Food deprivation is associated with telomere elongation during hibernation in a primate DOI
Marina B. Blanco, Dana L. Smith, Lydia K. Greene

et al.

Biology Letters, Journal Year: 2025, Volume and Issue: 21(2)

Published: Feb. 1, 2025

Telomeres, the protective ends of chromosomes, progressively shorten due to incomplete mitotic replication and oxidative stress. In some organisms, transient telomere elongation may occur, for example, when individuals have an energy surplus counter stress-induced life events or elongating telomeres is a last chance increase fitness. Mammalian hibernators are good models test dynamics, as they cycle between prolonged bouts metabolic depression (torpor) punctuated by short surges euthermia (arousals). We studied captive fat-tailed dwarf lemurs ( Cheirogaleus medius ), strepsirrhine primate hibernators, that were food-deprived n = 8) fed daily 7) during hibernation (4.5 months). compared lengths, assayed via qPCR from oral swabs, at five strategic time points span full year. Food-deprived subjects underwent multi-day torpor/arousal cycles, lost considerable body mass elongated but shortened them upon emergence. contrast, food-provisioned ate daily, more slowly, shallower shorter torpor experienced little change in lengths same periods. Our results highlight complex relationship balance expression. Further investigation warranted elucidate regulation mechanisms these hibernators.

Language: Английский

EDITORIAL: Thermoregulatory and metabolic adaptations in a changing world DOI
Julia Nowack, Katie E. Marshall, Jérémy Terrien

et al.

Journal of Thermal Biology, Journal Year: 2025, Volume and Issue: unknown, P. 104062 - 104062

Published: Jan. 1, 2025

Language: Английский

Citations

0
Food deprivation is associated with telomere elongation during hibernation in a primate DOI
Marina B. Blanco, Dana L. Smith, Lydia K. Greene

et al.

Biology Letters, Journal Year: 2025, Volume and Issue: 21(2)

Published: Feb. 1, 2025

Telomeres, the protective ends of chromosomes, progressively shorten due to incomplete mitotic replication and oxidative stress. In some organisms, transient telomere elongation may occur, for example, when individuals have an energy surplus counter stress-induced life events or elongating telomeres is a last chance increase fitness. Mammalian hibernators are good models test dynamics, as they cycle between prolonged bouts metabolic depression (torpor) punctuated by short surges euthermia (arousals). We studied captive fat-tailed dwarf lemurs ( Cheirogaleus medius ), strepsirrhine primate hibernators, that were food-deprived n = 8) fed daily 7) during hibernation (4.5 months). compared lengths, assayed via qPCR from oral swabs, at five strategic time points span full year. Food-deprived subjects underwent multi-day torpor/arousal cycles, lost considerable body mass elongated but shortened them upon emergence. contrast, food-provisioned ate daily, more slowly, shallower shorter torpor experienced little change in lengths same periods. Our results highlight complex relationship balance expression. Further investigation warranted elucidate regulation mechanisms these hibernators.

Language: Английский

Citations

0