Highlights in Science Engineering and Technology,
Journal Year:
2023,
Volume and Issue:
74, P. 749 - 755
Published: Dec. 29, 2023
As
an
essential
trace
element,
zinc
is
required
by
the
human
body,
and
it
associated
with
various
physiological
activities.
It
can
impact
body
development,
brain
function,
bone
growth,
reproductive
health
immune
function.
Zinc
deficiency
cause
many
diseases,
whereas
excess
lead
to
cytotoxicity
as
well.
Thus,
in
significant
sustain
homeostasis.
transporter
protein
(ZnT)
reported
take
responsibility
for
transport
from
cytoplasm
extracellular
or
organelle.
includes
nine
family
members,
they
are
widely
localized
diverse
tissues.
Furthermore,
some
ZnTs
function
not
only
but
also
modulating
Besides,
shown
be
involved
occurrence
development
of
several
including
transient
neonatal
(TNZD),
Parkinson’s
disease
(PD)
others.
This
paper
will
review
molecular
characteristics
their
recent
research
progress
on
which
may
offer
new
insight
into
treatment.
Advanced NanoBiomed Research,
Journal Year:
2023,
Volume and Issue:
3(12)
Published: Nov. 27, 2023
Nonspecific
immunotherapies
often
induce
general
immune
activation
or
suppression.
Conversely,
antigen‐specific
immunotherapy,
which
refers
to
dampening
augmenting
adaptive
immunity
against
a
disease‐specific
antigen,
increases
T‐cell
target
specificity
pathological
tissues,
thereby
reducing
side
effects
on
the
rest
of
system.
Advances
in
engineering
strategies
for
nanomaterials
have
enabled
feasible
modulation
their
physicochemical
features
incorporate
antigens
and
inherently
interact
with
innate
cells,
remarkably
amplifies
orchestration
responses
cancer
autoimmune
diseases.
From
this
contemporary
perspective,
basic
principles
immunotherapy
are
briefly
introduced
we
elucidate
how
latest
nanoengineering
paradigms
regulate
functions
heterogeneous
subsets
such
as
antigen‐presenting
B
regulatory
cytotoxic
T
promoting
treat
diseases
cancer.
An
outlook
prospects
remaining
challenges
been
discussed
for,
translating
scientific
discoveries
powerful
into
medical
advances
thus
offering
new
treatment
modalities
patients
unmet
needs.
Highlights in Science Engineering and Technology,
Journal Year:
2023,
Volume and Issue:
74, P. 749 - 755
Published: Dec. 29, 2023
As
an
essential
trace
element,
zinc
is
required
by
the
human
body,
and
it
associated
with
various
physiological
activities.
It
can
impact
body
development,
brain
function,
bone
growth,
reproductive
health
immune
function.
Zinc
deficiency
cause
many
diseases,
whereas
excess
lead
to
cytotoxicity
as
well.
Thus,
in
significant
sustain
homeostasis.
transporter
protein
(ZnT)
reported
take
responsibility
for
transport
from
cytoplasm
extracellular
or
organelle.
includes
nine
family
members,
they
are
widely
localized
diverse
tissues.
Furthermore,
some
ZnTs
function
not
only
but
also
modulating
Besides,
shown
be
involved
occurrence
development
of
several
including
transient
neonatal
(TNZD),
Parkinson’s
disease
(PD)
others.
This
paper
will
review
molecular
characteristics
their
recent
research
progress
on
which
may
offer
new
insight
into
treatment.