Psychedelics and workplace harm

Frontiers in Psychiatry, Journal Year: 2023, Volume and Issue: 14

Published: June 16, 2023

This study aims to understand the relationship between Lifetime Classic Psychedelic Use (LCPU), employment status, and weekly work hours on levels of psychological distress. The data used for this analysis is pooled from National Survey Drug Health (NSDUH) 2008-2019 includes a sample size 484,732 individuals. findings suggest that LCPU being employed are independently associated with better health. Additionally, results indicate psychedelic use lower distress those who employed, volunteer, retired, or permanently disabled. However, unemployed, full-time students, homemakers may experience higher use. Interestingly, also suggests psychedelics working longer per week before experiencing an increase in stress. Overall, not likely have negative impact outcomes.

Language: Английский

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Religion, Psychedelics, Risky Behavior, and Violence

Journal of Psychoactive Drugs, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 12

Published: April 25, 2024

Research has found that psychedelic use is associated with positive behavioral changes, however research yet to explore the relationship between socio-cultural conditions on this relationship. This paper intends fill gap by testing effects of religious participation and beliefs behaviors. study examines Lifetime Classic Psychedelic Use (LCPU), different aspects religion (such as salience attendance), likelihood committing a violent assault. The analysis uses pooled data from National Survey Drug Health (NSDUH) 2015 2019, sample size 282,768. Binary logistic regression models conducted in Stata 17 reveal LCPU (salience influence) are independently reduced violence. Additionally, two-way interactions indicate association risky behavior violence smaller among individuals high levels salience. Furthermore, three-way interaction suggests for those who have used psychedelics, largest effect observed These results show factors can influence behaviors, both attendance operating simultaneously.

Language: Английский

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Ketamine as a Novel Psychopharmacotherapy for Eating Disorders: Evidence and Future Directions

Brain Sciences, Journal Year: 2022, Volume and Issue: 12(3), P. 382 - 382

Published: March 12, 2022

Eating disorders (EDs) are serious, life-threatening psychiatric conditions associated with physical and psychosocial impairment, as well high morbidity mortality. Given the chronic refractory nature of EDs paucity evidence-based treatments, there is a pressing need to identify novel approaches for this population. The noncompetitive N-methyl-D-aspartate receptor (NMDAr) antagonist, ketamine, has recently been approved treatment-resistant depression, exerting rapid robust antidepressant effects. It now being investigated several new indications, including obsessive–compulsive, post-traumatic, substance use disorder, shows transdiagnostic potential EDs, particularly among clinical nonresponders. Hence, aim review examine contemporary findings on treatment whether used primary, adjunctive, or combination psychopharmacotherapy. Avenues future research also discussed. Overall, results encouraging point therapeutic value; however, limited case series reports anorexia nervosa. Further empirical thus needed explore ketamine efficacy across ED subgroups, establish safety profiles optimize dosing, develop theory-driven, targeted strategies at individual patient level.

Language: Английский

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Minorities’ Diminished Psychedelic Returns: Gender, Perceived Stigma, and Distress

Psychoactives, Journal Year: 2024, Volume and Issue: 3(2), P. 303 - 317

Published: June 2, 2024

Because psychedelics have been found to increase psychological traits like openness, mental flexibility, and interpersonal perceptiveness, some researchers believe that could help individuals cope with the effects of discrimination. However, it is still unclear whether psychedelic use can manage internalized stigma deters formal health treatment. This study investigates impact six measures (MDMA, psilocybin, DMT, ayahuasca, peyote/mescaline, LSD) on distress (Kessler Psychological Distress Scale) stigma. The used data from National Survey Drug Use Health (NSDUH) 2008 2019, a sample size 458,372 participants. Ordinary least square regression models were conducted using Stata 18. Gender analysis among men, ayahuasca was linked reduced perception associated higher distress. For women, DMT perceptions when experiencing results find who MDMA psilocybin reported heightened increased Among they experienced These findings suggest that, overall, may not reduce stigma, especially for women.

