Climate Change and Reproductive Biocomplexity in Fishes: Innovative Management Approaches towards Sustainability of Fisheries and Aquaculture

Water, Journal Year: 2023, Volume and Issue: 15(4), P. 725 - 725

Published: Feb. 12, 2023

The ongoing rapid climate change, combined with the disturbance of fish breeding grounds, may impact reproduction by endangering successful and survival, thus affect viable sustainability in aquaculture systems as well sea. In this study we focus on biocomplexity response to change. Further, propose adaptive strategies, including technological advancements, using a noninvasive non-lethal approach, outline an assisted nutrigenomics approach mitigating reproductive risks posed This was done effort monitor ensure that, livelihood, it provide useful source nutrition for our society.

Language: Английский

---

Heat induces multiomic and phenotypic stress propagation in zebrafish embryos

PNAS Nexus, Journal Year: 2023, Volume and Issue: 2(5)

Published: May 1, 2023

Heat alters biology from molecular to ecological levels, but may also have unknown indirect effects. This includes the concept that animals exposed abiotic stress can induce in naive receivers. Here, we provide a comprehensive picture of signatures this process, by integrating multiomic and phenotypic data. In individual zebrafish embryos, repeated heat peaks elicited both response burst accelerated growth followed slowdown concert with reduced responses novel stimuli. Metabolomes media treated vs. untreated embryos revealed candidate metabolites including sulfur-containing compounds lipids. These transcriptomic changes receivers related immune response, extracellular signaling, glycosaminoglycan/keratan sulfate, lipid metabolism. Consequently, non-heat-exposed (exposed only) experienced catch-up swimming performance. The combination development most, mediated apelin signaling. Our results prove heat-induced propagation toward receivers, inducing phenotypes comparable those resulting direct exposure, utilizing distinct pathways. Group-exposing nonlaboratory line, independently confirm glycosaminoglycan biosynthesis-related gene chs1 mucus glycoprotein prg4a, functionally connected metabolite classes sugars phosphocholine, are differentially expressed hints at production Schreckstoff-like cues leading further within groups, which animal welfare implications for aquatic populations changing climate.

Language: Английский

---

Exploring Thermal Sensitivities and Adaptations of Oxidative Phosphorylation Pathways

Metabolites, Journal Year: 2022, Volume and Issue: 12(4), P. 360 - 360

Published: April 17, 2022

Temperature shifts are a major challenge to animals; they drive adaptations in organisms and species, affect all physiological functions ectothermic organisms. Understanding the origin mechanisms of these is critical for determining whether will be able survive when faced with global climate change. Mitochondrial oxidative phosphorylation thought an important metabolic player this regard, since capacity mitochondria produce energy greatly varies according temperature. However, organism survival fitness depend not only on how much produced, but, more precisely, affected which step process dictates thermal sensitivity. These questions need addressed from new perspective involving complex view mitochondrial its related pathways. In review, we examine effect temperature commonly measured pathways, but mainly focus potential impact lesser-studied pathways steps, including electron-transferring flavoprotein pathway, glycerophosphate dehydrogenase, dihydroorotate choline proline sulfide:quinone oxidoreductase. Our objective reveal avenues research that can address complexity better portray limitations aerobic metabolism.

Language: Английский

---

Genetics of Physiological Variation Within and Between Larval Wild-Type AB and Backcrossed NHGRI-1 Zebrafish (Danio rerio)

Fishes, Journal Year: 2025, Volume and Issue: 10(2), P. 59 - 59

Published: Jan. 31, 2025

Changes in the environment promote variations fish physiological responses. Genetic variation also plays a role variation. To explore of genetics variation, we assessed cardiac function (heart rate, stroke volume, and output), oxygen consumption, yolk conversion efficiency, cost development embryonic larval AB wild-type NHGRI-1 zebrafish (low heterozygosity line backcrossed from wild-type) exposed to different temperature regimes. Fish were fertilization 7 days post-fertilization (dpf) control conditions (28 °C, 21% O2) or low (23 O2), high (33 moderate hypoxia 13% severe 10% O2). We hypothesized that (1) variables will respond similarly both lines (2) data variability be lower than zebrafish. Cardiac decreased at Oxygen consumption was increased by higher fish. Yolk efficiency Cost mainly hypoxia-treated Supporting our hypothesis contributes showed significantly coefficients 84% endpoints. conclude there is strong genetic component fishes are useful models for reducing ‘noise’ backgrounds research fish, which may aid interpretation experimental results facilitate reproducibility.

Language: Английский

---

Brain monoamine changes modulate the corticotropin-releasing hormone receptor 1-mediated behavioural response to acute thermal stress in zebrafish larvae

Molecular and Cellular Endocrinology, Journal Year: 2025, Volume and Issue: unknown, P. 112494 - 112494

Published: Feb. 1, 2025

While central monoamines play a role in regulating stress-related locomotory activity, the modulation of by corticosteroid stress axis shaping acute behavioural responses are unclear. We investigated whether corticotropin-releasing hormone receptor 1 (Crhr1) behavioral response involves monoamine regulation subjecting Crhr1 knockout (crhr1-/-) zebrafish (Danio rerio) to an thermal stressor (TS: + 5 °C above ambient for 60 min). The TS-induced cortisol and hyper activity WT larvae was abolished fish lacking Crhr1. However, both genotypes induced heat shock protein TS. crhr1-/- showed region-specific difference distribution serotonin (5-HT)- tyrosine hydroxylase-positive cells brain. This corresponded with increases whole-body transcript abundance dopamine beta-hydroxylase, tryptophan hydroxylase 2, solute carrier family 6-member 4a. Cotreatment either epinephrine or 5-HT, but not cortisol, able rescue TS-mediated hypo thigmotaxis seen larvae. Together, these results indicate that is essential only mediating hyperactivity also maintaining basal anxiogenic during stress. latter depends on

Language: Английский

---

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

Since stress can be transmitted to congeners via social metabolites, it is paramount understand how the context of abiotic influences aquatic organisms' responses global changes. Here, we integrated transcriptomic and phenotypic zebrafish embryos a UV damage/repair assay following scenarios heat stress, its their combination. Heat preceding exposure had hormetic effect through cellular response DNA repair, rescuing and/or protecting from damage. However, experiencing within negated this molecular lowered larval fitness. We discuss basis interindividual chemical transmission animal groups as another layer complexity environmental stressors.

