Ultrafast Synthesis of Hard Carbon Anodes for Sodium‐ion Batteries: An Intense‐Pulsed‐Light‐Assisted Approach to Photothermal Carbonization of Polymer/Carbon Nanotube Composite Films

Small Methods, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 15, 2025

The conventional carbonization process for synthesizing hard carbons (HCs) requires high-temperature furnace operations exceeding 1000 °C, leading to excessive energy consumption and lengthy processing times, which necessitates the exploration of more efficient synthesis methods. This study demonstrates rapid preparation HC anodes using intense pulsed light (IPL)-assisted photothermal without prolonged complex typical traditional A composite film microcrystalline cellulose (MCC) single-walled carbon nanotubes (SWCNTs) is carbonized at high temperatures in less than 1 min. SWCNTs efficiently absorbed energy, enabling ultrafast heating eliminating need prolonged, high-energy furnace-based processes. IPL-assisted exhibited excellent electrochemical performance, with an initial desodiation capacity 260.4 mAh g⁻¹anode 97.5% retention after 200 cycles. These results are comparable those achieved processes, such as carbonizing 1200 validating effectiveness Additionally, surface structural analyses revealed development pseudo-graphitic domains, crucial enhanced sodium-ion storage. research highlights a viable, time-efficient, energy-saving alternative methods, offering sustainable pathway large-scale production future battery technologies.

Language: Английский

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Changes in the distribution of the tear film lipid layer after intensive pulsed light combined with meibomian gland expression in patients with meibomian gland dysfunction

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(2), P. e0316935 - e0316935

Published: Feb. 28, 2025

Purpose This study aimed to investigate changes in dry eye disease (DED) parameters and tear film lipid layer distribution after intensive pulse light (IPL) combined with meibomian gland expression (MGX) patients dysfunction (MGD). Methods retrospective included 218 diagnosed MGD who underwent IPL MGX. Various DED parameters, including thickness (LLT), were measured using a Placido disc analyzer slit lamp. Inferior corneal images quantified divided into upper, lower, nasal, temporal quadrants, further subdivision six parts from top bottom Python. Results The ocular surface index, expressibility, quality scores significantly improved three treatment sessions. Slit-lamp-measured also improved, excluding the fluorescein-stained meniscus height. Redness nasal limbal bulbar conjunctivae decreased. mean LLT tended increase treatment. upper half of images, but not lower half, increased significantly, difference between two halves decreasing 34.46 ± 15.73 30.27 14.63 nm (p = 0.031). When vertical was analyzed by equal bottom, average decreased uppermost segment Conclusion MGX reduced lipids reducing stasis. Thus, is useful tool for analyzing MGD.

Language: Английский

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A Comparative Study of Intense Pulsed Light with Two Different Filters in Meibomian Gland Dysfunction: A Prospective Randomized Study

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(1), P. 199 - 199

Published: Jan. 1, 2025

Objectives: To compare the long-term efficacy and safety of intense pulsed light (IPL) treatments using a 590-nm an acne filter. Methods: In this prospective, randomized, paired-eye trial study, 30 patients with moderate severe meibomian gland dysfunction (MGD) were followed up for at least one month after their last treatment. Group A received IPL treatment filter, type notch filter that blocks wavelengths between 600 800 nm, allowing to emit 400–600 nm 800–1200 nm. B 590 cut-off below Clinical parameters, including tear osmolarity, matrix metalloproteinase (MMP)-9 expression, break-up time, ocular surface staining scores, Schirmer’s test I, lid margin telangiectasia MG expressibility/secretion Ocular Surface Disease Index measured baseline, 1, 6, 12 months Results: linear mixed model, significant time effects on all clinical except MMP-9 grades I results, observed within each group. However, interactions points (baseline, 6 months, months) groups (Group A, B) not significant. The generalized estimating equation model showed no interaction positivity; however, effect positivity was in decrease when compared baseline months. Conclusions: modality MGD demonstrated therapeutic year under strictly controlled self-administration other treatments. is promising option reducing patients.

