Treatment Noncompletion and Shorter Radiation Regimens Among US Patients With Prostate Cancer: A Focus on Asian American and Pacific Islander Patients DOI

Rohit V. Mantena,

Rishabh Bhadouriya,

Urvish Jain

et al.

The Prostate, Journal Year: 2025, Volume and Issue: unknown

Published: March 31, 2025

ABSTRACT Background Higher rates of radiation therapy (RT) noncompletion may be associated with certain demographic groups in patients prostate cancer (PC). We examined disparities and receipt shorter RT regimens among disaggregated Asian American Pacific Islander the US. Methods performed a retrospective cohort analysis all diagnosed localized PC (2004–2017) National Cancer Database who identified as White, East Asian, Southeast Islander, or South were treated definitive RT. The two primary outcomes 1) treatment 2) receiving regimens. Regression models adjusted for relevant sociodemographic clinical factors. Results analytic was comprised 143,379 [White, n = 140,656 (98.10%); 1,150 (0.80%); 925 (0.65%); 195 (0.14%); 453 (0.32%)]. On multivariable analysis, increased rate compared to White (Southeast vs. White; OR: 1.55 [95% CI: 1.29–1.86], p < 0.001). Geographic region facility within United States also significant, from Atlantic (OR: 1.32 1.24–1.41], 0.001), North Central 1.09 1.03–1.17], 0.007), 1.54 1.41–1.68], West 1.14 1.04–1.24], 0.005) regions had higher comparison New England. Distance facility, presence comorbidities, education attainment significantly impacted well. Additionally, our study reports short course substantially SBRT 2.60 1.10–6.16], 0.030) patients, while Hispanic lower 0.48 0.40–0.57], Furthermore, urban 0.68 0.61–0.76], 0.001) metro 0.50 0.39–0.65], facilities reduced access than rural areas. Patients received Middle 3.28 2.91–3.68], 2.72 2.40–3.09], 1.53 1.34–1.75], 3.07 2.61–3.63], 2.35 2.02–2.75], Mountain 2.45 2.01–2.97], Conclusions This found that patients. access–a traditional therapies–were based on race/ethnicity geographical Our findings emphasize heterogeneous differences amongst diverse support need further research inform targeted interventions.

Language: Английский

Treatment Noncompletion and Shorter Radiation Regimens Among US Patients With Prostate Cancer: A Focus on Asian American and Pacific Islander Patients DOI

Rohit V. Mantena,

Rishabh Bhadouriya,

Urvish Jain

et al.

The Prostate, Journal Year: 2025, Volume and Issue: unknown

Published: March 31, 2025

ABSTRACT Background Higher rates of radiation therapy (RT) noncompletion may be associated with certain demographic groups in patients prostate cancer (PC). We examined disparities and receipt shorter RT regimens among disaggregated Asian American Pacific Islander the US. Methods performed a retrospective cohort analysis all diagnosed localized PC (2004–2017) National Cancer Database who identified as White, East Asian, Southeast Islander, or South were treated definitive RT. The two primary outcomes 1) treatment 2) receiving regimens. Regression models adjusted for relevant sociodemographic clinical factors. Results analytic was comprised 143,379 [White, n = 140,656 (98.10%); 1,150 (0.80%); 925 (0.65%); 195 (0.14%); 453 (0.32%)]. On multivariable analysis, increased rate compared to White (Southeast vs. White; OR: 1.55 [95% CI: 1.29–1.86], p < 0.001). Geographic region facility within United States also significant, from Atlantic (OR: 1.32 1.24–1.41], 0.001), North Central 1.09 1.03–1.17], 0.007), 1.54 1.41–1.68], West 1.14 1.04–1.24], 0.005) regions had higher comparison New England. Distance facility, presence comorbidities, education attainment significantly impacted well. Additionally, our study reports short course substantially SBRT 2.60 1.10–6.16], 0.030) patients, while Hispanic lower 0.48 0.40–0.57], Furthermore, urban 0.68 0.61–0.76], 0.001) metro 0.50 0.39–0.65], facilities reduced access than rural areas. Patients received Middle 3.28 2.91–3.68], 2.72 2.40–3.09], 1.53 1.34–1.75], 3.07 2.61–3.63], 2.35 2.02–2.75], Mountain 2.45 2.01–2.97], Conclusions This found that patients. access–a traditional therapies–were based on race/ethnicity geographical Our findings emphasize heterogeneous differences amongst diverse support need further research inform targeted interventions.

Language: Английский

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