Journal of Psychiatric Research, Journal Year: 2024, Volume and Issue: 181, P. 188 - 196
Published: Nov. 26, 2024
Language: Английский
Frontiers in Neurology, Journal Year: 2025, Volume and Issue: 16
Published: Feb. 5, 2025
Stroke is a significant health threat, and its complex interplay with fractures warrants further investigation. Depression, critical psychological mediator in various conditions, may also play role. This study aims to clarify the intricate relationships among stroke, depressive symptoms, fracture risk, potentially informing more holistic clinical strategies. Utilizing most recent data from National Health Nutrition Examination Survey (NHANES, 2017 2020), this encompassed 4,979 valid samples. T-test chi square test are conducted compare differences between non subgroups. Subsequently, regression models were applied assess mediating impact of depression, Sobel's bootstrap method deployed substantiate mediation pathways. In study, we subgroup analyses investigate factors influencing stroke patients using NHANES data. Subgroup analysis revealed associations gender, race, osteoporosis, depression. Female had higher rate (73.86% vs. 47.78%, p < 0.001), those post-stroke depression (29.67% 13.16%, 0.001) or osteoporosis (33.33% 15.81%, 0.05) at increased risk fractures. Logistic showed positive association unadjusted (OR = 1.862, 95% CI: 1.348-2.573, adjusted I 1.789, 1.240-2.581, 0.01), but not II model. Depression was significantly correlated all (unadjusted OR 2.785, 1.271-6.101, 0.05; Model 1 3.737, 1.470-9.498, 0.01; 2 3.068, 1.026-9.175, 0.05). Mediation Sobel tests indicated that mediates 7.657% relationship (Z 2.31, 0.05), indirect 2.80, direct 3.61, total effects 3.92, 0.01). The effect on 0.079 (95% 0.036-0.121), 0.085 0.043-0.128), mediated by symptoms 0.007 0.002-0.011). These results suggest following contribute an Depressive serve as link risk. Consequently, our concludes prevention strategies for must incorporate focus mental effectively address challenge.
Language: Английский
Citations
0
Phytotherapy Research, Journal Year: 2025, Volume and Issue: unknown
Published: March 13, 2025
ABSTRACT In recent years, numerous researchers have focused on plant extracts derived from traditional medicines to treat stroke, as these may improve patients' cognitive function and quality of life. This study aims evaluate the effects nine distinct ( Ginkgo biloba extract, Ginsenosides, Berberine, St. John's Wort Resveratrol, Gastrodin, Crocus sativus L., Moringa oleifera Seed Panax Notoginseng Saponins) life in stroke patients. seeks conduct a network meta‐analysis assess impact Researchers systematically searched Embase, PubMed, Cochrane Library, Web Science databases database inception through October 2024 for randomized controlled trials (RCTs) exclusively(no language restrictions). The selected studies were evaluated methodological via bias risk assessment tool, data analysis software was used analyze accordingly. primary outcome measures included following scales: National Institute Health Stroke Scale (NIHSS), Modified Rankin (mRS), Activities Daily Living (ADLs), Barthel Index (BI), Montreal Cognitive Assessment (MOCA), Mini‐Mental State Examination (MMSE). Treatment ranked based probability values surface under cumulative ranking curve (SUCRA). Moreover, cluster applied six scales that reflect After screening, 48 eligible included, covering 6599 patients evaluating different extract treatments. Specifically, results 33 NIHSS score, 10 mRS 11 ADL BI MMSE eight MOCA score. Findings indicate (SUCRA 71.2%) most effective reducing scores, Berberine 84.1%) 99.1%) showed highest efficacy enhancing scores. Ginsenosides improving 74.7%), 93%), 79.7%) NMA indicates that, compared placebo, can enhance provides valuable insights into using treatment, potentially guiding clinical practice, but there are some unavoidable limitations our study, including heterogeneity, differences extraction methods extracts, lack consideration social support systems dose effects. Future longer follow‐up, larger samples, more methodologically rigorous recommended clearly establish dosages
Language: Английский
Citations
0
Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12
Published: April 9, 2025
The Life's Simple 7 (LS7) metric is a comprehensive index evaluating cardiovascular health from holistic perspective, integrating seven cardiovascular-related factors and behaviors. However, the relationship between LS7 likelihood of developing osteoarthritis (OA) remains unclear. Therefore, this study investigated possible association OA. Using data National Health Nutrition Examination Survey 2009 to 2018, 19,603 participants were included in study. was treated as independent variable, whereas OA served dependent variable. assessed by performing weighted logistic regression analysis. To evaluate stability findings, subgroup analyses conducted. Additionally, restricted cubic spline (RCS) analysis conducted explore potential nonlinear relationships scores significantly negatively correlated with risk (OR: 0.808, 95% CI: 0.786-0.830). Analysis categories indicated that individuals ideal had 55.9% lower than those poor 0.559, 0.379-0.823). Subgroup demonstrated such age, gender, marital status, BMI, blood pressure moderated inconsistent ways. RCS revealed significant negative (p-nonlinear < 0.001). This suggests correlation risk, implying better may be linked reduced varies across different subgroups.
Language: Английский
Citations
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Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)
Published: April 10, 2025
A substantial body of evidence indicates that stroke is a primary cause death and disability on global scale. The presence post-stroke depression has been demonstrated to exert influence the prognosis patients, underscoring imperative for identification early prevention depression. objective this study was examine association between cardiac history (PSD) in Chinese with aim identifying high-risk groups, promoting intervention strategies, enhancing patient prognosis. This based data from 2020 China Health Retirement Longitudinal Study (CHARLS), which included 933 respondents stroke. Univariate multivariate logistic regression analyses were used assess effects other variables (PSD). results indicated correlation In addition, showed gender, activities daily living (ADLs), cognitive functioning, life satisfaction also had an effect findings presented here indicate patients disease are more likely develop provides valuable insights into clinical management emotional health assessment such should be emphasized management, appropriate psychological support interventions provided improve their overall
Language: Английский
Citations
0
Journal of Psychiatric Research, Journal Year: 2024, Volume and Issue: 181, P. 188 - 196
Published: Nov. 26, 2024
Language: Английский
Citations
0