Language: Английский

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Psychedelic-Assisted Therapy for People with Eating Disorders

Current Psychiatry Reports, Journal Year: 2022, Volume and Issue: 24(12), P. 767 - 775

Published: Nov. 14, 2022

Language: Английский

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Therapeutic uses of psychedelics for eating disorders and body dysmorphic disorder

Journal of Psychopharmacology, Journal Year: 2022, Volume and Issue: 37(1), P. 3 - 13

Published: Dec. 14, 2022

Background: Clinical use of psychedelics has gained considerable attention, with promising benefits across a range mental disorders. Current pharmacological and psychotherapeutic treatments for body dysmorphic disorder (BDD) eating disorders (EDs) have limited efficacy. As such, other treatment options such as psychedelic-assisted therapies are being explored in these clinical groups. Aims: This systematic review evaluates evidence related to the therapeutic potential individuals diagnosed BDD EDs. Methods: Following Preferred Reporting Items Systematic Reviews Meta-Analyses guidelines, we conducted all study designs published end February 2022 that identified changes ED/BDD symptom severity from using validated measures assess changes. Results: Our search detected total 372 studies, which five met inclusion criteria (two exploratory two case reports, one prospective study). These were included data evaluation. Effects on various ED symptoms mostly through thematic analyses self-reports. Conclusions: findings highlight more research is needed determine safety efficacy EDs suggest avenues future exploration.

Language: Английский

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Biological treatments for co-occurring eating disorders and psychological trauma: a systematic review

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 21, 2025

Introduction Many people with eating disorders report having experienced childhood maltreatment or a traumatic event prior to developing an disorder. Although many have significant exposure symptoms of post-traumatic stress disorder, very little research has examined the effects combined treatments for this group. The purpose systematic review was synthesize all existing on biological those and psychological trauma, evaluate their safety, identify future areas in area support patients trauma. Method A multi-step literature search, according priori protocol performed PubMed, Embase, APA PsycINFO, Web Science, Scopus Cochrane Central. Studies needed include intervention at least one disorder trauma outcome. Given limited area, minimal exclusion criteria were applied. quality assessment included studies completed using Risk Bias Non-Randomized Studies-or Interventions (ROBINS-I) tool. Results After removing duplicates, 2623 article titles abstracts screened, 43 articles selected full-text review. Following review, 11 met inclusion criteria. repurposed medications (n = 3), ketamine 2), repetitive transcranial magnetic stimulation (rTMS; n deep brain =1) electroconvulsive therapy (ECT; 1), 3,4-methylenedioxymethamphetamine (MDMA; neurofeedback 1). All reported some improvement either pathology, strongest effect MDMA. While promising, missing data selective reporting interpretability findings. Adverse events across interventions common. Conclusion is common disorders, few been evaluated population. Future work should aim investigate co-occurring as these evolving show potential benefits complex

Language: Английский

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Exploring the Role of Psychedelic Experiences on Wellbeing and Symptoms of Disordered Eating

Psychoactives, Journal Year: 2025, Volume and Issue: 4(1), P. 7 - 7

Published: March 4, 2025

Accumulating psychedelic research has demonstrated a potential for improving mental health and wellbeing, yet studies in the context of eating disorders (EDs) are limited. This study aims to explore subjective effects experiences gain insight into benefits risks people with EDs. Semi-structured interviews were conducted eight adults aged 25–54 (mean age = 36.9), reporting have had EDs psychedelics both naturalistic clinical settings. Participants multiple diagnoses suffered chronic EDs, onset 13), diagnosed (N 7) undiagnosed 1). Reports cessation or reduction ED symptoms unanimous long-lasting seven, two participants recovery attributed use. Two reported relapsing, environmental factors months following. Thematic analysis resulted superordinate themes, each comprising three subordinate themes. The first theme, ‘Exploring’ via ‘gateway healing’, illustrates mental, emotional, transcendental elements experiences. second ‘Transformation’ being ‘able do work’, cognitive behavioural outcomes, retrospective safety perceptions. These findings may provide more in-depth information on what can obtain from use drugs inform robust investigations psychedelic-assisted therapy treatment

Language: Английский

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Educational moderation of gender disparities in psychedelic health outcomes

Published: March 6, 2025

While public interest in psychedelics is rising due to their potential effects on mental health, evidence suggests that these associations vary across demographic groups. Notably, prior research indicates women may experience different outcomes from psychedelic use compared men. Given highly educated tend have superior health general, this study examines whether education modifies the association between Lifetime Classic Psychedelic Use (LCPU) and psychological distress. Using pooled data National Survey of Drug Health (NSDUH) (2008–2019) (n = 458,372), applies nested Ordinary Least Square Regression (OLS) regression models Stata 18. Results three-way interaction terms indicate while LCPU associated with higher distress overall, varies levels. This pattern rather than universally improving depend key social factors such as gender.

Language: Английский

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A systematic review of income and education reporting in psychedelic clinical trials

Nature Mental Health, Journal Year: 2025, Volume and Issue: 3(5), P. 567 - 574

Published: May 12, 2025

Language: Английский

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