Language: Английский

---

Behavioural Stress Propagation in Benthic Invertebrates Caused by Acute pH Drop-Induced Metabolites

Frontiers in Marine Science, Journal Year: 2021, Volume and Issue: 8

Published: Nov. 30, 2021

Studies on pH stress in marine animals typically focus direct or species-specific aspects. We here test the hypothesis that a drop to = 7.6 indirectly affects intra- and interspecific interactions of benthic invertebrates by means chemical communication. recorded fitness-relevant behaviours small hermit crabs Diogenes pugilator , green shore Carcinus maenas harbour ragworms Hediste diversicolor response short-term drop, putative metabolites released conspecifics gilt-head sea bream Sparus aurata during 30 min acute drop. Not only did itself impair time find food cue burrowing ragworms, but similar effects were observed under exposure drop-induced metabolites. Stress from S. not its regular control metabolites, also induced avoidance responses all recipient species. Here, we confirm abrupt an abiotic stressor, has capacity trigger release which induce behavioural conspecific heterospecific individuals, can be interpreted as cost. Our findings propagated through communication warrant further research effect size impairments caused characterise their nature.

Language: Английский

---

Differential reproductive plasticity under thermal variability in a freshwater fish ( Danio rerio )

Proceedings of the Royal Society B Biological Sciences, Journal Year: 2022, Volume and Issue: 289(1982)

Published: Sept. 7, 2022

Human-driven increases in global mean temperatures are associated with concomitant thermal variability. Yet, few studies have explored the impacts of variability on fitness-related traits, limiting our ability to predict how organisms will respond dynamic changes. Among myriad organismal responses variability, one most proximate fitness—and, thus, a population's persist—is reproduction. Here, we examine model freshwater fish ( Danio rerio ) responds diel fluctuations that span species's viable developmental range temperatures. We specifically investigate reproductive performance metrics including spawning success, fecundity, egg provisioning and sperm concentration. Notably, apply treatments during two ontogenetic timepoints disentangle relative effects plasticity reversible acclimation. found evidence direct, negative later stages metrics. also complex interactive early late-life exposure beneficial acclimation success modification relationship between fecundity provisioning. Our findings illuminate plastic life-history modifications may undergo as their environments become increasingly variable.

Language: Английский

---

Comparative transcriptome analysis of heat-induced domesticated zebrafish during gonadal differentiation

BMC Genomic Data, Journal Year: 2022, Volume and Issue: 23(1)

Published: May 31, 2022

Abstract Background The influence of environmental factors, especially temperature, on sex ratio is great significance to elucidate the mechanism determination. However, molecular mechanisms by which temperature affects determination remains unclear, although a few candidate genes have been found play role in process. In this study, we conducted transcriptome analysis effects induced high zebrafish during gonad differentiation period. Results Totals 1171, 1022 and 2921 differentially expressed (DEGs) between normal were identified at 35, 45 60 days post-fertilization (dpf) respectively, revealing that heat shock proteins (HSPs) DNA methyltransferases (DNMTs) involved heat-exposed reversal. Gene Ontology (GO) terms Kyoto Encyclopedia Genes Genomes (KEGG) pathway enriched individuals after treatment included Fanconi anemia (FA) pathway, cell cycle, oocyte meiosis homologous recombination. Conclusions Our study provides results comparative analyses reveals heat-induced masculinization strongly related expression HSPs DNMTs FA differentiation.

Language: Английский

---

Consequences of directly- and indirectly-experienced heat stress in a mutagenic environment

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Oct. 5, 2023

Abstract Climate change increases the frequency and duration of heat events. Negative effects stress may be exacerbated through action social metabolites between aquatic animals. Whilst early life stages are vulnerable to stress-induced damage, they deploy cellular mechanisms protect cells against mutagens such as ultraviolet rays (UV). Little is known about fate fish embryos which have experienced in a mutagenic environment. The present study exposed zebrafish one three history treatments consisting direct (TS+UV), context via (SM+UV), their combination TS+SM+UV before UVB/UVA damage/repair assay. We measured phenotypic transcriptomic responses these treatments, estimated mutational damage DNA mutation frequencies RNA integrity values. Compared UV-treated controls (C+UV), preceding UV assay altered keratin cell structuring-related pathways, associated with longer over-developed pericardia displaying behavioural hypoactivity. Relative C+UV, exposure had hormetic effect by stimulating response facilitating repair, rescued from subsequent improved apparent fitness. However, combined overwhelmed assay, annihilated effect, introduced mutations, lowered generated laboratory, findings provide an important baseline for understanding consequences natural environments, where occurs within context. Highlights Heat shock response, antioxidants, repair. protected and/or reducing single nucleotide variants observed RNA, lowering malformations, accelerating development. Heat-stressed released that initiated keratin, immune, structuring receivers, turn increasing body sizes but without UV-induced malformations. UV, fitness-relevant performance. during embryogenesis led differential outcomes showing nonlinear relationship intensity. Summary statement Sublethal protects environment, this protective lost when additionally each other chemical cues. Graphical abstract

Language: Английский

---