Effects of sodium benzoate on cognitive function in neuropsychiatric disorders: a systematic review and meta-analysis DOI Creative Commons
Chun-Wei Liang, Hsiao-Yi Cheng, Mei‐Chih Meg Tseng

et al.

Frontiers in Psychiatry, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 9, 2024

We performed a systematic review and meta-analysis on sodium benzoate's effects cognitive function other psychiatric symptoms in individuals with neuropsychiatric disorders. searched PubMed, Embase, Cochrane Library, PsychInfo databases until September 2023. A random-effects was within frequentist framework. To investigate the potential sources of heterogeneity, we subgroup analyses based sex, dose, diagnosis, risk bias included studies. Trial sequential were to statistical power synthesized The certainty evidence evaluated using Grading Recommendations Assessment, Development Evaluation approach. total 10 studies analysis. Sodium benzoate demonstrated small-to-moderate positive effect global compared placebo (standardized mean difference 0.40, 95% confidence interval 0.20 0.60, high certainty). Subgroup suggested more pronounced women; receiving doses >500 mg/day; early-phase Alzheimer's disease, chronic schizophrenia, or major depressive disorder. also efficacy enhancing speed processing, working memory, verbal learning visual reasoning problem solving. Furthermore, effective for psychotic but not negative moderate certainty. current strongly supports Further research is required confirm its across different subtypes stages neurocognitive disorders specific domains.

Language: Английский

Effect of ultrasound on the structure and emulsion stability of insoluble undenatured type II collagen DOI

Mengman Wang,

Chaowei Ma,

Yan Li

et al.

Food Hydrocolloids, Journal Year: 2025, Volume and Issue: unknown, P. 111194 - 111194

Published: Feb. 1, 2025

Language: Английский

Citations

0
The Egyptian clinical practice guidelines for the diagnosis and management of knee osteoarthritis DOI Creative Commons
Mohamed Mortada, Mohammed Hassan Abu-Zaid, Ahmed Abogamal

et al.

Egyptian Rheumatology and Rehabilitation, Journal Year: 2025, Volume and Issue: 52(1)

Published: May 4, 2025

Abstract Background Knee osteoarthritis (KOA) is a widespread, debilitating condition that drastically impacts the quality of life and healthcare systems globally. In Egypt, burden KOA increasing due to an aging population, rising obesity rates, lifestyle factors. Recognizing urgent need for tailored recommendations, this article introduces Egyptian Clinical Practice Guidelines diagnosis management. These guidelines address Egypt's specific demographic, socioeconomic, challenges. Results The provide comprehensive framework diagnosing KOA, affirming clinical evaluation supported by imaging laboratory findings when necessary. They integrate global evidence-based practices with local expertise resources ensure relevance applicability. recommendations prioritize multidisciplinary approach, emphasizing patient-centered care through modifications, physical therapy, pharmacological interventions, appropriate use intra-articular therapies. For advanced cases unresponsive conservative measures, surgical options are outlined. Special attention given enhancing accessibility affordability treatments in alignment constraints system. Conclusion aim standardize management, facilitate early detection, improve patient outcomes across diverse settings. By offering clear, they serve as critical tool professionals, policymakers, stakeholders, significantly reducing Egypt.

Language: Английский

Citations

0
Effects of the combination of various pharmacological treatments and exercise on knee osteoarthritis: a systematic review and network meta-analysis DOI Creative Commons
Hsiao-Yi Cheng, Chun-Wei Liang, Yu-Hao Lee

et al.

EFORT Open Reviews, Journal Year: 2024, Volume and Issue: 9(7), P. 668 - 675

Published: July 1, 2024

Purpose The combination of pharmacological and non-pharmacological interventions is strongly recommended by current guidelines for knee osteoarthritis. However, few systematic reviews have validated their combined efficacy. In this study, we investigated the effects agents exercise on Methods Randomized controlled trials that efficacy with osteoarthritis were searched in PubMed, Embase, Cochrane Library up to February 2024. network meta-analysis was performed within frequentist framework. Standardized mean difference (SMD) 95% CI estimated pain function. Grading recommendations, assessment, development, evaluations used evaluate certainty evidence. Results total, 71 studies included. therapy outperformed or alone. Among various exercise, mesenchymal stem cell injection ranked best short-term reduction (SMD: −1.53, CI: −1.92 −1.13, high certainty), followed botulinum toxin A, dextrose, platelet-rich plasma. For long-term relief, dextrose prolotherapy optimal −1.76, −2.65 −0.88, moderate cells, platelet rich growth factor, Conclusion Exercise programs should be incorporated into clinical practice trial design. patients undergoing therapies, cell, plasma, A may agents.

Language: Английский

Citations

1
Effects of sodium benzoate on cognitive function in neuropsychiatric disorders: a systematic review and meta-analysis DOI Creative Commons
Chun-Wei Liang, Hsiao-Yi Cheng, Mei‐Chih Meg Tseng

et al.

Frontiers in Psychiatry, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 9, 2024

We performed a systematic review and meta-analysis on sodium benzoate's effects cognitive function other psychiatric symptoms in individuals with neuropsychiatric disorders. searched PubMed, Embase, Cochrane Library, PsychInfo databases until September 2023. A random-effects was within frequentist framework. To investigate the potential sources of heterogeneity, we subgroup analyses based sex, dose, diagnosis, risk bias included studies. Trial sequential were to statistical power synthesized The certainty evidence evaluated using Grading Recommendations Assessment, Development Evaluation approach. total 10 studies analysis. Sodium benzoate demonstrated small-to-moderate positive effect global compared placebo (standardized mean difference 0.40, 95% confidence interval 0.20 0.60, high certainty). Subgroup suggested more pronounced women; receiving doses >500 mg/day; early-phase Alzheimer's disease, chronic schizophrenia, or major depressive disorder. also efficacy enhancing speed processing, working memory, verbal learning visual reasoning problem solving. Furthermore, effective for psychotic but not negative moderate certainty. current strongly supports Further research is required confirm its across different subtypes stages neurocognitive disorders specific domains.

Language: Английский

Citations

1