A Prediction Model for the Diagnosis of Sepsis Based on the Classification of Acute Gastrointestinal Injury
Sun Yu,
No information about this author
Chunyang Xu,
No information about this author
Shun Wen
No information about this author
et al.
British Journal of Hospital Medicine,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 19
Published: May 19, 2025
Aims/Background
The
existing
screening
approaches
for
sepsis
demonstrate
lower
sensitivity,
potentially
resulting
in
misdiagnosis
of
septic
conditions.
gastrointestinal
tract
is
the
primary
and
most
susceptible
organ
during
sepsis.
Therefore,
this
study
aims
to
establish
evaluate
a
predictive
model
based
on
classification
acute
injury
(AGI),
improve
diagnostic
sensitivity.
Methods
This
retrospective
included
patients
with
confirmed
infections
or
suspected
who
were
admitted
general
ward
Changshu
Hospital
Affiliated
Soochow
University
(Changshu
First
People's
Hospital,
China)
between
April
2023
December
2023.
Patients
randomly
divided
into
developing
cohort
(n
=
1667)
validation
712)
7:3
ratio.
Furthermore,
data
collected
various
variables,
including
inflammatory
factors,
hemodynamic
dysfunction
tissue
perfusion
variables.
Univariate
analysis
was
used
screen
risk
factors
associated
sepsis,
logistic
regression
employed
identify
independent
factors.
nomogram
constructed
these
Additionally,
prediction
significance
evaluated
using
receiver
operating
characteristic
(ROC)
curves,
calibration
decision
curve
(DCA)
across
both
cohorts.
Results
Out
total
2379
study,
rate
12.5%.
incidence
AGI
96.0%,
23.2%
grade
I,
52.3%
II,
16.1%
III,
4.4%
IV.
Factors
like
age
(Odds
Ratio
(OR)
1.029,
95%
Confidence
Interval
(CI)
1.015–1.043,
p
<
0.01),
hypotension
(OR
3.863,
CI
2.372–6.290,
oxygen
saturation
(SpO
2
)
0.795,
0.751–0.840,
thrombocytopenia
5.657,
2.835–11.289,
0.01)
7.151,
5.040–10.144,
observed
as
predictors
Based
five
(model
B)
developed.
Model
B
achieved
area
under
(AUC)
0.947
(95%
0.932–0.963)
0.962
0.945–0.978)
cohorts,
respectively,
which
significantly
higher
than
AUC
value
quick
Sequential
Organ
Failure
Assessment
(qSOFA)
A).
curves
datasets
close
ideal
model.
Decision
revealed
that
exhibited
better
net
clinical
benefit
A.
Conclusion
developed
validated
novel
could
predict
wards,
helping
decision-making.
Language: Английский
Machine Learning Models as Early Warning Systems for Neonatal Infection
Clinics in Perinatology,
Journal Year:
2024,
Volume and Issue:
52(1), P. 167 - 183
Published: Nov. 27, 2024
Language: Английский
Heart rate analysis in neonatal sepsis: a complex equation
Pediatric Research,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 6, 2024
Language: Английский
Control of Breathing in Preterm Infants
Seminars in Fetal and Neonatal Medicine,
Journal Year:
2024,
Volume and Issue:
unknown, P. 101559 - 101559
Published: Nov. 1, 2024
Language: Английский
Reimagining apnea monitoring in the neonatal ICU
Emily Jeanne,
No information about this author
Ruben Alvaro,
No information about this author
Wissam Shalish
No information about this author
et al.
Current Opinion in Pediatrics,
Journal Year:
2024,
Volume and Issue:
37(2), P. 173 - 181
Published: Dec. 11, 2024
This
review
outlines
the
prevalence
and
complications
of
apneas
intermittent
hypoxemic
events
in
preterm
infants,
examines
current
monitoring
limitations
neonatal
ICUs
(NICUs),
explores
emerging
technologies
addressing
these
challenges.
New
evidence
from
Prematurity-Related
Ventilatory
Control
(Pre-Vent)
study,
which
analyzed
cardiorespiratory
data
717
extremely
exposes
varying
frequency,
duration,
severity
apneas,
hypoxemia,
bradycardias,
periodic
breathing
during
hospitalization,
highlights
negative
impact
hypoxemia
on
pulmonary
outcomes
at
discharge.
Although
traditional
methods
cannot
differentiate
between
apnea
types
quantify
their
burden,
recent
advancements
sensor
integration
hold
promise
for
improving
real-time
detection
evaluation
NICU.
Notably,
small
wearable
mechano-acoustic
sensors
could
improve
through
continuous
airflow
respiratory
efforts.
Additionally,
integrating
bedside
physiological
with
modalities
such
as
near-infrared
spectroscopy,
diaphragmatic
activity,
electrical
impedance
tomography
help
predict
adverse
by
regional
oxygen
saturation
lung
function
relation
to
apneas.
Enhancing
our
understanding
overcoming
advanced
lead
more
personalized
management
improved
infants.
Language: Английский