Language: Английский

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Intense Pulsed Light in the Treatment of Dry Eye and Meibomian Gland Dysfunction in Patients With Chronic Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis

Cornea, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 14, 2025

Purpose: To evaluate the efficacy and safety of intense pulsed light (IPL) combined with meibomian gland expression (MGX) for treatment dry eye disease dysfunction associated chronic Stevens–Johnson syndrome toxic epidermal necrolysis. Methods: This prospective noncomparative interventional study included 29 patients (58 eyes) who underwent 3 sessions IPL MGX at 2-week intervals. Subjective symptoms (ocular surface index score) objective tests: matrix metalloproteinase 9, tear meniscus height, bulbar redness score, film lipid layer thickness (LLT), Schirmer I test, conjunctival corneal staining, loss, score [meibomian (MGS)], break-up time were assessed baseline after 4, 8, 12 weeks. Results: Twenty-nine individuals (57 in this analysis. The ocular decreased significantly from 60.07 ± 23.34 (baseline) to 38.36 22.39 (after 90 days) ( P < 0.01). fluorescein lissamine green staining scores, MGS, LLT improved In contrast, there no significant changes height values, 9 positivity, meibography superior inferior eyelids, time. Ocular or skin complications not observed. Conclusions: Three therapy followed by seemed be safe effective treating dysfunction, improving vision-related quality life, symptoms, signs, such as days

Language: Английский

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Clinical Factors Predicting Favorable Response to Intense Pulsed Light Therapy for Refractory Meibomian Gland Dysfunction: A 6-Month Cohort Study

Cornea, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 18, 2025

Purpose: Meibomian gland dysfunction (MGD) is a global health disorder, which can have deleterious effect on visual function and quality of life. Intense pulsed light (IPL) therapy has been shown to ameliorate MGD. However, the optimal candidates who would benefit most from IPL remain undetermined. Therefore, we aimed in this study identify clinical factors associated with favorable outcomes patients MGD after therapy. Methods: This single-center retrospective included refractory treated course combined meibomian expression, follow-up period 6 months. The outcome measures were standardized patient evaluation eye dryness (SPEED) score, tear breakup time, lid telangiectasia, meibum quality, expressibility. Good responders defined as those at least 1-point reduction SPEED score 1-grade decrease Data analyzed using t test, chi-square binary logistic regression analysis. Results: A total 90 eyes (good responders: 48 eyes, nonresponders: 42 eyes) included. Univariate analysis revealed that good had higher baseline than nonresponders. Multivariate showed more severe symptoms, inspissated meibum, better expressibility, milder degree telangiectasia independently response. Conclusions: Our findings suggest worse poorer or less obstruction are likely response

Language: Английский

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Clinical ocular surface characteristics and expression of MUC5AC in diabetics: a population-based study

Eye, Journal Year: 2024, Volume and Issue: 38(16), P. 3145 - 3152

Published: July 28, 2024

Language: Английский

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Response of tear cytokines following intense pulsed light combined with meibomian gland expression for treating meibomian gland dysfunction-related dry eye

Frontiers in Endocrinology, Journal Year: 2022, Volume and Issue: 13

Published: Sept. 15, 2022

Purpose This study compared the changes in tear inflammatory cytokine levels after intense pulsed light (IPL) combined with meibomian gland expression (MGX) (IPL group) and instant warm compresses MGX (physiotherapy as treatments for dysfunction (MGD)-related dry eye disease (DED) to explore their similarities differences therapeutic mechanisms. Methods was a post-hoc analysis of randomized controlled trial. Thirteen patients MGD-related DED were enrolled each group received three correspondingly 3-week intervals. The 20 cytokines, namely, TNF-α, IL-6, MMP-9, CXCL8/IL-8, CXCL10/IP-10, IL-10, EGF, IL-6R, IL-1β, IFN-γ, lactoferrin, Fas ligand, IL-17A, LT-α, S100A9, LCN2/NGAL, IL-13, IL-12/IL-23p40, Fas, CCL11/Eotaxin, measured at baseline, before second third treatments, 3 weeks treatment. primary outcome difference between baseline last measurement, trends analyzed measurement point. Results At significant decrease observed all cytokines both IPL physiotherapy groups baseline. showed greater reductions CCL11/Eotaxin than group. Lipocalin-2/NGAL continued treatment time. Important interactions found IL-6 IL-13 levels, where first decreased then slightly increased treatment, while they Conclusions mechanisms treating associated reducing inflammation, superiority could be attributed its better inhibitory effect on like IL-6. In addition, several downward trend during suggesting that vicious cycle suppressed.

