Research Square (Research Square),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Dec. 6, 2023
Abstract
Purpose
:
Environmental
exposure
to
hazardous
chemicals
have
been
linked
many
detrimental
health
effects.
It
is
critical
effective
biomonitoring
methods
monitor
the
levels
of
these
in
humans
better
evaluate
key
environmental
exposures
that
increase
risk
chronic
disease
and
death.
Traditional
utilizing
blood
urine
limited
due
specialized
skills
invasiveness
collecting
fluid
samples.
The
systematic
review
focuses
on
tear
fluid,
which
largely
under-researched,
as
promising
alternative
traditional
fluids.
objective
practicability
using
human
for
exposures,
highlighting
potential
pitfalls
opportunities.
Recent
finding
Tear
represents
a
method
assessing
participants
can
conveniently
collect
samples
from
comfort
their
home.
uniquely
interfaces
with
external
environment
at
air-tear
interface,
providing
surface
airborne
diffuse
into
ocular
interact
biomolecules.
also
contains
molecules
internal
travelled
tears
by
crossing
blood-tear
barrier.
Our
shows
be
used
identify
environments
differentiate
between
different
groups.
Summary
provides
analysis
current
state
knowledge
tear-based
draws
attention
promise
noninvasively
increasing
access
assessment.
will
become
acceptable
routine
use
more
individual
inter
lab
studies
focus
broadly
identifying
quantify
markers
tears,
understanding
factors
influence
reliability
standardizing
method.
Oftalmología clínica y experimental.,
Journal Year:
2024,
Volume and Issue:
17(S1Eng)
Published: Dec. 10, 2024
The
tear
film
has
a
complex
composition
allowing
it
fulfill
multiple
functions,
such
as
optical,
lubrication,
immunological,
endocrine,
and
neurotrophic,
which
are
relevant
for
visual
health.
Alterations
in
its
components,
both
quality
quantity,
will
affect
homeostasis,
also
impacting
the
ocular
surface,
leading
to
condition
known
“dry
eye”.
Dry
eye
high
global
prevalence,
is
further
increasing
due
environmental
factors
(mainly
screen
mainly)
overall
rise
life
expectancy.
Several
products
available
treatment,
but
lubricants,
generally
referred
“artificial
tears”,
continue
be
crucial.
There
wide
variety
of
lubricant
formulations
with
different
indications,
which,
when
used
appropriately
according
type
severity
dry
eye,
allow
effective
customized
treatment.
Considering
complexity
relevance
this
issue,
Latin
American
Study
Group
on
Lubricants
Eye
(LUBOS)
was
formed.
This
work
represents
consensus
aim
creating
diagnostic
therapeutic
algorithm
focused
proper
use
providing
practical
guidance
general
ophthalmologists.
Clinical ophthalmology,
Journal Year:
2024,
Volume and Issue:
Volume 18, P. 3925 - 3934
Published: Dec. 1, 2024
Anorexia
nervosa
(AN)
is
a
psychiatric
eating
disorder
characterized
by
body
mass
index
(BMI)
≤
18.5,
fear
of
gaining
weight,
and
distorted
perception
weight.
With
increasing
rates
myopia,
there
population
patients
who
concurrently
develop
AN
may
seek
corneal
refractive
surgery.
This
study
reviews
the
ophthalmic
manifestations
provides
preliminary
guidelines
for
with
undergoing
The
literature
search
was
conducted
through
PubMed,
Scopus,
Ovid
databases
June
2,
2024,
publications
detailing
ocular
AN.
These
findings
were
then
considered
in
context
potential
complications
after
surgery,
preoperative
formulated.
Twelve
articles
described
total
114
(227
eyes)
manifestations.
Among
studied
eyes,
14%
had
surface
abnormalities,
5%
cataracts/visual
disturbances,
64%
posterior
segment
20%
orbital/neurological
abnormalities.
