Modified Huangfeng Decoction Alleviates Diabetic Nephropathy by Activating Autophagy and Regulating the Gut Microbiota

Phytomedicine, Journal Year: 2025, Volume and Issue: unknown, P. 156677 - 156677

Published: March 1, 2025

Language: Английский

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A Cascade of Microbiota-Leaky Gut-Inflammation- Is it a Key Player in Metabolic Disorders?

Current Obesity Reports, Journal Year: 2025, Volume and Issue: 14(1)

Published: April 10, 2025

Language: Английский

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Research progress on the microbial metabolism and transport of polyamines and their roles in animal gut homeostasis

Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology, Journal Year: 2025, Volume and Issue: 16(1)

Published: April 15, 2025

Abstract Polyamines (putrescine, spermidine, and spermine) are aliphatic compounds ubiquitous in prokaryotes eukaryotes. Positively charged polyamines bind to negatively macromolecules, such as nucleic acids acidic phospholipids, involved physiological activities including cell proliferation, differentiation, apoptosis gene regulation. Intracellular polyamine levels regulated by biosynthesis, catabolism transport. the body originate from two primary sources: dietary intake intestinal microbial metabolism. These then transported into bloodstream, through which they distributed various tissues organs exert their biological functions. synthesized microorganisms serve dual critical roles. First, essential for maintaining concentrations within digestive tract. Second, transcriptional post-transcriptional mechanisms, these microbial-derived modulate expression of genes governing key processes epithelial cells—including migration, apoptosis, cell–cell interactions. Collectively, regulatory effects help maintain homeostasis ensure integrity gut barrier. In addition, interact with microbiota promoting growth, biofilm formation, swarming, endocytosis vesicle production, etc. Supplementation has been demonstrated be important regulating host composition, enhancing nutrient absorption, improving metabolism immunity. this review, we will focus on recent advances study transport microbes cells. We summarize scientific understanding roles homeostasis, exploring cellular molecular mechanisms potential clinical applications, providing a rationale an target treatment intestinal-based diseases. Graphical

Language: Английский

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Association between dietary spermidine intake and cognitive performance in older adults: The U.S. National Health and Nutrition Examination Survey, 2011–2014

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

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Polyamine metabolism in macrophage–adipose tissue function and homeostasis

Trends in Endocrinology and Metabolism, Journal Year: 2024, Volume and Issue: 35(11), P. 937 - 950

Published: June 18, 2024

Language: Английский

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Phenotypic characteristics of adipocyte-like cells generated from C2C12 myoblasts cultured with chicken serum

Biochemical and Biophysical Research Communications, Journal Year: 2024, Volume and Issue: 736, P. 150843 - 150843

Published: Oct. 16, 2024

Language: Английский

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Cinnamon powder intake enhances the effect of caloric restriction on white adipose tissue in male rats

Journal of Molecular Histology, Journal Year: 2024, Volume and Issue: 56(1)

Published: Dec. 4, 2024

Language: Английский

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