Language: Английский

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Intense Pulsed Plus Low-Level Light Therapy in Meibomian Gland Dysfunction

Clinical ophthalmology, Journal Year: 2021, Volume and Issue: Volume 15, P. 2803 - 2811

Published: June 1, 2021

To analyse the clinical outcome in patients with meibomian gland dysfunction (MGD) who underwent intense pulsed light (IPL) plus low-level therapy (LLL).The prospective non-comparative study included identified by MGD altered interferometry and lower loss area of glands (LAMG), IPL LLL, between July 2020 August 2020. A multimodal assessment was performed before, 2-3 weeks, 6 months after treatment. The main lipid layer thickness (LLT) secondary outcomes were ocular surface disease index (OSDI) score, presence corneal fluorescein staining (CFS), blink rate (BR), Schirmer test (ST), tear meniscus height (TMH), osmolarity (OSM), non-invasive break-up time (NIBUT) LAMG.This 62 eyes 31 patients, 61.3% female, a mean age 66.94±9.08 years at LLL LLT (<0.001) grades improved OSDI score (p<0.001) from 45.02±21.17 (severe symptoms) to 22.35±17.68 (moderate weeks 8.24±17.9.91 (normal) CFS 51.6% (32/62) before 45.2% (28/62) (p=0.293) ST (p=0.014) improved; OSM mild worsened (p<0.001); TMH, NIBUT LAMG did not modify No patient suffered any adverse effects.IPL combined effective safe, improving decreasing level symptoms.

Language: Английский

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Pulsed Light Therapy in the Management of Dry Eye Disease: Current Perspectives

Clinical ophthalmology, Journal Year: 2022, Volume and Issue: Volume 16, P. 3883 - 3893

Published: Nov. 1, 2022

Purpose: To review the indications and efficacy of Intense Pulsed Light (IPL) application in treatment Meibomian Gland Dysfunction (MGD). Its main purpose is to describe its physiology, efficacy, indications, adverse effects. Patients Methods: A two database (PubMed, EMBASE) search was performed from July 2017 2022 using MeSH terms ("Intense Light" AND ("Meibomian Dysfunction" OR "Dry Eye"). We included randomized studies systematic reviews with meta-analysis. Exclusion criteria were non-randomized trials, enrolling non-MGD dry eye disease, other works older than 5 years. Results: Current literature shows that IPL an effective safe modality for severe eye. Available evidence improvement symptoms objective indicators, such as noninvasive breakup time, thickness lipid layer, Schirmer test. However, our concluded beneficial effects may lose some at 6-months after initial session, subsequent sessions be required. Thus, should not considered first-line therapy MGD but instead adjuvant option standard care. The optimal remains unknown tailored according each patient's phenotype, clinician's experience, available technology. There down-regulate pro-inflammatory markers (such interleukin (IL) 6, IL17a, IL-1) Prostaglandin E2 (PGE2). Conclusion: a multifactorial disease seems promising modality. Despite this, more needed study benefits – since this emerging technology, it expected increase comparative following years, longer follow-up periods, which enable precise conclusions about Keywords: meibomian gland dysfunction, intense pulsed light, low-level light therapy, near-infrared ocular surface index

Language: Английский

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Eyelid Exfoliation Treatment Efficacy and Safety in Dry Eye Disease, Blepharitis, and Contact Lens Discomfort Patients: A Systematic Review

Asia-Pacific Journal of Ophthalmology, Journal Year: 2023, Volume and Issue: 12(3), P. 315 - 325

Published: April 12, 2023

To determine the efficacy and safety of eyelid exfoliation treatment in dry eye disease (DED), blepharitis, contact lens (CL) discomfort patients.A systematic review that included only full-length randomized controlled studies, reporting effects 2 databases, PubMed Web Science, was performed according to Preferred Reporting Items for Systematic Reviews Meta-analyses statement. The search period between October 29, 2022 December 6, 2022. Cochrane risk bias tool used analyze quality studies selected.A total 7 were this review. Eyelid influence on DED, CL analyzed 4, respectively. achieved a better improvement than control group interventions all reported variables. mean differences both groups as follows: Ocular Surface Disease Index score -5.0 ± 0.9 points, tear breakup time 0.43 0.2 seconds, ocular surface staining -1.4 1.5 meibomian glands secretions 1.2 1.1 yielding liquid secretion 0.6 0.3 microorganism load -3.2 4.7 Contact Lens Dry Eye Questionnaire-8 -2.15 0.1 points. Minimal (n = 13) irritation 2) main complications after an treatment.Eyelid is safe effective should be indicated discomfort.

Language: Английский

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