Artificial intelligence (AI)-powered bibliometric analysis of global trends in mesenchymal stem cells (MSCs)-derived exosome research: 2014-2023 DOI Creative Commons
Shih‐Chang Tsai, B. Y. C. Wan,

Fuu‐Jen Tsai

et al.

Biomedicine, Journal Year: 2024, Volume and Issue: 14(4)

Published: Dec. 1, 2024

Introduction: In recent years, significant progress has been made in regenerative medicine, specifically using mesenchymal stem cells (MSCs) due to their and differentiating abilities. An exciting development this area is the utilization of exosomes derived from MSCs, which have shown promise tissue restoration, immune system modulation, cancer treatment.

Language: Английский

Mesenchymal Stromal Cell-Based Therapy: A Promising Approach for Autoimmune Diseases DOI
Liming Li, Yong He,

Junpeng Zhao

et al.

Clinical Reviews in Allergy & Immunology, Journal Year: 2025, Volume and Issue: 68(1)

Published: Feb. 21, 2025

Language: Английский

Citations

0
Improvement in long-term survival with mesenchymal stem cell transplantation in systemic sclerosis patients: a propensity score-matched cohort study DOI Creative Commons
Wenyi Yuan, Mian Liu, Dapeng Yang

et al.

Stem Cell Research & Therapy, Journal Year: 2025, Volume and Issue: 16(1)

Published: March 9, 2025

The intricate and varied clinical presentations of systemic sclerosis (SSc) pose significant challenges for treatment. While several studies have investigated the therapeutic potential mesenchymal stem cell transplantation (MSCT), clarity its long-term outcomes SSc patients is still lacking. Data on MSCT were extracted from medical records inpatients at Nanjing Drum Tower Hospital between January 2013 December 2022. Additionally, Baseline characteristics survival ascertained telephone follow-up. Propensity score matching (PSM) was employed to equalize baseline patient groups, while analysis multivariate Cox regression assessed relationship received all-cause mortality disease-specific rates in patients. Of 333 hospitalized patients, 113 underwent MSCT. log-rank test revealed significantly higher group compared control (10-year rate 89.4% vs. 73.4%, P = 0.002). In PSM cohort, receiving reduced 88.0% 79.9%, 0.032). Multivariate indicated that linked a risk during follow-up period (HR 0.38, 95% CI 0.19–0.75, 0.005). This finding further confirmed matched cohort 0.18–0.82, 0.014). Subgroup analyses treated with correlated various demographics, including younger age diagnosis (≤ 47 years), female, diffuse cutaneous (dcSSc) subtype, concurrent arthritis, pulmonary arterial hypertension (PAH), interstitial lung disease (ILD). enhances SSc, related diagnosis. particularly comorbid conditions, PAH, ILD, digital ulcers, as well those severe associated dcSSc subtype.

Language: Английский

Citations

0
Leveraging engineered yeast small extracellular vesicles serve as multifunctional platforms for effectively loading methyl salicylate through the “esterase-responsive active loading” strategy DOI
Tianhao Li, Yun Zhou, Haoran Wang

et al.

European Journal of Pharmaceutics and Biopharmaceutics, Journal Year: 2025, Volume and Issue: unknown, P. 114696 - 114696

Published: March 1, 2025

Language: Английский

Citations

0
The multifaceted roles of extracellular vesicles in osteonecrosis of the femoral head DOI

Hongxu Li,

Haoyang Liu, Yu Zhou

et al.

Journal of Orthopaedic Translation, Journal Year: 2025, Volume and Issue: 52, P. 70 - 84

Published: April 10, 2025

Language: Английский

Citations

0
Addressing musculoskeletal disorders through new treatment strategies DOI Creative Commons

Heng Sun,

Bin Li,

Huilin Yang

et al.

Journal of Orthopaedic Translation, Journal Year: 2024, Volume and Issue: 48, P. A1 - A2

Published: Sept. 1, 2024

Language: Английский

Citations

0
Artificial intelligence (AI)-powered bibliometric analysis of global trends in mesenchymal stem cells (MSCs)-derived exosome research: 2014-2023 DOI Creative Commons
Shih‐Chang Tsai, B. Y. C. Wan,

Fuu‐Jen Tsai

et al.

Biomedicine, Journal Year: 2024, Volume and Issue: 14(4)

Published: Dec. 1, 2024

Introduction: In recent years, significant progress has been made in regenerative medicine, specifically using mesenchymal stem cells (MSCs) due to their and differentiating abilities. An exciting development this area is the utilization of exosomes derived from MSCs, which have shown promise tissue restoration, immune system modulation, cancer treatment.

Language: Английский

Citations

0