Various
increase
risk
delayed
wound
healing,
dryness,
perioperative
bleeding,
flap-related
complications,
poor
visual
outcomes
BMI
suspected
must
be
assessed,
should
screened
diagnosis
If
mildly
moderately
underweight
have
normal
medical
workups,
they
proceed
typical
workup
Ultimately,
decision
to
recommend
elective
surgery
these
rests
surgeon.
foundation
future
research,
encouraging
collaboration
across
disciplines
more
comprehensive
managing
this
patient
population.
Current Opinion in Allergy and Clinical Immunology,
Journal Year:
2024,
Volume and Issue:
24(5), P. 397 - 403
Published: Aug. 13, 2024
Integrative
medicine
techniques
are
increasingly
accepted
into
the
treatment
paradigm
for
many
chronic
disorders
including
eye
disease.
Over
71%
of
patients,
67%
those
with
disorders,
use
some
form
therapy.
Physicians
should
be
well
versed
in
evidence-based
therapies
to
know
how
refer
patients
best
complimentary
care.
We
highlight
most
effective
integrative
therapeutics
from
different
complementary
paradigms
offer
a
framework
approaching
therapy
ocular
surface
(OSDs).
Research Square (Research Square),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Dec. 6, 2023
Abstract
Purpose
:
Exposures
to
hazardous
chemicals
have
been
linked
many
detrimental
health
effects.
It
is
critical
effective
biomonitoring
methods
measure
the
levels
of
these
in
humans
better
evaluate
key
environmental
exposures
that
increase
risk
chronic
disease
and
death.
Traditional
utilizing
blood
urine
limited
due
specialized
skills
invasiveness
collecting
fluid
samples.
The
systematic
review
focuses
on
tear
fluid,
which
largely
under-researched,
as
promising
alternative
traditional
fluids.
objective
practicability
using
human
for
exposures,
highlighting
potential
pitfalls
opportunities.
Recent
finding
Tear
represents
a
method
assessing
exposures.
uniquely
interfaces
with
external
environment
at
air-tear
interface,
providing
surface
airborne
diffuse
into
ocular
interact
biomolecules.
also
contains
molecules
from
internal
travelled
tears
by
crossing
blood-tear
barrier.
Our
shows
can
be
used
identify
environments
differentiate
between
different
exposure
groups.
Summary
provides
analysis
current
state
knowledge
tear-based
draws
attention
promise
noninvasively
increasing
access
assessment.
will
become
acceptable
routine
use
more
individual
inter
lab
studies
focus
broadly
identifying
quantify
markers
tears,
understanding
factors
influence
reliability
standardizing
method.
Research Square (Research Square),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Dec. 6, 2023
Abstract
Purpose
:
Environmental
exposure
to
hazardous
chemicals
have
been
linked
many
detrimental
health
effects.
It
is
critical
effective
biomonitoring
methods
monitor
the
levels
of
these
in
humans
better
evaluate
key
environmental
exposures
that
increase
risk
chronic
disease
and
death.
Traditional
utilizing
blood
urine
limited
due
specialized
skills
invasiveness
collecting
fluid
samples.
The
systematic
review
focuses
on
tear
fluid,
which
largely
under-researched,
as
promising
alternative
traditional
fluids.
objective
practicability
using
human
for
exposures,
highlighting
potential
pitfalls
opportunities.
Recent
finding
Tear
represents
a
method
assessing
participants
can
conveniently
collect
samples
from
comfort
their
home.
uniquely
interfaces
with
external
environment
at
air-tear
interface,
providing
surface
airborne
diffuse
into
ocular
interact
biomolecules.
also
contains
molecules
internal
travelled
tears
by
crossing
blood-tear
barrier.
Our
shows
be
used
identify
environments
differentiate
between
different
groups.
Summary
provides
analysis
current
state
knowledge
tear-based
draws
attention
promise
noninvasively
increasing
access
assessment.
will
become
acceptable
routine
use
more
individual
inter
lab
studies
focus
broadly
identifying
quantify
markers
tears,
understanding
factors
influence
reliability
standardizing
method.
