Progress of Kai-Xin-San in treating AD and depression: The possibility of "Homotherapy for Heteropathy" DOI Creative Commons
Chang Liu, Jingji Wang, Guoqi Zhu

et al.

Pharmacological Research - Modern Chinese Medicine, Journal Year: 2025, Volume and Issue: unknown, P. 100589 - 100589

Published: Feb. 1, 2025

Language: Английский

Bioactive compounds from Chinese herbal plants for neurological health: mechanisms, pathways, and functional food applications DOI Creative Commons
Meng Wang, Chao Wang,

Zhao Kaiwei

et al.

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: Jan. 31, 2025

Neurological disorders pose significant global public health challenges, with a rising prevalence and complex pathophysiological mechanisms that impose substantial social economic burdens. Traditional Chinese Medicine (TCM), its holistic approach multi-target effects, has gained increasing attention in the treatment of neurological diseases. This review explores bioactive compounds derived from herbal plants, focusing on their action, underlying pathways, potential applications functional food development. The highlights neuroprotective properties flavonoids, alkaloids, polysaccharides, polyphenols found key TCM herbs such as Scutellaria baicalensis , Salvia miltiorrhiza Ligusticum chuanxiong Gastrodia elata . These have demonstrated anti-inflammatory, antioxidant, neurogenic making them promising candidates for prevention conditions, including Alzheimer’s disease (AD), Parkinson’s (PD), depression. Furthermore, synergistic effects formulations targeting multiple signaling pathways offer advantages over single-target therapies, especially combating neurodegenerative also discusses challenges future directions integrating these into foods dietary supplements, aiming to improve enhance clinical outcomes. Ultimately, this work aims provide valuable insights TCM-based interventions promoting well-being addressing burden disorders.

Language: Английский

Citations

3
Acori Tatarinowii Rhizoma regulates OCT3/OATP2 and P-gp/MRP1 to “guide medicines upwards” in Kai-Xin-San to treat Alzheimer’s disease DOI
Junying Li,

Xiaoxiao Shan,

Yu Gao

et al.

Journal of Ethnopharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 119484 - 119484

Published: Feb. 1, 2025

Language: Английский

Citations

1
Progress of Kai-Xin-San in treating AD and depression: The possibility of "Homotherapy for Heteropathy" DOI Creative Commons
Chang Liu, Jingji Wang, Guoqi Zhu

et al.

Pharmacological Research - Modern Chinese Medicine, Journal Year: 2025, Volume and Issue: unknown, P. 100589 - 100589

Published: Feb. 1, 2025

Language: Английский

Citations

0