Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: unknown, P. 110400 - 110400
Published: Sept. 1, 2024
Language: Английский
Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: unknown, P. 110400 - 110400
Published: Sept. 1, 2024
Language: Английский
Journal of Water Process Engineering, Journal Year: 2023, Volume and Issue: 57, P. 104597 - 104597
Published: Dec. 12, 2023
Language: Английский
Citations
49Materials Chemistry and Physics, Journal Year: 2024, Volume and Issue: 318, P. 129300 - 129300
Published: April 4, 2024
Language: Английский
Citations
23Sensors and Actuators Reports, Journal Year: 2024, Volume and Issue: 7, P. 100195 - 100195
Published: April 24, 2024
Efficient and timely detection of cancer biomarkers is pivotal for enhancing treatment outcomes mitigating patient mortality. This study addresses the pressing need a swift, accurate, non-invasive method to identify antigen 125 (CA125), vital biomarker in ovarian cancer. Leveraging growing prominence nano-biosensors their high selectivity sensitivity, we present development characterization an innovative electrochemical nano-biosensor. The sensor, featuring aptamer strands immobilized on glassy carbon electrode modified with graphitic nitrides, molybdenum disulfide, magnetic nanoparticles (g-C3N4/MoS2/Fe3O4), demonstrates superior sensitivity accuracy CA125 detection. Utilizing methylene blue labeled ferrocyanide label-free detection, our aptasensor achieves low limit (LOD) at 0.202 U.mL−1 0.215 U.mL−1, respectively, broad range from 2 10 U.mL−1. exhibits pronounced affinity CA125, demonstrating enhanced stability compared other biomolecules. Crucially, evaluation both normal serum samples underscores aptasensor's remarkable performance. These findings not only establish robust foundation future research diagnosis but also highlight potential clinical impact nano-biosensor advancing early methodologies.
Language: Английский
Citations
18Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2025, Volume and Issue: 709, P. 136130 - 136130
Published: Jan. 7, 2025
Language: Английский
Citations
4Journal of environmental chemical engineering, Journal Year: 2023, Volume and Issue: 11(5), P. 110477 - 110477
Published: June 30, 2023
Language: Английский
Citations
23Sensing and Bio-Sensing Research, Journal Year: 2024, Volume and Issue: 45, P. 100669 - 100669
Published: June 28, 2024
Detecting ovarian cancer at an early stage is crucial for enhancing patient outcomes, underscoring the demand efficient and non-invasive detection method. Cancer antigen 125 (CA125) a vital biomarker in detection, there pressing to develop quick, sensitive, simple Nanobiosensors are increasingly being used by scientists due their high selectivity sensitivity, allowing swift precise of wide range biomarkers. This study aimed design fabricate electrochemical nanobiosensor that could accurately selectively detect CA125. The employed graphitic carbon nitrides, molybdenum disulfide, polyaniline (g-C3N4/MoS2/PANI) stabilize aptamer strands on modified glassy electrode. aptasensor was perform labeled CA125, utilizing methylene blue label-free ferrocyanide methods. Ferrocyanide limits were determined be 0.196 U.mL−1 blue, with linear 2–10 detection. results showed electrode exhibited towards CA125 superior stability compared other biomolecules. also displayed impressive performance when analyzing serum patients healthy people. These findings hold significant promise future investigation diagnosis. novel may aid management cancer, ultimately leading better outcomes.
Language: Английский
Citations
15TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 180, P. 117964 - 117964
Published: Sept. 7, 2024
Language: Английский
Citations
14RSC Applied Interfaces, Journal Year: 2024, Volume and Issue: 1(3), P. 340 - 429
Published: Jan. 1, 2024
The pharmaceuticals industry has played an important role in developing medicines for improving health and quality of life treating humans animals around the world.
Language: Английский
Citations
12Ceramics International, Journal Year: 2024, Volume and Issue: 50(11), P. 18594 - 18608
Published: Feb. 27, 2024
Language: Английский
Citations
10Journal of Alloys and Compounds, Journal Year: 2024, Volume and Issue: 980, P. 173655 - 173655
Published: Jan. 26, 2024
Language: Английский
Citations
8