Sex-specific association between maternal childhood adversities and offspring’s weight gain in a Brazilian cohort DOI Creative Commons
Vilma Sousa Santana, Aline Camargo Ramos, Hugo Cogo‐Moreira

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 23, 2025

Abstract Maternal adverse childhood experiences (ACEs) are linked to negative health and developmental outcomes in offspring. However, whether maternal ACEs influence infant weight gain the first months of life, if this effect differs by sex, remains unclear. This study included 352 full-term newborns from low-risk pregnancies their mothers low-income settings Brazil. Anthropometric data (weight, length, head circumference) other information (feeding type, offspring family income) were collected at delivery (W0), discharge (W1), up 8 weeks postpartum (W2). assessed using CDC-Kaiser Questionnaire, was calculated as difference between W2 W1, divided number days measurements. The association positive only male (unstandardized coefficient (male) = 1.82, SE 0.438, p < 0.001); for each 1-point increase score (e.g., 0 1), increased 1.8 g/day. These findings indicate that associated with infants during two potentially increasing risk future obesity. Further research is required investigate underlying biological mechanisms neurodevelopmental implications.

Language: Английский

Sex-specific association between maternal childhood adversities and offspring’s weight gain in a Brazilian cohort DOI Creative Commons
Vilma Sousa Santana, Aline Camargo Ramos, Hugo Cogo‐Moreira

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 23, 2025

Abstract Maternal adverse childhood experiences (ACEs) are linked to negative health and developmental outcomes in offspring. However, whether maternal ACEs influence infant weight gain the first months of life, if this effect differs by sex, remains unclear. This study included 352 full-term newborns from low-risk pregnancies their mothers low-income settings Brazil. Anthropometric data (weight, length, head circumference) other information (feeding type, offspring family income) were collected at delivery (W0), discharge (W1), up 8 weeks postpartum (W2). assessed using CDC-Kaiser Questionnaire, was calculated as difference between W2 W1, divided number days measurements. The association positive only male (unstandardized coefficient (male) = 1.82, SE 0.438, p < 0.001); for each 1-point increase score (e.g., 0 1), increased 1.8 g/day. These findings indicate that associated with infants during two potentially increasing risk future obesity. Further research is required investigate underlying biological mechanisms neurodevelopmental implications.

Language: Английский

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