Molecules,
Journal Year:
2022,
Volume and Issue:
27(22), P. 8021 - 8021
Published: Nov. 18, 2022
The
poor
water
solubility,
large
particle
size,
and
low
accessibility
of
cellulose,
the
most
abundant
bioresource,
have
restricted
its
generalization
to
carbon
dots
(CDs).
Herein,
nitrogen
sulfur
co-doped
fluorescent
(N,
S-CDs)
were
hydrothermally
synthesized
using
cellulose
nanocrystals
(CNC)
as
a
precursor,
exhibiting
small
size
excellent
aqueous
dispersion.
Thiourea
was
selected
dopant
introduce
functional
groups
into
N,
S-CDs.
resulting
S-CDs
exhibited
nanoscale
(6.2
nm),
groups,
bright
blue
fluorescence,
high
quantum
yield
(QY
=
27.4%),
overall
(16.2%).
optical
properties
endowed
it
potentially
display
highly
sensitive
fluorescence
"turn
off"
response
rutin.
for
rutin
allowed
wide
linear
range
0-40
mg·L-1,
with
limit
detection
(LOD)
0.02
μM,
which
revealed
potential
rapid
simple
sensing
platform
detection.
In
addition,
sustainable
large-scale
production
in
this
study
paves
way
successful
high-value
utilization
cellulose.
Nanomaterials,
Journal Year:
2021,
Volume and Issue:
11(8), P. 1877 - 1877
Published: July 22, 2021
Antimicrobial
resistance
is
a
recognized
global
challenge.
Tools
for
bacterial
detection
can
combat
antimicrobial
by
facilitating
evidence-based
antibiotic
prescribing,
thus
avoiding
their
overprescription,
which
contributes
to
the
spread
of
resistance.
Unfortunately,
traditional
culture-based
identification
methods
take
at
least
day,
while
emerging
alternatives
are
limited
high
cost
and
requirement
skilled
operators.
Moreover,
photodynamic
inactivation
bacteria
promoted
photosensitisers
could
be
considered
as
one
most
promising
strategies
in
fight
against
multidrug
pathogens.
In
this
context,
carbon
dots
(CDs)
have
been
identified
class
photosensitiser
nanomaterials
specific
different
species.
CDs
possess
exceptional
tuneable
chemical
photoelectric
properties
that
make
them
excellent
candidates
antibacterial
theranostic
applications,
such
great
stability,
water
solubility,
low
toxicity
biocompatibility.
review,
we
will
summarize
recent
advances
on
use
agents,
including
commonly
used
methodologies
CD
CD/composites
syntheses
both
vitro
vivo
models
developed
last
3
years.
Pharmaceuticals,
Journal Year:
2021,
Volume and Issue:
14(11), P. 1201 - 1201
Published: Nov. 22, 2021
One
of
the
major
impediments
to
drug
development
is
low
aqueous
solubility
and
thus
poor
bioavailability,
which
leads
insufficient
clinical
utility.
Around
70-80%
drugs
in
discovery
pipeline
are
suffering
from
a
challenge
when
one
has
develop
an
ocular
delivery
system.
The
outer
lipid
layer,
pre-corneal,
dynamic,
static
barriers
limit
availability
targeted
tissues.
Biopharmaceutical
Classification
System
(BCS)
class
II
with
adequate
permeability
limited
or
no
have
been
extensively
studied
for
various
polymer-based
enhancement
approaches.
hydrophilic
nature
cellulosic
polymers
their
tunable
properties
make
them
choice
solubility-enhancement
techniques.
This
review
focuses
on
cellulose
derivatives,
specifically,
role,
current
status
novel
modified
enhancing
bioavailability
BCS
systems.
Exploration,
Journal Year:
2023,
Volume and Issue:
3(6)
Published: Oct. 2, 2023
Abstract
Biomass
with
abundant
reproducible
carbon
resource
holds
great
promise
as
an
intriguing
substitute
for
fossil
fuels
in
the
manufacture
of
high‐value‐added
chemicals
and
fuels.
Photocatalytic
biomass
valorization
using
inexhaustible
solar
energy
enables
to
accurately
break
desired
chemical
bonds
or
selectively
functionalize
particular
groups,
thus
emerging
extremely
creative
low
cost
strategy
relieving
dilemma
global
energy.
Quantum
dots
(QDs)
are
outstandingly
dynamic
class
semiconductor
photocatalysts
because
their
unique
properties,
which
have
achieved
significant
successes
various
photocatalytic
applications
including
valorization.
In
this
review,
current
development
rational
design
QDs
effectively
is
highlighted,
focusing
on
principles
tuning
particle
size,
structure,
surface
special
emphasis
effect
ligands
broken
(C─O,
C─C)
biomass.
Finally,
present
issues
possibilities
within
that
exciting
field
described.
Biotechnology and Bioengineering,
Journal Year:
2024,
Volume and Issue:
121(5), P. 1469 - 1485
Published: March 28, 2024
Abstract
The
carbon‐based
nanostructures
have
led
to
the
development
of
theranostic
nanoplatforms
for
simultaneous
diagnosis
and
therapy
due
their
effective
cell
membrane‐penetration
ability,
low
degree
cytotoxicity,
excellent
pore
volume,
substantial
chemical
stability,
reactive
surface.
In
last
few
years,
extensive
efforts
were
made
design
multifunctional
nanoplatform
strategies
based
on
carbon
nanostructures,
involving
multimodal
imaging,
controlled
drug
release
capabilities,
sensing
in
vitro,
efficient
loading
capacity,
therapy.
Carbon
graphene
quantum
dots
(CQDs
GQDs)
recent
entrants,
contingently
being
assessed
delivery
bioimaging.
With
advancements,
these
ignited
remarkable
research
interest
are
now
widely
evaluated
diagnosis,
bioimaging,
sensing,
applications.
decade
has
witnessed
electrical,
optical,
biocompatible
properties
since
inception.
It
is
presumed
that
both
them
high
potential
as
carriers
would
serve
next
generation
approaches
address
numerous
unresolved
therapeutic
challenges.
This
review
examined
advances
CQD
GQD
applications,
challenges,
future
perspectives
pave
way
further
studies
future.