via transcranial direct current stimulation has no effect on corticospinal excitability and neuromuscular fatigue DOI Open Access
Madison R Boda, Lavender A. Otieno, Ashleigh E. Smith

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 29, 2024

ABSTRACT Transcranial direct current stimulation (tDCS) is a non-invasive brain tool with potential for managing fatigue, possibly due to alterations in corticospinal excitability. However, inconsistencies intra– and inter-individual variability responsiveness tDCS limit its clinical use. Emerging evidence suggests harnessing homeostatic metaplasticity induced via may reduce boost outcomes, yet little known regarding influence on fatigue healthy adults. We explored whether cathodal (ctDCS) prior exercise combined anodal (atDCS) could augment excitability attenuate fatigue. 15 young adults (6 males, 22 ± 4 years) participated four pseudo-randomised neuromodulation sessions: sham during exercise, atDCS ctDCS exercise. The constituted an intermittent maximal voluntary contraction (MVC) of the right first dorsal interosseous (FDI) 10 minutes. Fatigue was quantified as attenuation MVC force, while motor evoked (MEP) amplitude provided assessment MEP increased fatiguing whilst across time, force decreased. There were no differences amplitudes or between sessions. These outcomes highlight ambiguity ameliorate individuals.

Language: Английский

Citations

0
Metaplastic neuromodulation via transcranial direct current stimulation has no effect on corticospinal excitability and neuromuscular fatigue DOI Creative Commons

Madison R. Boda,

Lavender A. Otieno, Ashleigh E. Smith

et al.

Experimental Brain Research, Journal Year: 2024, Volume and Issue: 242(8), P. 1999 - 2012

Published: June 28, 2024

Abstract Transcranial direct current stimulation (tDCS) is a non-invasive brain tool with potential for managing neuromuscular fatigue, possibly due to alterations in corticospinal excitability. However, inconsistencies intra- and inter- individual variability responsiveness tDCS limit its clinical use. Emerging evidence suggests harnessing homeostatic metaplasticity induced via may reduce boost outcomes, yet little known regarding influence on fatigue healthy adults. We explored whether cathodal (ctDCS) prior exercise combined anodal (atDCS) could augment excitability attenuate fatigue. 15 young adults (6 males, 22 ± 4 years) participated four pseudo-randomised neuromodulation sessions: sham during exercise, atDCS ctDCS exercise. The constituted an intermittent maximal voluntary contraction (MVC) of the right first dorsal interosseous (FDI) 10 min. Neuromuscular was quantified as attenuation MVC force, while motor evoked (MEP) amplitude provided assessment MEP increased fatiguing whilst across time, force decreased. There were no differences amplitudes or between sessions. These outcomes highlight ambiguity ameliorate individuals.

Language: Английский

Citations

0